Cholesterol biosynthesis - Reaction Information

  get more information at the BRENDA pathway page
Reaction
(R)-mevalonate + CoA + 2 NADP+ = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H+
BRENDA:
BR29297show the reaction diagram, BR50597show the reaction diagram, BS188050show the reaction diagram, BS451044show the reaction diagram
KEGG:
R02082show the reaction diagram
MetaCyc:
1.1.1.34-RXNshow the reaction diagram
SABIO-RK:
2092
Enzymes
show all sequences1.1.1.34 (hydroxymethylglutaryl-CoA reductase (NADPH))
show all sequences1.1.1.88 (hydroxymethylglutaryl-CoA reductase)
show all sequences1.1.1.B38 (hydroxymethylglutaryl-CoA reductase [NAD(P)H])
Other pathways
BRENDA:
mevalonate metabolism
KEGG:
Terpenoid backbone biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites
MetaCyc:
mevalonate pathway IV (archaea),
mevalonate pathway III (Thermoplasma),
mevalonate pathway I (eukaryotes and bacteria),
isoprene biosynthesis II (engineered),
mevalonate pathway II (haloarchaea)
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1.1.1.34, 1.1.1.88, 1.1.1.B38
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