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BRENDA KEGG MetaCyc

arginine metabolism (BRENDA)

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EC Number Recommended Name Reaction BRENDA Pathway Name KEGG Pathway Name MetaCyc Pathway Name Reaction ID BRENDA Reaction ID KEGG Reaction ID MetaCyc Reaction ID SABIO-RK
    5-Amino-2-oxopentanoic acid + Urea <=> 5-Guanidino-2-oxopentanoate + H2O arginine metabolism D-Arginine and D-ornithine metabolism,
Metabolic pathways
L-arginine degradation XI   R03250 show the reaction diagram RXN-7565 show the reaction diagram  
show all sequences3.5.1.16 acetylornithine deacetylase N-acetyl-L-citrulline + H2O = L-citrulline + acetate arginine metabolism Arginine biosynthesis,
Metabolic pathways
L-arginine biosynthesis III (via N-acetyl-L-citrulline) BR48939 show the reaction diagram R09107 show the reaction diagram RXN-7933 show the reaction diagram  
show all sequences3.5.1.B4 acetylcitrulline deacetylase N-acetyl-L-citrulline + H2O = L-citrulline + acetate arginine metabolism Arginine biosynthesis,
Metabolic pathways
L-arginine biosynthesis III (via N-acetyl-L-citrulline) BR48939 show the reaction diagram R09107 show the reaction diagram RXN-7933 show the reaction diagram  
show all sequences4.3.1.12 ornithine cyclodeaminase L-ornithine = L-proline + NH3 arginine metabolism Arginine and proline metabolism,
Biosynthesis of secondary metabolites,
Biosynthesis of antibiotics,
Biosynthesis of amino acids
L-arginine degradation VII (arginase 3 pathway),
L-ornithine degradation I (L-proline biosynthesis)
BR3424 show the reaction diagram R00671 show the reaction diagram ORNITHINE-CYCLODEAMINASE-RXN show the reaction diagram 1051
show all sequences2.6.1.11 acetylornithine transaminase N2-acetyl-L-ornithine + 2-oxoglutarate = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate arginine metabolism Arginine biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Biosynthesis of antibiotics,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
L-arginine biosynthesis III (via N-acetyl-L-citrulline),
L-arginine biosynthesis II (acetyl cycle),
L-ornithine biosynthesis I
BR48055 show the reaction diagram R02283 show the reaction diagram ACETYLORNTRANSAM-RXN show the reaction diagram 2248
show all sequences1.2.1.71 succinylglutamate-semialdehyde dehydrogenase N-succinyl-L-glutamate 5-semialdehyde + NAD+ + H2O = N-succinyl-L-glutamate + NADH + H+ arginine metabolism Arginine and proline metabolism,
Metabolic pathways
L-arginine degradation II (AST pathway) BR48653 show the reaction diagram R05049 show the reaction diagram SUCCGLUALDDEHYD-RXN show the reaction diagram  
show all sequences3.5.1.14 N-acyl-aliphatic-L-amino acid amidohydrolase N2-acetyl-L-ornithine + H2O = acetate + L-ornithine arginine metabolism Arginine biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Biosynthesis of antibiotics,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
L-ornithine biosynthesis I BR19236 show the reaction diagram R00669 show the reaction diagram ACETYLORNDEACET-RXN show the reaction diagram 1049
show all sequences3.5.1.16 acetylornithine deacetylase N2-acetyl-L-ornithine + H2O = acetate + L-ornithine arginine metabolism Arginine biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Biosynthesis of antibiotics,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
L-ornithine biosynthesis I BR19236 show the reaction diagram R00669 show the reaction diagram ACETYLORNDEACET-RXN show the reaction diagram 1049
show all sequences3.5.1.17 acyl-lysine deacylase N2-acetyl-L-ornithine + H2O = acetate + L-ornithine arginine metabolism Arginine biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Biosynthesis of antibiotics,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
L-ornithine biosynthesis I BR19236 show the reaction diagram R00669 show the reaction diagram ACETYLORNDEACET-RXN show the reaction diagram 1049
show all sequences3.5.3.1 arginase L-arginine + H2O = L-ornithine + urea arginine metabolism,
urea cycle
Arginine biosynthesis,
Arginine and proline metabolism,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Biosynthesis of antibiotics,
Biosynthesis of amino acids
L-Ndelta-acetylornithine biosynthesis,
L-citrulline biosynthesis,
L-arginine degradation I (arginase pathway),
putrescine biosynthesis IV,
L-arginine degradation VII (arginase 3 pathway),
L-arginine degradation VI (arginase 2 pathway),
urea cycle
BR19260 show the reaction diagram,
BS140960 show the reaction diagram
R00551 show the reaction diagram ARGINASE-RXN show the reaction diagram 574
show all sequences3.5.3.7 guanidinobutyrase L-arginine + H2O = L-ornithine + urea arginine metabolism,
urea cycle
Arginine biosynthesis,
Arginine and proline metabolism,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Biosynthesis of antibiotics,
Biosynthesis of amino acids
L-Ndelta-acetylornithine biosynthesis,
L-citrulline biosynthesis,
L-arginine degradation I (arginase pathway),
putrescine biosynthesis IV,
L-arginine degradation VII (arginase 3 pathway),
L-arginine degradation VI (arginase 2 pathway),
urea cycle
BR19260 show the reaction diagram,
BS140960 show the reaction diagram
R00551 show the reaction diagram ARGINASE-RXN show the reaction diagram 574
show all sequences2.3.1.35 glutamate N-acetyltransferase N2-acetyl-L-ornithine + L-glutamate = L-ornithine + N-acetyl-L-glutamate arginine metabolism Arginine biosynthesis,
Metabolic pathways,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
L-arginine biosynthesis II (acetyl cycle) BR44035 show the reaction diagram R02282 show the reaction diagram GLUTAMATE-N-ACETYLTRANSFERASE-RXN show the reaction diagram 2247
show all sequences1.13.12.1 arginine 2-monooxygenase L-arginine + O2 = 4-guanidinobutanamide + CO2 + H2O arginine metabolism Arginine and proline metabolism L-arginine degradation X (arginine monooxygenase pathway) BR40466 show the reaction diagram R00559 show the reaction diagram ARGININE-2-MONOOXYGENASE-RXN show the reaction diagram  
    H+ + L-glutamate + ATP + NADPH = ADP + L-glutamate-5-semialdehyde + NADP+ + phosphate arginine metabolism,
proline metabolism
        PROLINE-MULTI show the reaction diagram  
show all sequences3.5.3.7 guanidinobutyrase 4-guanidinobutanoate + H2O = 4-aminobutanoate + urea arginine metabolism Arginine and proline metabolism,
Metabolic pathways
L-arginine degradation XII,
L-arginine degradation IX (arginine:pyruvate transaminase pathway),
L-arginine degradation VIII (arginine oxidase pathway),
L-arginine degradation X (arginine monooxygenase pathway)
BR22731 show the reaction diagram R01990 show the reaction diagram GUANIDINOBUTYRASE-RXN show the reaction diagram 2030
show all sequences6.3.4.16 carbamoyl-phosphate synthase (ammonia) 2 ATP + L-glutamine + hydrogencarbonate + H2O = 2 ADP + phosphate + L-glutamate + carbamoyl phosphate arginine metabolism Pyrimidine metabolism,
Alanine, aspartate and glutamate metabolism,
Metabolic pathways
UMP biosynthesis II,
UMP biosynthesis III,
UMP biosynthesis I,
L-arginine biosynthesis IV (archaebacteria),
L-arginine biosynthesis III (via N-acetyl-L-citrulline),
L-arginine biosynthesis II (acetyl cycle),
L-arginine biosynthesis I (via L-ornithine)
BR152 show the reaction diagram R00575 show the reaction diagram CARBPSYN-RXN show the reaction diagram 203
show all sequences6.3.5.5 carbamoyl-phosphate synthase (glutamine-hydrolysing) 2 ATP + L-glutamine + hydrogencarbonate + H2O = 2 ADP + phosphate + L-glutamate + carbamoyl phosphate arginine metabolism Pyrimidine metabolism,
Alanine, aspartate and glutamate metabolism,
Metabolic pathways
UMP biosynthesis II,
UMP biosynthesis III,
UMP biosynthesis I,
L-arginine biosynthesis IV (archaebacteria),
L-arginine biosynthesis III (via N-acetyl-L-citrulline),
L-arginine biosynthesis II (acetyl cycle),
L-arginine biosynthesis I (via L-ornithine)
BR152 show the reaction diagram R00575 show the reaction diagram CARBPSYN-RXN show the reaction diagram 203
2.6.1.-   L-arginine + 2-oxoglutarate = 2-oxo-5-guanidinopentanoate + L-glutamate arginine metabolism   3-methylarginine biosynthesis,
L-arginine degradation XI
BS356596 show the reaction diagram   RXN-7564 show the reaction diagram 13596
show all sequences2.6.1.42 branched-chain-amino-acid transaminase L-arginine + 2-oxoglutarate = 2-oxo-5-guanidinopentanoate + L-glutamate arginine metabolism   3-methylarginine biosynthesis,
L-arginine degradation XI
BS356596 show the reaction diagram   RXN-7564 show the reaction diagram 13596
    L-arginine + 2-oxoglutarate = 2-oxo-5-guanidinopentanoate + L-glutamate arginine metabolism   3-methylarginine biosynthesis,
L-arginine degradation XI
BS356596 show the reaction diagram   RXN-7564 show the reaction diagram 13596
show all sequences3.5.1.96 succinylglutamate desuccinylase N-succinyl-L-glutamate + H2O = succinate + L-glutamate arginine metabolism Arginine and proline metabolism,
Metabolic pathways
L-arginine degradation II (AST pathway) BR48702 show the reaction diagram R00411 show the reaction diagram SUCCGLUDESUCC-RXN show the reaction diagram  
show all sequences4.3.2.1 argininosuccinate lyase 2-(Nomega-L-arginino)succinate = fumarate + L-arginine urea cycle,
arginine metabolism
Arginine biosynthesis,
Alanine, aspartate and glutamate metabolism,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Biosynthesis of antibiotics,
Biosynthesis of amino acids
L-arginine biosynthesis IV (archaebacteria),
L-arginine biosynthesis III (via N-acetyl-L-citrulline),
L-arginine biosynthesis II (acetyl cycle),
L-arginine biosynthesis I (via L-ornithine),
urea cycle,
nitric oxide biosynthesis II (mammals)
BR3431 show the reaction diagram R01086 show the reaction diagram ARGSUCCINLYA-RXN show the reaction diagram 573
show all sequences1.2.1.38 N-acetyl-gamma-glutamyl-phosphate reductase N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate = N-acetyl-L-glutamyl 5-phosphate + NADPH + H+ arginine metabolism Arginine biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Biosynthesis of antibiotics,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
L-arginine biosynthesis III (via N-acetyl-L-citrulline),
L-arginine biosynthesis II (acetyl cycle),
L-ornithine biosynthesis I
BR36780 show the reaction diagram R03443 show the reaction diagram N-ACETYLGLUTPREDUCT-RXN show the reaction diagram  
show all sequences3.5.1.4 amidase 4-Guanidinobutanamide + H2O <=> 4-Guanidinobutanoate + Ammonia arginine metabolism Arginine and proline metabolism L-arginine degradation X (arginine monooxygenase pathway)   R03180 show the reaction diagram GUANIDINOBUTANAMIDE-NH3-RXN show the reaction diagram  
show all sequences4.1.1.75 5-guanidino-2-oxopentanoate decarboxylase 5-guanidino-2-oxopentanoate = 4-guanidinobutanal + CO2 arginine metabolism Arginine and proline metabolism,
Metabolic pathways
L-arginine degradation XII,
L-arginine degradation IX (arginine:pyruvate transaminase pathway),
L-arginine degradation VIII (arginine oxidase pathway)
BR336 show the reaction diagram R03178 show the reaction diagram 4.1.1.75-RXN show the reaction diagram  
show all sequences2.6.1.84 arginine-pyruvate transaminase L-arginine + pyruvate = 5-guanidino-2-oxopentanoate + L-alanine arginine metabolism Arginine and proline metabolism,
Metabolic pathways
L-arginine degradation IX (arginine:pyruvate transaminase pathway) BR48810 show the reaction diagram R08197 show the reaction diagram RXN-8956 show the reaction diagram  
show all sequences1.2.1.3 aldehyde dehydrogenase (NAD+) 4-guanidinobutanal + NAD+ + H2O = 4-guanidinobutanoate + NADH + H+ arginine metabolism Arginine and proline metabolism,
Metabolic pathways
L-arginine degradation IX (arginine:pyruvate transaminase pathway),
L-arginine degradation VIII (arginine oxidase pathway)
BR29413 show the reaction diagram R03177 show the reaction diagram 1.2.1.54-RXN show the reaction diagram 3007
show all sequences1.2.1.54 gamma-guanidinobutyraldehyde dehydrogenase 4-guanidinobutanal + NAD+ + H2O = 4-guanidinobutanoate + NADH + H+ arginine metabolism Arginine and proline metabolism,
Metabolic pathways
L-arginine degradation IX (arginine:pyruvate transaminase pathway),
L-arginine degradation VIII (arginine oxidase pathway)
BR29413 show the reaction diagram R03177 show the reaction diagram 1.2.1.54-RXN show the reaction diagram 3007
show all sequences1.14.11.41 L-arginine hydroxylase L-arginine + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-arginine + succinate + CO2 arginine metabolism   ethylene biosynthesis II (microbes) BR50571 show the reaction diagram R09363 show the reaction diagram RXN-14542 show the reaction diagram  
show all sequences6.1.1.19 arginine-tRNA ligase ATP + L-Arginine + tRNA(Arg) <=> AMP + Diphosphate + L-Arginyl-tRNA(Arg) arginine metabolism Aminoacyl-tRNA biosynthesis     R03646 show the reaction diagram    
show all sequences6.1.1.19 arginine-tRNA ligase ATP + L-arginine + tRNAArg = AMP + diphosphate + L-arginyl-tRNAArg arginine metabolism     BR49 show the reaction diagram      
show all sequences2.1.3.9 N-acetylornithine carbamoyltransferase carbamoyl phosphate + N2-acetyl-L-ornithine = phosphate + N-acetyl-L-citrulline arginine metabolism Arginine biosynthesis,
Metabolic pathways
L-arginine biosynthesis III (via N-acetyl-L-citrulline) BR48711 show the reaction diagram R07245 show the reaction diagram 2.1.3.9-RXN show the reaction diagram  
show all sequences3.5.3.15 protein-arginine deiminase L-arginine + H2O = L-citrulline + NH3 arginine metabolism Arginine biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Biosynthesis of antibiotics
L-arginine degradation V (arginine deiminase pathway),
L-proline biosynthesis II (from arginine)
BR22730 show the reaction diagram,
BS369889 show the reaction diagram
R00552 show the reaction diagram ARGININE-DEIMINASE-RXN show the reaction diagram 97
show all sequences3.5.3.6 arginine deiminase L-arginine + H2O = L-citrulline + NH3 arginine metabolism Arginine biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Biosynthesis of antibiotics
L-arginine degradation V (arginine deiminase pathway),
L-proline biosynthesis II (from arginine)
BR22730 show the reaction diagram,
BS369889 show the reaction diagram
R00552 show the reaction diagram ARGININE-DEIMINASE-RXN show the reaction diagram 97
show all sequences3.5.3.23 N-succinylarginine dihydrolase N2-succinyl-L-arginine + 2 H2O = N2-succinyl-L-ornithine + 2 NH3 + CO2 arginine metabolism Arginine and proline metabolism,
Metabolic pathways
L-arginine degradation II (AST pathway) BR48703 show the reaction diagram R04189 show the reaction diagram SUCCARGDIHYDRO-RXN show the reaction diagram  
show all sequences2.7.2.8 acetylglutamate kinase ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamyl 5-phosphate arginine metabolism Arginine biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Biosynthesis of antibiotics,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
L-arginine biosynthesis III (via N-acetyl-L-citrulline),
L-arginine biosynthesis II (acetyl cycle),
L-ornithine biosynthesis I
BR47830 show the reaction diagram R02649 show the reaction diagram ACETYLGLUTKIN-RXN show the reaction diagram 2545
show all sequences2.6.1.81 succinylornithine transaminase N2-succinyl-L-ornithine + 2-oxoglutarate = N-succinyl-L-glutamate 5-semialdehyde + L-glutamate arginine metabolism Arginine and proline metabolism,
Metabolic pathways
L-arginine degradation II (AST pathway) BR48672 show the reaction diagram R04217 show the reaction diagram SUCCORNTRANSAM-RXN show the reaction diagram