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BRENDA KEGG MetaCyc

glutamate and glutamine metabolism (BRENDA)

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EC Number Recommended Name Reaction BRENDA Pathway Name KEGG Pathway Name MetaCyc Pathway Name Reaction ID BRENDA Reaction ID KEGG Reaction ID MetaCyc Reaction ID SABIO-RK
show all sequences1.4.1.13 glutamate synthase (NADPH) 2 L-glutamate + NADP+ = L-glutamine + 2-oxoglutarate + NADPH + H+ glutamate and glutamine metabolism Alanine, aspartate and glutamate metabolism,
Nitrogen metabolism,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
Biosynthesis of amino acids
L-glutamine degradation II,
L-glutamate biosynthesis I
BR36861 show the reaction diagram R00114 show the reaction diagram GLUTAMATESYN-RXN show the reaction diagram 694
show all sequences4.2.1.34 (S)-2-Methylmalate dehydratase (S)-2-Methylmalate = 2-methylfumarate + H2O glutamate and glutamine metabolism C5-Branched dibasic acid metabolism,
Metabolic pathways
L-glutamate degradation VI (to pyruvate) BR414 show the reaction diagram R03693 show the reaction diagram S-2-METHYLMALATE-DEHYDRATASE-RXN show the reaction diagram  
show all sequences1.4.7.1 glutamate synthase (ferredoxin) 2 L-Glutamate + 2 Oxidized ferredoxin <=> L-Glutamine + 2-Oxoglutarate + 2 Reduced ferredoxin + 2 H+ glutamate and glutamine metabolism Glyoxylate and dicarboxylate metabolism,
Nitrogen metabolism,
Microbial metabolism in diverse environments
ammonia assimilation cycle II,
L-glutamine biosynthesis III,
L-glutamate biosynthesis V
  R00021 show the reaction diagram GLUTAMATE-SYNTHASE-FERREDOXIN-RXN show the reaction diagram  
show all sequences1.4.7.1 glutamate synthase (ferredoxin) 2 L-glutamate + oxidized ferredoxin = L-glutamine + 2-oxoglutarate + reduced ferredoxin + 2 H+ glutamate and glutamine metabolism     BR36886 show the reaction diagram      
show all sequences6.1.1.24 glutamate-tRNAGln ligase ATP + L-Glutamate + tRNA(Gln) <=> AMP + Diphosphate + L-Glutamyl-tRNA(Gln) glutamate and glutamine metabolism Aminoacyl-tRNA biosynthesis,
Metabolic pathways
glutaminyl-tRNAgln biosynthesis via transamidation   R03651 show the reaction diagram RXN-9386 show the reaction diagram  
show all sequences6.1.1.17 glutamate-tRNA ligase tRNA(Glu) + L-Glutamate + ATP <=> L-Glutamyl-tRNA(Glu) + Diphosphate + AMP glutamate and glutamine metabolism Porphyrin and chlorophyll metabolism,
Aminoacyl-tRNA biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments
    R05578 show the reaction diagram    
show all sequences6.1.1.24 glutamate-tRNAGln ligase tRNA(Glu) + L-Glutamate + ATP <=> L-Glutamyl-tRNA(Glu) + Diphosphate + AMP glutamate and glutamine metabolism Porphyrin and chlorophyll metabolism,
Aminoacyl-tRNA biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments
    R05578 show the reaction diagram    
show all sequences6.1.1.24 glutamate-tRNAGln ligase ATP + L-glutamate + tRNAGlx = AMP + diphosphate + glutamyl-tRNAGlx glutamate and glutamine metabolism     BR44350 show the reaction diagram      
show all sequences1.2.1.16 succinate-semialdehyde dehydrogenase [NAD(P)+] succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+ glutamate and glutamine metabolism Alanine, aspartate and glutamate metabolism,
Tyrosine metabolism,
Butanoate metabolism,
Nicotinate and nicotinamide metabolism,
Metabolic pathways,
Microbial metabolism in diverse environments
4-aminobutanoate degradation III,
4-aminobutanoate degradation IV,
GABA shunt,
4-aminobutanoate degradation I,
L-glutamate degradation IV
BR29388_WOP show the reaction diagram R00713 show the reaction diagram RXN0-5293_WOP show the reaction diagram,
SUCCINATE-SEMIALDEHYDE-DEHYDROGENASE-RXN show the reaction diagram
1085
show all sequences1.2.1.24 succinate-semialdehyde dehydrogenase (NAD+) succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+ glutamate and glutamine metabolism Alanine, aspartate and glutamate metabolism,
Tyrosine metabolism,
Butanoate metabolism,
Nicotinate and nicotinamide metabolism,
Metabolic pathways,
Microbial metabolism in diverse environments
4-aminobutanoate degradation III,
4-aminobutanoate degradation IV,
GABA shunt,
4-aminobutanoate degradation I,
L-glutamate degradation IV
BR29388_WOP show the reaction diagram R00713 show the reaction diagram RXN0-5293_WOP show the reaction diagram,
SUCCINATE-SEMIALDEHYDE-DEHYDROGENASE-RXN show the reaction diagram
1085
show all sequences1.2.1.26 2,5-dioxovalerate dehydrogenase succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+ glutamate and glutamine metabolism Alanine, aspartate and glutamate metabolism,
Tyrosine metabolism,
Butanoate metabolism,
Nicotinate and nicotinamide metabolism,
Metabolic pathways,
Microbial metabolism in diverse environments
4-aminobutanoate degradation III,
4-aminobutanoate degradation IV,
GABA shunt,
4-aminobutanoate degradation I,
L-glutamate degradation IV
BR29388_WOP show the reaction diagram R00713 show the reaction diagram RXN0-5293_WOP show the reaction diagram,
SUCCINATE-SEMIALDEHYDE-DEHYDROGENASE-RXN show the reaction diagram
1085
show all sequences1.2.1.3 aldehyde dehydrogenase (NAD+) succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+ glutamate and glutamine metabolism Alanine, aspartate and glutamate metabolism,
Tyrosine metabolism,
Butanoate metabolism,
Nicotinate and nicotinamide metabolism,
Metabolic pathways,
Microbial metabolism in diverse environments
4-aminobutanoate degradation III,
4-aminobutanoate degradation IV,
GABA shunt,
4-aminobutanoate degradation I,
L-glutamate degradation IV
BR29388_WOP show the reaction diagram R00713 show the reaction diagram RXN0-5293_WOP show the reaction diagram,
SUCCINATE-SEMIALDEHYDE-DEHYDROGENASE-RXN show the reaction diagram
1085
show all sequences1.2.1.88 L-glutamate gamma-semialdehyde dehydrogenase succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+ glutamate and glutamine metabolism Alanine, aspartate and glutamate metabolism,
Tyrosine metabolism,
Butanoate metabolism,
Nicotinate and nicotinamide metabolism,
Metabolic pathways,
Microbial metabolism in diverse environments
4-aminobutanoate degradation III,
4-aminobutanoate degradation IV,
GABA shunt,
4-aminobutanoate degradation I,
L-glutamate degradation IV
BR29388_WOP show the reaction diagram R00713 show the reaction diagram RXN0-5293_WOP show the reaction diagram,
SUCCINATE-SEMIALDEHYDE-DEHYDROGENASE-RXN show the reaction diagram
1085
show all sequences1.2.1.16 succinate-semialdehyde dehydrogenase [NAD(P)+] succinate semialdehyde + NADP+ + H2O = succinate + NADPH + H+ glutamate and glutamine metabolism Alanine, aspartate and glutamate metabolism,
Tyrosine metabolism,
Butanoate metabolism,
Nicotinate and nicotinamide metabolism,
Metabolic pathways,
Microbial metabolism in diverse environments
4-aminobutanoate degradation III,
4-hydroxyphenylacetate degradation,
nicotine degradation I (pyridine pathway),
4-aminobutanoate degradation II,
TCA cycle IV (2-oxoglutarate decarboxylase),
nicotine degradation II (pyrrolidine pathway)
BR29388 show the reaction diagram R00714 show the reaction diagram RXN0-5293 show the reaction diagram,
SUCCSEMIALDDEHYDROG-RXN show the reaction diagram
1086
show all sequences1.2.1.26 2,5-dioxovalerate dehydrogenase succinate semialdehyde + NADP+ + H2O = succinate + NADPH + H+ glutamate and glutamine metabolism Alanine, aspartate and glutamate metabolism,
Tyrosine metabolism,
Butanoate metabolism,
Nicotinate and nicotinamide metabolism,
Metabolic pathways,
Microbial metabolism in diverse environments
4-aminobutanoate degradation III,
4-hydroxyphenylacetate degradation,
nicotine degradation I (pyridine pathway),
4-aminobutanoate degradation II,
TCA cycle IV (2-oxoglutarate decarboxylase),
nicotine degradation II (pyrrolidine pathway)
BR29388 show the reaction diagram R00714 show the reaction diagram RXN0-5293 show the reaction diagram,
SUCCSEMIALDDEHYDROG-RXN show the reaction diagram
1086
show all sequences1.2.1.79 succinate-semialdehyde dehydrogenase (NADP+) succinate semialdehyde + NADP+ + H2O = succinate + NADPH + H+ glutamate and glutamine metabolism Alanine, aspartate and glutamate metabolism,
Tyrosine metabolism,
Butanoate metabolism,
Nicotinate and nicotinamide metabolism,
Metabolic pathways,
Microbial metabolism in diverse environments
4-aminobutanoate degradation III,
4-hydroxyphenylacetate degradation,
nicotine degradation I (pyridine pathway),
4-aminobutanoate degradation II,
TCA cycle IV (2-oxoglutarate decarboxylase),
nicotine degradation II (pyrrolidine pathway)
BR29388 show the reaction diagram R00714 show the reaction diagram RXN0-5293 show the reaction diagram,
SUCCSEMIALDDEHYDROG-RXN show the reaction diagram
1086
show all sequences1.1.1.21 aldehyde reductase succinate semialdehyde + NADP+ + H2O = succinate + NADPH + H+ glutamate and glutamine metabolism Alanine, aspartate and glutamate metabolism,
Tyrosine metabolism,
Butanoate metabolism,
Nicotinate and nicotinamide metabolism,
Metabolic pathways,
Microbial metabolism in diverse environments
4-aminobutanoate degradation III,
4-hydroxyphenylacetate degradation,
nicotine degradation I (pyridine pathway),
4-aminobutanoate degradation II,
TCA cycle IV (2-oxoglutarate decarboxylase),
nicotine degradation II (pyrrolidine pathway)
BR29388 show the reaction diagram R00714 show the reaction diagram RXN0-5293 show the reaction diagram,
SUCCSEMIALDDEHYDROG-RXN show the reaction diagram
1086
show all sequences6.3.1.2 glutamine synthetase ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine glutamate and glutamine metabolism Arginine biosynthesis,
Alanine, aspartate and glutamate metabolism,
Glyoxylate and dicarboxylate metabolism,
Nitrogen metabolism,
Metabolic pathways,
Microbial metabolism in diverse environments,
Biosynthesis of amino acids
ammonia assimilation cycle I,
nitrate reduction V (assimilatory),
nitrate reduction VI (assimilatory),
ammonia assimilation cycle II,
L-glutamine biosynthesis I,
L-glutamine biosynthesis III,
nitrate reduction II (assimilatory)
BR6443 show the reaction diagram R00253 show the reaction diagram GLUTAMINESYN-RXN show the reaction diagram 760
1.1.1.-   4-hydroxybutanoate + NADP+ = succinate semialdehyde + NADPH + H+ glutamate and glutamine metabolism Butanoate metabolism,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism
3-hydroxypropanoate/4-hydroxybutanate cycle,
crotonyl-CoA/ethylmalonyl-CoA/hydroxybutyryl-CoA cycle (engineered),
L-glutamate degradation IV
BR51069 show the reaction diagram R09281 show the reaction diagram RXN-11002 show the reaction diagram 10705
show all sequences1.1.1.2 alcohol dehydrogenase (NADP+) 4-hydroxybutanoate + NADP+ = succinate semialdehyde + NADPH + H+ glutamate and glutamine metabolism Butanoate metabolism,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism
3-hydroxypropanoate/4-hydroxybutanate cycle,
crotonyl-CoA/ethylmalonyl-CoA/hydroxybutyryl-CoA cycle (engineered),
L-glutamate degradation IV
BR51069 show the reaction diagram R09281 show the reaction diagram RXN-11002 show the reaction diagram 10705
show all sequences1.1.1.B47 succinate semialdehyde reductase (NADPH) 4-hydroxybutanoate + NADP+ = succinate semialdehyde + NADPH + H+ glutamate and glutamine metabolism Butanoate metabolism,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism
3-hydroxypropanoate/4-hydroxybutanate cycle,
crotonyl-CoA/ethylmalonyl-CoA/hydroxybutyryl-CoA cycle (engineered),
L-glutamate degradation IV
BR51069 show the reaction diagram R09281 show the reaction diagram RXN-11002 show the reaction diagram 10705
1.1.1.co   4-hydroxybutanoate + NADP+ = succinate semialdehyde + NADPH + H+ glutamate and glutamine metabolism Butanoate metabolism,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism
3-hydroxypropanoate/4-hydroxybutanate cycle,
crotonyl-CoA/ethylmalonyl-CoA/hydroxybutyryl-CoA cycle (engineered),
L-glutamate degradation IV
BR51069 show the reaction diagram R09281 show the reaction diagram RXN-11002 show the reaction diagram 10705
show all sequences4.3.1.2 methylaspartate ammonia-lyase L-threo-3-methylaspartate = mesaconate + NH3 glutamate and glutamine metabolism Glyoxylate and dicarboxylate metabolism,
C5-Branched dibasic acid metabolism,
Metabolic pathways,
Carbon metabolism
methylaspartate cycle,
L-glutamate degradation VI (to pyruvate)
BR487 show the reaction diagram,
BS368446 show the reaction diagram
R03696 show the reaction diagram METHYLASPARTATE-AMMONIA-LYASE-RXN show the reaction diagram  
4.2.1.-   (R)-2-hydroxyglutaryl-CoA = (E)-glutaconyl-CoA + H2O glutamate and glutamine metabolism Butanoate metabolism L-glutamate degradation V (via hydroxyglutarate) BR51549 show the reaction diagram R03937 show the reaction diagram RXN-1083 show the reaction diagram  
show all sequences4.2.1.167 (R)-2-hydroxyglutaryl-CoA dehydratase (R)-2-hydroxyglutaryl-CoA = (E)-glutaconyl-CoA + H2O glutamate and glutamine metabolism Butanoate metabolism L-glutamate degradation V (via hydroxyglutarate) BR51549 show the reaction diagram R03937 show the reaction diagram RXN-1083 show the reaction diagram  
show all sequences4.2.1.B26 (R)-2-hydroxyglutaryl-CoA dehydratase (R)-2-hydroxyglutaryl-CoA = (E)-glutaconyl-CoA + H2O glutamate and glutamine metabolism Butanoate metabolism L-glutamate degradation V (via hydroxyglutarate) BR51549 show the reaction diagram R03937 show the reaction diagram RXN-1083 show the reaction diagram  
show all sequences4.3.1.1 aspartate ammonia-lyase L-aspartate = fumarate + NH3 glutamate and glutamine metabolism Alanine, aspartate and glutamate metabolism,
Metabolic pathways
L-glutamate degradation II BR481 show the reaction diagram R00490 show the reaction diagram ASPARTASE-RXN show the reaction diagram 922
show all sequences5.1.1.3 glutamate racemase L-glutamate = D-glutamate glutamate and glutamine metabolism,
peptidoglycan biosynthesis
D-Glutamine and D-glutamate metabolism,
Metabolic pathways
UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing),
UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)
BR171 show the reaction diagram R00260 show the reaction diagram GLUTRACE-RXN show the reaction diagram 765
show all sequences3.5.1.111 2-oxoglutaramate amidase 2-oxoglutaramate + H2O = 2-oxoglutarate + NH3 glutamate and glutamine metabolism Alanine, aspartate and glutamate metabolism nicotine degradation I (pyridine pathway),
S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation
BR50321 show the reaction diagram R00269 show the reaction diagram RXN-13072 show the reaction diagram 771
show all sequences3.5.1.3 omega-amidase 2-oxoglutaramate + H2O = 2-oxoglutarate + NH3 glutamate and glutamine metabolism Alanine, aspartate and glutamate metabolism nicotine degradation I (pyridine pathway),
S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation
BR50321 show the reaction diagram R00269 show the reaction diagram RXN-13072 show the reaction diagram 771
show all sequences1.4.1.14 glutamate synthase (NADH) 2 L-glutamate + NAD+ = L-glutamine + 2-oxoglutarate + NADH + H+ glutamate and glutamine metabolism Alanine, aspartate and glutamate metabolism,
Nitrogen metabolism,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics
ammonia assimilation cycle I,
L-glutamate biosynthesis IV
BR36862 show the reaction diagram R00093 show the reaction diagram GLUTAMATE-SYNTHASE-NADH-RXN show the reaction diagram 675
show all sequences2.6.1.15 glutamine-pyruvate transaminase L-glutamine + pyruvate = 2-oxoglutaramate + L-alanine glutamate and glutamine metabolism Alanine, aspartate and glutamate metabolism   BR47673 show the reaction diagram R00576 show the reaction diagram GLUTAMINE--PYRUVATE-AMINOTRANSFERASE-RXN show the reaction diagram 977
show all sequences2.8.3.1 propionate CoA-transferase butyryl-CoA + acetate = acetyl-CoA + butanoate glutamate and glutamine metabolism,
butanoate fermentation
Butanoate metabolism,
Metabolic pathways
L-glutamate degradation V (via hydroxyglutarate),
4-aminobutanoate degradation V,
succinate fermentation to butanoate,
acetyl-CoA fermentation to butanoate II,
gallate degradation III (anaerobic)
BS358809 show the reaction diagram R01179 show the reaction diagram R11-RXN show the reaction diagram  
show all sequences2.8.3.14 5-hydroxypentanoate CoA-transferase butyryl-CoA + acetate = acetyl-CoA + butanoate glutamate and glutamine metabolism,
butanoate fermentation
Butanoate metabolism,
Metabolic pathways
L-glutamate degradation V (via hydroxyglutarate),
4-aminobutanoate degradation V,
succinate fermentation to butanoate,
acetyl-CoA fermentation to butanoate II,
gallate degradation III (anaerobic)
BS358809 show the reaction diagram R01179 show the reaction diagram R11-RXN show the reaction diagram  
show all sequences2.8.3.8 acetate CoA-transferase butyryl-CoA + acetate = acetyl-CoA + butanoate glutamate and glutamine metabolism,
butanoate fermentation
Butanoate metabolism,
Metabolic pathways
L-glutamate degradation V (via hydroxyglutarate),
4-aminobutanoate degradation V,
succinate fermentation to butanoate,
acetyl-CoA fermentation to butanoate II,
gallate degradation III (anaerobic)
BS358809 show the reaction diagram R01179 show the reaction diagram R11-RXN show the reaction diagram  
show all sequences1.3.1.8 acyl-CoA dehydrogenase (NADP+) crotonyl-CoA + reduced acceptor = butyryl-CoA + oxidized acceptor glutamate and glutamine metabolism     BS370908 show the reaction diagram      
show all sequences1.3.8.1 short-chain acyl-CoA dehydrogenase crotonyl-CoA + reduced acceptor = butyryl-CoA + oxidized acceptor glutamate and glutamine metabolism     BS370908 show the reaction diagram      
show all sequences2.6.1.96 4-aminobutyrate-pyruvate transaminase 4-aminobutanoate + pyruvate = succinate semialdehyde + L-alanine glutamate and glutamine metabolism Alanine, aspartate and glutamate metabolism,
Butanoate metabolism,
Metabolic pathways,
Microbial metabolism in diverse environments
4-aminobutanoate degradation IV,
L-glutamate degradation IV
BR50304 show the reaction diagram R10178 show the reaction diagram RXN-6902 show the reaction diagram  
show all sequences2.6.1.19 4-aminobutyrate-2-oxoglutarate transaminase 4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate glutamate and glutamine metabolism Alanine, aspartate and glutamate metabolism,
Butanoate metabolism,
Metabolic pathways,
Microbial metabolism in diverse environments
nicotine degradation I (pyridine pathway),
4-aminobutanoate degradation II,
4-aminobutanoate degradation V,
GABA shunt,
4-aminobutanoate degradation III,
4-aminobutanoate degradation I,
L-glutamate degradation IV
BR47437 show the reaction diagram R01648 show the reaction diagram GABATRANSAM-RXN show the reaction diagram 1785
show all sequences3.5.1.2 glutaminase L-glutamine + H2O = L-glutamate + NH3 glutamate and glutamine metabolism Arginine biosynthesis,
Alanine, aspartate and glutamate metabolism,
D-Glutamine and D-glutamate metabolism,
Metabolic pathways
L-citrulline biosynthesis,
L-glutamine degradation I
BR22683 show the reaction diagram R00256 show the reaction diagram GLUTAMIN-RXN show the reaction diagram 762
show all sequences3.5.1.38 glutamin-(asparagin-)ase L-glutamine + H2O = L-glutamate + NH3 glutamate and glutamine metabolism Arginine biosynthesis,
Alanine, aspartate and glutamate metabolism,
D-Glutamine and D-glutamate metabolism,
Metabolic pathways
L-citrulline biosynthesis,
L-glutamine degradation I
BR22683 show the reaction diagram R00256 show the reaction diagram GLUTAMIN-RXN show the reaction diagram 762
show all sequences1.4.1.13 glutamate synthase (NADPH) L-glutamine + H2O = L-glutamate + NH3 glutamate and glutamine metabolism Arginine biosynthesis,
Alanine, aspartate and glutamate metabolism,
D-Glutamine and D-glutamate metabolism,
Metabolic pathways
L-citrulline biosynthesis,
L-glutamine degradation I
BR22683 show the reaction diagram R00256 show the reaction diagram GLUTAMIN-RXN show the reaction diagram 762
show all sequences1.4.7.1 glutamate synthase (ferredoxin) L-glutamine + H2O = L-glutamate + NH3 glutamate and glutamine metabolism Arginine biosynthesis,
Alanine, aspartate and glutamate metabolism,
D-Glutamine and D-glutamate metabolism,
Metabolic pathways
L-citrulline biosynthesis,
L-glutamine degradation I
BR22683 show the reaction diagram R00256 show the reaction diagram GLUTAMIN-RXN show the reaction diagram 762
show all sequences2.4.2.14 amidophosphoribosyltransferase L-glutamine + H2O = L-glutamate + NH3 glutamate and glutamine metabolism Arginine biosynthesis,
Alanine, aspartate and glutamate metabolism,
D-Glutamine and D-glutamate metabolism,
Metabolic pathways
L-citrulline biosynthesis,
L-glutamine degradation I
BR22683 show the reaction diagram R00256 show the reaction diagram GLUTAMIN-RXN show the reaction diagram 762
show all sequences4.3.1.B2 imidazole glycerol phosphate synthase L-glutamine + H2O = L-glutamate + NH3 glutamate and glutamine metabolism Arginine biosynthesis,
Alanine, aspartate and glutamate metabolism,
D-Glutamine and D-glutamate metabolism,
Metabolic pathways
L-citrulline biosynthesis,
L-glutamine degradation I
BR22683 show the reaction diagram R00256 show the reaction diagram GLUTAMIN-RXN show the reaction diagram 762
show all sequences4.3.3.6 pyridoxal 5'-phosphate synthase (glutamine hydrolysing) L-glutamine + H2O = L-glutamate + NH3 glutamate and glutamine metabolism Arginine biosynthesis,
Alanine, aspartate and glutamate metabolism,
D-Glutamine and D-glutamate metabolism,
Metabolic pathways
L-citrulline biosynthesis,
L-glutamine degradation I
BR22683 show the reaction diagram R00256 show the reaction diagram GLUTAMIN-RXN show the reaction diagram 762
show all sequences6.3.4.2 CTP synthase (glutamine hydrolysing) L-glutamine + H2O = L-glutamate + NH3 glutamate and glutamine metabolism Arginine biosynthesis,
Alanine, aspartate and glutamate metabolism,
D-Glutamine and D-glutamate metabolism,
Metabolic pathways
L-citrulline biosynthesis,
L-glutamine degradation I
BR22683 show the reaction diagram R00256 show the reaction diagram GLUTAMIN-RXN show the reaction diagram 762
show all sequences6.3.5.2 GMP synthase (glutamine-hydrolysing) L-glutamine + H2O = L-glutamate + NH3 glutamate and glutamine metabolism Arginine biosynthesis,
Alanine, aspartate and glutamate metabolism,
D-Glutamine and D-glutamate metabolism,
Metabolic pathways
L-citrulline biosynthesis,
L-glutamine degradation I
BR22683 show the reaction diagram R00256 show the reaction diagram GLUTAMIN-RXN show the reaction diagram 762
show all sequences6.3.5.4 asparagine synthase (glutamine-hydrolysing) L-glutamine + H2O = L-glutamate + NH3 glutamate and glutamine metabolism Arginine biosynthesis,
Alanine, aspartate and glutamate metabolism,
D-Glutamine and D-glutamate metabolism,
Metabolic pathways
L-citrulline biosynthesis,
L-glutamine degradation I
BR22683 show the reaction diagram R00256 show the reaction diagram GLUTAMIN-RXN show the reaction diagram 762
show all sequences6.3.5.5 carbamoyl-phosphate synthase (glutamine-hydrolysing) L-glutamine + H2O = L-glutamate + NH3 glutamate and glutamine metabolism Arginine biosynthesis,
Alanine, aspartate and glutamate metabolism,
D-Glutamine and D-glutamate metabolism,
Metabolic pathways
L-citrulline biosynthesis,
L-glutamine degradation I
BR22683 show the reaction diagram R00256 show the reaction diagram GLUTAMIN-RXN show the reaction diagram 762
show all sequences6.3.5.7 glutaminyl-tRNA synthase (glutamine-hydrolysing) L-glutamine + H2O = L-glutamate + NH3 glutamate and glutamine metabolism Arginine biosynthesis,
Alanine, aspartate and glutamate metabolism,
D-Glutamine and D-glutamate metabolism,
Metabolic pathways
L-citrulline biosynthesis,
L-glutamine degradation I
BR22683 show the reaction diagram R00256 show the reaction diagram GLUTAMIN-RXN show the reaction diagram 762
show all sequences1.1.1.399 2-oxoglutarate reductase (R)-2-hydroxyglutarate + NAD+ = 2-oxoglutarate + NADH + H+ glutamate and glutamine metabolism   L-glutamate degradation V (via hydroxyglutarate) BR51640 show the reaction diagram R11337 show the reaction diagram KETOGLUTREDUCT-RXN show the reaction diagram  
show all sequences1.1.1.290 4-phosphoerythronate dehydrogenase 2-oxoglutarate + NAD+ = D-2-hydroxyglutaric acid + NADH + H+ glutamate and glutamine metabolism     BS424498 show the reaction diagram      
show all sequences1.4.1.13 glutamate synthase (NADPH) L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH + H+ glutamate and glutamine metabolism Arginine biosynthesis,
Alanine, aspartate and glutamate metabolism,
D-Glutamine and D-glutamate metabolism,
Nitrogen metabolism,
Metabolic pathways,
Carbon metabolism
L-ornithine biosynthesis II,
GABA shunt,
L-glutamate biosynthesis II,
L-glutamate degradation X,
partial TCA cycle (obligate autotrophs),
nitrate reduction V (assimilatory),
nitrate reduction VI (assimilatory),
L-glutamate biosynthesis III
BR36869 show the reaction diagram,
BS397591_WOP show the reaction diagram
R00248 show the reaction diagram GLUTAMATE-DEHYDROGENASE-NADP+-RXN show the reaction diagram,
GLUTDEHYD-RXN show the reaction diagram
757
show all sequences1.4.1.3 glutamate dehydrogenase [NAD(P)+] L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH + H+ glutamate and glutamine metabolism Arginine biosynthesis,
Alanine, aspartate and glutamate metabolism,
D-Glutamine and D-glutamate metabolism,
Nitrogen metabolism,
Metabolic pathways,
Carbon metabolism
L-ornithine biosynthesis II,
GABA shunt,
L-glutamate biosynthesis II,
L-glutamate degradation X,
partial TCA cycle (obligate autotrophs),
nitrate reduction V (assimilatory),
nitrate reduction VI (assimilatory),
L-glutamate biosynthesis III
BR36869 show the reaction diagram,
BS397591_WOP show the reaction diagram
R00248 show the reaction diagram GLUTAMATE-DEHYDROGENASE-NADP+-RXN show the reaction diagram,
GLUTDEHYD-RXN show the reaction diagram
757
show all sequences1.4.1.4 glutamate dehydrogenase (NADP+) L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH + H+ glutamate and glutamine metabolism Arginine biosynthesis,
Alanine, aspartate and glutamate metabolism,
D-Glutamine and D-glutamate metabolism,
Nitrogen metabolism,
Metabolic pathways,
Carbon metabolism
L-ornithine biosynthesis II,
GABA shunt,
L-glutamate biosynthesis II,
L-glutamate degradation X,
partial TCA cycle (obligate autotrophs),
nitrate reduction V (assimilatory),
nitrate reduction VI (assimilatory),
L-glutamate biosynthesis III
BR36869 show the reaction diagram,
BS397591_WOP show the reaction diagram
R00248 show the reaction diagram GLUTAMATE-DEHYDROGENASE-NADP+-RXN show the reaction diagram,
GLUTDEHYD-RXN show the reaction diagram
757
show all sequences4.1.1.70 glutaconyl-CoA decarboxylase 4-carboxybut-2-enoyl-CoA = but-2-enoyl-CoA + CO2 tryptophan metabolism,
glutamate and glutamine metabolism
Benzoate degradation,
Butanoate metabolism,
Microbial metabolism in diverse environments
crotonate fermentation (to acetate and cyclohexane carboxylate),
L-glutamate degradation V (via hydroxyglutarate),
glutaryl-CoA degradation
BR48314 show the reaction diagram R03028 show the reaction diagram GLUTACONYL-COA-DECARBOXYLASE-RXN show the reaction diagram 2878
show all sequences1.3.8.6 glutaryl-CoA dehydrogenase (ETF) 4-carboxybut-2-enoyl-CoA = but-2-enoyl-CoA + CO2 tryptophan metabolism,
glutamate and glutamine metabolism
Benzoate degradation,
Butanoate metabolism,
Microbial metabolism in diverse environments
crotonate fermentation (to acetate and cyclohexane carboxylate),
L-glutamate degradation V (via hydroxyglutarate),
glutaryl-CoA degradation
BR48314 show the reaction diagram R03028 show the reaction diagram GLUTACONYL-COA-DECARBOXYLASE-RXN show the reaction diagram 2878
show all sequences6.3.5.7 glutaminyl-tRNA synthase (glutamine-hydrolysing) Glutaminyl-tRNA + L-Glutamate + Orthophosphate + ADP <=> L-Glutamyl-tRNA(Gln) + L-Glutamine + ATP + H2O glutamate and glutamine metabolism Aminoacyl-tRNA biosynthesis,
Metabolic pathways
glutaminyl-tRNAgln biosynthesis via transamidation   R03905 show the reaction diagram 6.3.5.7-RXN show the reaction diagram 3650
show all sequences6.3.5.7 glutaminyl-tRNA synthase (glutamine-hydrolysing) ATP + L-glutamyl-tRNAGln + L-glutamine = ADP + phosphate + L-glutaminyl-tRNAGln + L-glutamate glutamate and glutamine metabolism     BR44353 show the reaction diagram      
show all sequences4.1.3.22 citramalate lyase (2S)-2-hydroxy-2-methylbutanedioate = acetate + pyruvate glutamate and glutamine metabolism C5-Branched dibasic acid metabolism L-glutamate degradation VI (to pyruvate) BR3370 show the reaction diagram R00325 show the reaction diagram CITRAMALATE-LYASE-RXN show the reaction diagram  
show all sequences2.8.3.12 glutaconate CoA-transferase acetyl-CoA + (R)-2-hydroxyglutarate = acetate + (R)-2-hydroxyglutaryl-1-CoA glutamate and glutamine metabolism   L-glutamate degradation V (via hydroxyglutarate) BS360577 show the reaction diagram   RXN-1082 show the reaction diagram  
show all sequences4.1.1.15 glutamate decarboxylase L-glutamate = 4-aminobutanoate + CO2 glutamate and glutamine metabolism Alanine, aspartate and glutamate metabolism,
Butanoate metabolism,
Metabolic pathways,
Microbial metabolism in diverse environments
L-glutamate degradation IX (via 4-aminobutanoate),
GABA shunt,
L-glutamate degradation IV
BR275 show the reaction diagram R00261 show the reaction diagram GLUTDECARBOX-RXN show the reaction diagram 766