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BRENDA KEGG MetaCyc

peptidoglycan biosynthesis (BRENDA)

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EC Number Recommended Name Reaction BRENDA Pathway Name KEGG Pathway Name MetaCyc Pathway Name Reaction ID BRENDA Reaction ID KEGG Reaction ID MetaCyc Reaction ID SABIO-RK
show all sequences6.3.2.4 D-Alanine-D-alanine ligase ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine peptidoglycan biosynthesis D-Alanine metabolism,
Peptidoglycan biosynthesis,
Metabolic pathways
UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing),
UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)
BR120 show the reaction diagram R01150 show the reaction diagram DALADALALIG-RXN show the reaction diagram 1391
show all sequences3.4.11.19 D-stereospecific aminopeptidase D-Ala-D-Ala + H2O = 2 D-Ala peptidoglycan biosynthesis   vancomycin resistance II,
vancomycin resistance I
BR48417 show the reaction diagram R07651 show the reaction diagram 3.4.13.22-RXN show the reaction diagram 7268
show all sequences3.4.13.22 D-Ala-D-Ala dipeptidase D-Ala-D-Ala + H2O = 2 D-Ala peptidoglycan biosynthesis   vancomycin resistance II,
vancomycin resistance I
BR48417 show the reaction diagram R07651 show the reaction diagram 3.4.13.22-RXN show the reaction diagram 7268
show all sequences2.7.8.13 phospho-N-acetylmuramoyl-pentapeptide-transferase UDP-N-acetylmuramoyl-pentapeptide + undecaprenyl phosphate = UMP + N-acetylmuramoyl-pentapeptide-diphosphoundecaprenol peptidoglycan biosynthesis Peptidoglycan biosynthesis peptidoglycan biosynthesis I (meso-diaminopimelate containing) BS402203 show the reaction diagram R05630 show the reaction diagram PHOSNACMURPENTATRANS-RXN show the reaction diagram  
show all sequences1.3.1.98 UDP-N-acetylmuramate dehydrogenase UDP-N-acetyl-alpha-D-muramate + NADP+ = UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine + NADPH + H+ peptidoglycan biosynthesis Amino sugar and nucleotide sugar metabolism,
Peptidoglycan biosynthesis,
Metabolic pathways
anhydromuropeptides recycling I,
UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing),
UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)
BR29223 show the reaction diagram R03192 show the reaction diagram UDPNACETYLMURAMATEDEHYDROG-RXN show the reaction diagram 3021
show all sequences2.5.1.7 UDP-N-acetylglucosamine 1-carboxyvinyltransferase phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine peptidoglycan biosynthesis Amino sugar and nucleotide sugar metabolism,
Peptidoglycan biosynthesis,
Metabolic pathways
anhydromuropeptides recycling I,
UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing),
UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)
BR47474 show the reaction diagram R00660 show the reaction diagram UDPNACETYLGLUCOSAMENOLPYRTRANS-RXN show the reaction diagram  
show all sequences2.4.1.227 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase UDP-N-acetylglucosamine + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = UDP + GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol peptidoglycan biosynthesis Peptidoglycan biosynthesis,
Metabolic pathways
peptidoglycan biosynthesis II (staphylococci),
peptidoglycan biosynthesis IV (Enterococcus faecium)
BR44201 show the reaction diagram R05662 show the reaction diagram,
R06173 show the reaction diagram
RXN-8976 show the reaction diagram  
show all sequences6.3.2.7 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase ATP + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate + L-lysine = ADP + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysine peptidoglycan biosynthesis Peptidoglycan biosynthesis,
Metabolic pathways
UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing) BR123 show the reaction diagram,
BS427396 show the reaction diagram
R02786 show the reaction diagram 6.3.2.7-RXN show the reaction diagram 2661
show all sequences5.1.1.3 glutamate racemase L-glutamate = D-glutamate glutamate and glutamine metabolism,
peptidoglycan biosynthesis
D-Glutamine and D-glutamate metabolism,
Metabolic pathways
UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing),
UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)
BR171 show the reaction diagram R00260 show the reaction diagram GLUTRACE-RXN show the reaction diagram 765
show all sequences6.3.2.9 UDP-N-acetylmuramoyl-L-alanine-D-glutamate ligase ATP + UDP-N-acetyl-alpha-D-muramoyl-L-alanine + D-glutamate = ADP + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate peptidoglycan biosynthesis D-Glutamine and D-glutamate metabolism,
Peptidoglycan biosynthesis,
Metabolic pathways
UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing),
UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)
BR125 show the reaction diagram,
BS416658 show the reaction diagram
R02783 show the reaction diagram UDP-NACMURALA-GLU-LIG-RXN show the reaction diagram 2659
show all sequences6.3.2.13 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-2,6-diaminopimelate ligase ATP + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate + meso-2,6-diaminoheptanedioate = ADP + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate peptidoglycan biosynthesis Lysine biosynthesis,
Peptidoglycan biosynthesis
UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing) BR105 show the reaction diagram,
BS369028 show the reaction diagram
R02788 show the reaction diagram UDP-NACMURALGLDAPLIG-RXN show the reaction diagram  
show all sequences6.3.2.10 UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase ATP + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimelate + D-Alanyl-D-alanine <=> ADP + Orthophosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-D-alanine peptidoglycan biosynthesis Lysine biosynthesis,
Peptidoglycan biosynthesis
UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing)   R04617 show the reaction diagram UDP-NACMURALGLDAPAALIG-RXN show the reaction diagram 4284
show all sequences2.3.2.17 N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-(N6-glycyl)-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine:glycine glycyltransferase N-acetylmuramoyl-L-alanyl-D-isoglutaminyl-L-lysyl-(N6-glycyl)-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine + 2 glycyl-tRNA = N-acetylmuramoyl-L-alanyl-D-isoglutaminyl-L-lysyl-(N6-triglycyl)-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine + 2 tRNA peptidoglycan biosynthesis     BS409925 show the reaction diagram      
show all sequences3.6.1.27 undecaprenyl-diphosphate phosphatase ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate peptidoglycan biosynthesis Peptidoglycan biosynthesis di-trans,poly-cis-undecaprenyl phosphate biosynthesis BR22817 show the reaction diagram R05627 show the reaction diagram UNDECAPRENYL-DIPHOSPHATASE-RXN show the reaction diagram 5225
show all sequences6.3.2.8 UDP-N-acetylmuramate-L-alanine ligase ATP + UDP-N-acetyl-alpha-D-muramate + L-alanine = ADP + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine peptidoglycan biosynthesis D-Glutamine and D-glutamate metabolism,
Peptidoglycan biosynthesis,
Metabolic pathways
UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing),
UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)
BR124 show the reaction diagram R03193 show the reaction diagram UDP-NACMUR-ALA-LIG-RXN show the reaction diagram  
show all sequences2.3.2.18 N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-(N6-triglycine)-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine:glycine glycyltransferase N-acetylmuramoyl-L-alanyl-D-isoglutaminyl-L-lysyl-(N6-triglycyl)-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine + 2 glycyl-tRNA = N-acetylmuramoyl-L-alanyl-D-isoglutaminyl-L-lysyl-(N6-pentaglycyl)-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine + 2 tRNA peptidoglycan biosynthesis     BS409926 show the reaction diagram