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BRENDA KEGG MetaCyc

tryptophan metabolism (BRENDA)

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EC Number Recommended Name Reaction BRENDA Pathway Name KEGG Pathway Name MetaCyc Pathway Name Reaction ID BRENDA Reaction ID KEGG Reaction ID MetaCyc Reaction ID SABIO-RK
show all sequences2.6.1.7 kynurenine-oxoglutarate transaminase L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate tryptophan metabolism Tryptophan metabolism,
Metabolic pathways
L-tryptophan degradation XI (mammalian, via kynurenine) BR47389 show the reaction diagram R01956 show the reaction diagram 2.6.1.7-RXN show the reaction diagram 2003
show all sequences4.1.1.28 aromatic-L-amino-acid decarboxylase L-Trp = Tryptamine + CO2 tryptophan metabolism Tryptophan metabolism,
Indole alkaloid biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites
indole-3-acetate biosynthesis II,
secologanin and strictosidine biosynthesis,
camptothecin biosynthesis,
L-tryptophan degradation X (mammalian, via tryptamine),
beta-carboline biosynthesis,
hydroxycinnamic acid serotonin amides biosynthesis,
L-tryptophan degradation VI (via tryptamine)
BS1370 show the reaction diagram R00685 show the reaction diagram AROMATIC-L-AMINO-ACID-DECARBOXYLASE-RXN show the reaction diagram 1065
show all sequences1.1.1.1 alcohol dehydrogenase indole-3-glycol + NAD+ = indole-3-glycol aldehyde + NADH + H+ tryptophan metabolism   L-tryptophan degradation V (side chain pathway)     RXN-5424 show the reaction diagram  
show all sequences4.1.2.8 indole-3-glycerol-phosphate lyase (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = indole + D-glyceraldehyde 3-phosphate tryptophan metabolism Phenylalanine, tyrosine and tryptophan biosynthesis,
Benzoxazinoid biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites
L-tryptophan biosynthesis,
DIBOA-glucoside biosynthesis
BR48765 show the reaction diagram,
BS368282 show the reaction diagram,
BS383209 show the reaction diagram
R02340 show the reaction diagram RXN0-2381 show the reaction diagram 9527
show all sequences4.2.1.20 tryptophan synthase (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = indole + D-glyceraldehyde 3-phosphate tryptophan metabolism Phenylalanine, tyrosine and tryptophan biosynthesis,
Benzoxazinoid biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites
L-tryptophan biosynthesis,
DIBOA-glucoside biosynthesis
BR48765 show the reaction diagram,
BS368282 show the reaction diagram,
BS383209 show the reaction diagram
R02340 show the reaction diagram RXN0-2381 show the reaction diagram 9527
show all sequences1.14.14.8 anthranilate 3-monooxygenase (FAD) anthranilate + FADH2 + O2 = 3-hydroxyanthranilate + FAD + H2O tryptophan metabolism Tryptophan metabolism anthranilate degradation IV (aerobic) BR49368 show the reaction diagram R09517 show the reaction diagram RXN-10724 show the reaction diagram  
show all sequences3.5.99.11 2-aminomuconate deaminase (2-hydroxymuconate-forming) 2-aminomuconate + H2O = (2Z,4E)-2-hydroxyhexa-2,4-dienedioate + NH3 tryptophan metabolism Tryptophan metabolism   BR51717 show the reaction diagram,
BS116425 show the reaction diagram
R03887 show the reaction diagram,
R11532 show the reaction diagram
RXN-8845 show the reaction diagram  
show all sequences3.5.99.5 2-aminomuconate deaminase 2-aminomuconate + H2O = (2Z,4E)-2-hydroxyhexa-2,4-dienedioate + NH3 tryptophan metabolism Tryptophan metabolism   BR51717 show the reaction diagram,
BS116425 show the reaction diagram
R03887 show the reaction diagram,
R11532 show the reaction diagram
RXN-8845 show the reaction diagram  
show all sequences1.13.11.6 3-hydroxyanthranilate 3,4-dioxygenase 3-hydroxyanthranilate + O2 = 2-amino-3-carboxymuconate semialdehyde tryptophan metabolism Tryptophan metabolism,
Metabolic pathways
2-nitrobenzoate degradation I,
L-tryptophan degradation XII (Geobacillus),
L-tryptophan degradation XI (mammalian, via kynurenine),
L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde
BR40468 show the reaction diagram R02665 show the reaction diagram 1.13.11.6-RXN show the reaction diagram 2561
show all sequences3.7.1.3 kynureninase 3-hydroxy-L-kynurenine + H2O = 3-hydroxyanthranilate + L-alanine tryptophan metabolism Tryptophan metabolism,
Metabolic pathways
L-tryptophan degradation XI (mammalian, via kynurenine),
L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde
BS190196 show the reaction diagram R02668 show the reaction diagram 3-HYDROXY-KYNURENINASE-RXN show the reaction diagram 12038,
2564
show all sequences1.3.8.6 glutaryl-CoA dehydrogenase (ETF) glutaryl-CoA + oxidized electron-transfer flavoprotein + H+ = crotonyl-CoA + CO2 + reduced electron-transfer flavoprotein tryptophan metabolism         GLUTARYL-COA-DEHYDROGENASE-RXN show the reaction diagram  
show all sequences2.6.1.28 tryptophan-phenylpyruvate transaminase L-tryptophan + phenylpyruvate = (indol-3-yl)pyruvate + L-phenylalanine tryptophan metabolism   terrequinone A biosynthesis,
L-tryptophan degradation VIII (to tryptophol)
BR47679 show the reaction diagram R01376 show the reaction diagram 2.6.1.28-RXN show the reaction diagram  
1.1.1.-   2-oxoadipate + NAD+ = (3E)-2-oxohex-3-enedioate + NADH + H+ tryptophan metabolism   2-amino-3-carboxymuconate semialdehyde degradation to glutaryl-CoA     2-AMINOMUCONATE-REDUCTASE-RXN show the reaction diagram  
1.5.1.-   2-Oxoadipate + Ammonia + NAD+ <=> 2-Aminomuconate + NADH + H+ + H2O tryptophan metabolism Tryptophan metabolism,
Metabolic pathways
    R01937 show the reaction diagram    
show all sequences4.1.99.1 tryptophanase L-tryptophan + H2O = indole + pyruvate + NH3 tryptophan metabolism Tryptophan metabolism   BR6438 show the reaction diagram R00673 show the reaction diagram TRYPTOPHAN-RXN show the reaction diagram 1053
show all sequences1.13.11.11 tryptophan 2,3-dioxygenase L-tryptophan + O2 = N-formyl-L-kynurenine tryptophan metabolism Tryptophan metabolism,
Metabolic pathways
3-hydroxy-4-methyl-anthranilate biosynthesis II,
3-hydroxy-4-methyl-anthranilate biosynthesis I,
L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde,
L-tryptophan degradation I (via anthranilate),
L-tryptophan degradation XI (mammalian, via kynurenine)
BR37070 show the reaction diagram,
BS380639 show the reaction diagram
R00678 show the reaction diagram RXN-8665 show the reaction diagram 1060
show all sequences1.13.11.52 indoleamine 2,3-dioxygenase L-tryptophan + O2 = N-formyl-L-kynurenine tryptophan metabolism Tryptophan metabolism,
Metabolic pathways
3-hydroxy-4-methyl-anthranilate biosynthesis II,
3-hydroxy-4-methyl-anthranilate biosynthesis I,
L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde,
L-tryptophan degradation I (via anthranilate),
L-tryptophan degradation XI (mammalian, via kynurenine)
BR37070 show the reaction diagram,
BS380639 show the reaction diagram
R00678 show the reaction diagram RXN-8665 show the reaction diagram 1060
show all sequences4.1.3.27 anthranilate synthase chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate tryptophan metabolism Phenylalanine, tyrosine and tryptophan biosynthesis,
Phenazine biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Biosynthesis of antibiotics,
Biosynthesis of amino acids
4-hydroxy-2(1H)-quinolone biosynthesis,
2-heptyl-3-hydroxy-4(1H)-quinolone biosynthesis,
L-tryptophan biosynthesis,
acridone alkaloid biosynthesis
BR3373 show the reaction diagram R00986 show the reaction diagram ANTHRANSYN-RXN show the reaction diagram 1280
show all sequences2.6.1.99 L-tryptophan-pyruvate aminotransferase L-tryptophan + pyruvate = indole-3-pyruvate + L-alanine tryptophan metabolism Tryptophan metabolism,
Metabolic pathways
indole-3-acetate biosynthesis II,
indolmycin biosynthesis,
indole-3-acetate biosynthesis I
BR50308 show the reaction diagram R10180 show the reaction diagram RXN-10139 show the reaction diagram  
show all sequences1.1.1.178 3-hydroxy-2-methylbutyryl-CoA dehydrogenase 3-hydroxybutyryl-CoA + NAD+ = acetoacetyl-CoA + NADH tryptophan metabolism     BS187430 show the reaction diagram      
show all sequences1.1.1.35 3-hydroxyacyl-CoA dehydrogenase 3-hydroxybutyryl-CoA + NAD+ = acetoacetyl-CoA + NADH tryptophan metabolism     BS187430 show the reaction diagram      
show all sequences1.2.1.5 aldehyde dehydrogenase [NAD(P)+] (indol-3-yl)acetaldehyde + NADP+ + H2O = (indol-3-yl)acetate + NADPH + H+ tryptophan metabolism   L-tryptophan degradation V (side chain pathway)     RXN-5581 show the reaction diagram  
show all sequences4.2.1.122 tryptophan synthase (indole-salvaging) L-serine + indole = L-tryptophan + H2O tryptophan metabolism Phenylalanine, tyrosine and tryptophan biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites
L-tryptophan biosynthesis BR49621 show the reaction diagram R00674 show the reaction diagram RXN0-2382 show the reaction diagram 1054
show all sequences4.2.1.20 tryptophan synthase L-serine + indole = L-tryptophan + H2O tryptophan metabolism Phenylalanine, tyrosine and tryptophan biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites
L-tryptophan biosynthesis BR49621 show the reaction diagram R00674 show the reaction diagram RXN0-2382 show the reaction diagram 1054
show all sequences2.4.2.18 anthranilate phosphoribosyltransferase N-(5-phospho-D-ribosyl)-anthranilate + diphosphate = anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate tryptophan metabolism Phenylalanine, tyrosine and tryptophan biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Biosynthesis of antibiotics,
Biosynthesis of amino acids
L-tryptophan biosynthesis BR47560 show the reaction diagram R01073 show the reaction diagram PRTRANS-RXN show the reaction diagram  
show all sequences4.1.1.43 phenylpyruvate decarboxylase 3-(indol-3-yl)pyruvate = 2-(indol-3-yl)acetaldehyde + CO2 tryptophan metabolism Tryptophan metabolism,
Metabolic pathways
indole-3-acetate biosynthesis VI (bacteria),
L-tryptophan degradation VIII (to tryptophol)
BR335 show the reaction diagram R01974 show the reaction diagram 4.1.1.74-RXN show the reaction diagram 2017
show all sequences4.1.1.74 indolepyruvate decarboxylase 3-(indol-3-yl)pyruvate = 2-(indol-3-yl)acetaldehyde + CO2 tryptophan metabolism Tryptophan metabolism,
Metabolic pathways
indole-3-acetate biosynthesis VI (bacteria),
L-tryptophan degradation VIII (to tryptophol)
BR335 show the reaction diagram R01974 show the reaction diagram 4.1.1.74-RXN show the reaction diagram 2017
show all sequences1.1.1.110 indolelactate dehydrogenase (indol-3-yl)lactate + NAD+ = (indol-3-yl)pyruvate + NADH + H+ tryptophan metabolism Tryptophan metabolism L-tryptophan degradation IV (via indole-3-lactate) BR29176 show the reaction diagram R01971 show the reaction diagram INDOLELACTATE-DEHYDROGENASE-RXN show the reaction diagram  
show all sequences3.7.1.3 kynureninase L-kynurenine + H2O = anthranilate + L-alanine tryptophan metabolism Tryptophan metabolism,
Metabolic pathways
L-tryptophan degradation XI (mammalian, via kynurenine),
L-tryptophan degradation I (via anthranilate)
BR29549 show the reaction diagram R00987 show the reaction diagram KYNURENINASE-RXN show the reaction diagram 1281
1.1.1.-   (indol-3-yl)ethanol + NADP+ = (indol-3-yl)acetaldehyde + NADPH + H+ tryptophan metabolism Tryptophan metabolism L-tryptophan degradation X (mammalian, via tryptamine),
L-tryptophan degradation V (side chain pathway)
BR29245 show the reaction diagram R02680 show the reaction diagram 1.1.1.191-RXN show the reaction diagram,
RXN-10717 show the reaction diagram,
RXN-5603 show the reaction diagram
2575
show all sequences1.1.1.191 indole-3-acetaldehyde reductase (NADPH) (indol-3-yl)ethanol + NADP+ = (indol-3-yl)acetaldehyde + NADPH + H+ tryptophan metabolism Tryptophan metabolism L-tryptophan degradation X (mammalian, via tryptamine),
L-tryptophan degradation V (side chain pathway)
BR29245 show the reaction diagram R02680 show the reaction diagram 1.1.1.191-RXN show the reaction diagram,
RXN-10717 show the reaction diagram,
RXN-5603 show the reaction diagram
2575
show all sequences1.1.1.2 alcohol dehydrogenase (NADP+) (indol-3-yl)ethanol + NADP+ = (indol-3-yl)acetaldehyde + NADPH + H+ tryptophan metabolism Tryptophan metabolism L-tryptophan degradation X (mammalian, via tryptamine),
L-tryptophan degradation V (side chain pathway)
BR29245 show the reaction diagram R02680 show the reaction diagram 1.1.1.191-RXN show the reaction diagram,
RXN-10717 show the reaction diagram,
RXN-5603 show the reaction diagram
2575
show all sequences1.1.1.21 aldehyde reductase (indol-3-yl)ethanol + NADP+ = (indol-3-yl)acetaldehyde + NADPH + H+ tryptophan metabolism Tryptophan metabolism L-tryptophan degradation X (mammalian, via tryptamine),
L-tryptophan degradation V (side chain pathway)
BR29245 show the reaction diagram R02680 show the reaction diagram 1.1.1.191-RXN show the reaction diagram,
RXN-10717 show the reaction diagram,
RXN-5603 show the reaction diagram
2575
show all sequences4.1.1.48 indole-3-glycerol-phosphate synthase 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O tryptophan metabolism Phenylalanine, tyrosine and tryptophan biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Biosynthesis of antibiotics,
Biosynthesis of amino acids
L-tryptophan biosynthesis BR307 show the reaction diagram R03508 show the reaction diagram IGPSYN-RXN show the reaction diagram  
show all sequences2.6.1.1 aspartate transaminase L-tryptophan + 2-oxoglutarate = (indol-3-yl)pyruvate + L-glutamate tryptophan metabolism Tryptophan metabolism,
Metabolic pathways
indole-3-acetate biosynthesis II,
indole-3-acetate biosynthesis VI (bacteria),
L-tryptophan degradation VIII (to tryptophol),
L-tryptophan degradation IV (via indole-3-lactate)
BR47678 show the reaction diagram R00684 show the reaction diagram TRYPTOPHAN-AMINOTRANSFERASE-RXN show the reaction diagram 1064
show all sequences2.6.1.27 tryptophan transaminase L-tryptophan + 2-oxoglutarate = (indol-3-yl)pyruvate + L-glutamate tryptophan metabolism Tryptophan metabolism,
Metabolic pathways
indole-3-acetate biosynthesis II,
indole-3-acetate biosynthesis VI (bacteria),
L-tryptophan degradation VIII (to tryptophol),
L-tryptophan degradation IV (via indole-3-lactate)
BR47678 show the reaction diagram R00684 show the reaction diagram TRYPTOPHAN-AMINOTRANSFERASE-RXN show the reaction diagram 1064
show all sequences2.6.1.42 branched-chain-amino-acid transaminase L-tryptophan + 2-oxoglutarate = (indol-3-yl)pyruvate + L-glutamate tryptophan metabolism Tryptophan metabolism,
Metabolic pathways
indole-3-acetate biosynthesis II,
indole-3-acetate biosynthesis VI (bacteria),
L-tryptophan degradation VIII (to tryptophol),
L-tryptophan degradation IV (via indole-3-lactate)
BR47678 show the reaction diagram R00684 show the reaction diagram TRYPTOPHAN-AMINOTRANSFERASE-RXN show the reaction diagram 1064
show all sequences2.6.1.5 tyrosine transaminase L-tryptophan + 2-oxoglutarate = (indol-3-yl)pyruvate + L-glutamate tryptophan metabolism Tryptophan metabolism,
Metabolic pathways
indole-3-acetate biosynthesis II,
indole-3-acetate biosynthesis VI (bacteria),
L-tryptophan degradation VIII (to tryptophol),
L-tryptophan degradation IV (via indole-3-lactate)
BR47678 show the reaction diagram R00684 show the reaction diagram TRYPTOPHAN-AMINOTRANSFERASE-RXN show the reaction diagram 1064
show all sequences2.6.1.57 aromatic-amino-acid transaminase L-tryptophan + 2-oxoglutarate = (indol-3-yl)pyruvate + L-glutamate tryptophan metabolism Tryptophan metabolism,
Metabolic pathways
indole-3-acetate biosynthesis II,
indole-3-acetate biosynthesis VI (bacteria),
L-tryptophan degradation VIII (to tryptophol),
L-tryptophan degradation IV (via indole-3-lactate)
BR47678 show the reaction diagram R00684 show the reaction diagram TRYPTOPHAN-AMINOTRANSFERASE-RXN show the reaction diagram 1064
show all sequences2.6.1.9 histidinol-phosphate transaminase L-tryptophan + 2-oxoglutarate = (indol-3-yl)pyruvate + L-glutamate tryptophan metabolism Tryptophan metabolism,
Metabolic pathways
indole-3-acetate biosynthesis II,
indole-3-acetate biosynthesis VI (bacteria),
L-tryptophan degradation VIII (to tryptophol),
L-tryptophan degradation IV (via indole-3-lactate)
BR47678 show the reaction diagram R00684 show the reaction diagram TRYPTOPHAN-AMINOTRANSFERASE-RXN show the reaction diagram 1064
show all sequences6.1.1.2 tryptophan-tRNA ligase ATP + L-tryptophan + tRNATrp = AMP + diphosphate + L-tryptophyl-tRNATrp tryptophan metabolism     BR50 show the reaction diagram      
show all sequences5.3.1.24 phosphoribosylanthranilate isomerase N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate tryptophan metabolism Phenylalanine, tyrosine and tryptophan biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Biosynthesis of antibiotics,
Biosynthesis of amino acids
L-tryptophan biosynthesis BR48377 show the reaction diagram R03509 show the reaction diagram PRAISOM-RXN show the reaction diagram  
show all sequences4.2.1.119 enoyl-CoA hydratase 2 (3R)-3-hydroxybutanoyl-CoA = crotonoyl-CoA + H2O tryptophan metabolism Glyoxylate and dicarboxylate metabolism,
Butanoate metabolism,
Microbial metabolism in diverse environments,
Carbon metabolism
ethylmalonyl-CoA pathway,
acetyl-CoA fermentation to butanoate II
BR433 show the reaction diagram,
BS18665 show the reaction diagram
R03027 show the reaction diagram,
R05595 show the reaction diagram
3-HYDROXBUTYRYL-COA-DEHYDRATASE-RXN show the reaction diagram 2877,
5195
show all sequences4.2.1.17 enoyl-CoA hydratase (3R)-3-hydroxybutanoyl-CoA = crotonoyl-CoA + H2O tryptophan metabolism Glyoxylate and dicarboxylate metabolism,
Butanoate metabolism,
Microbial metabolism in diverse environments,
Carbon metabolism
ethylmalonyl-CoA pathway,
acetyl-CoA fermentation to butanoate II
BR433 show the reaction diagram,
BS18665 show the reaction diagram
R03027 show the reaction diagram,
R05595 show the reaction diagram
3-HYDROXBUTYRYL-COA-DEHYDRATASE-RXN show the reaction diagram 2877,
5195
show all sequences4.2.1.55 3-hydroxybutyryl-CoA dehydratase (3R)-3-hydroxybutanoyl-CoA = crotonoyl-CoA + H2O tryptophan metabolism Glyoxylate and dicarboxylate metabolism,
Butanoate metabolism,
Microbial metabolism in diverse environments,
Carbon metabolism
ethylmalonyl-CoA pathway,
acetyl-CoA fermentation to butanoate II
BR433 show the reaction diagram,
BS18665 show the reaction diagram
R03027 show the reaction diagram,
R05595 show the reaction diagram
3-HYDROXBUTYRYL-COA-DEHYDRATASE-RXN show the reaction diagram 2877,
5195
show all sequences4.2.1.59 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (3R)-3-hydroxybutanoyl-CoA = crotonoyl-CoA + H2O tryptophan metabolism Glyoxylate and dicarboxylate metabolism,
Butanoate metabolism,
Microbial metabolism in diverse environments,
Carbon metabolism
ethylmalonyl-CoA pathway,
acetyl-CoA fermentation to butanoate II
BR433 show the reaction diagram,
BS18665 show the reaction diagram
R03027 show the reaction diagram,
R05595 show the reaction diagram
3-HYDROXBUTYRYL-COA-DEHYDRATASE-RXN show the reaction diagram 2877,
5195
show all sequences4.1.1.77 2-oxo-3-hexenedioate decarboxylase 4-Oxalocrotonate = 2-Oxopent-4-enoate + CO2 tryptophan metabolism Benzoate degradation,
Dioxin degradation,
Metabolic pathways,
Microbial metabolism in diverse environments,
Degradation of aromatic compounds
  BS1617 show the reaction diagram R02602 show the reaction diagram    
show all sequences1.14.13.9 kynurenine 3-monooxygenase L-kynurenine + NADPH + H+ + O2 = 3-hydroxy-L-kynurenine + NADP+ + H2O tryptophan metabolism Tryptophan metabolism,
Metabolic pathways
3-hydroxy-4-methyl-anthranilate biosynthesis II,
3-hydroxy-4-methyl-anthranilate biosynthesis I,
L-tryptophan degradation XI (mammalian, via kynurenine),
L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde
BR33724 show the reaction diagram,
BS386517 show the reaction diagram
R01960 show the reaction diagram KYNURENINE-3-MONOOXYGENASE-RXN show the reaction diagram 2007
show all sequences4.1.1.45 aminocarboxymuconate-semialdehyde decarboxylase 2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate = 2-aminomuconate semialdehyde + CO2 tryptophan metabolism Tryptophan metabolism,
Metabolic pathways
2-amino-3-carboxymuconate semialdehyde degradation to 2-oxopentenoate,
2-amino-3-carboxymuconate semialdehyde degradation to glutaryl-CoA,
2-nitrobenzoate degradation I
BR304 show the reaction diagram R04323 show the reaction diagram AMINO-CARBOXYMUCONATE-SEMIALDEHYDE-RXN show the reaction diagram  
show all sequences1.13.99.3 tryptophan 2'-dioxygenase L-tryptophan + O2 = (indol-3-yl)glycolaldehyde + CO2 + NH3 tryptophan metabolism Tryptophan metabolism   BR40460 show the reaction diagram R00681 show the reaction diagram TRYPTOPHAN-2-DIOXYGENASE-RXN show the reaction diagram  
show all sequences1.2.1.32 aminomuconate-semialdehyde dehydrogenase 2-aminomuconate 6-semialdehyde + NAD+ + H2O = 2-aminomuconate + NADH + H+ tryptophan metabolism Tryptophan metabolism,
Metabolic pathways
2-amino-3-carboxymuconate semialdehyde degradation to 2-oxopentenoate,
2-aminophenol degradation,
2-amino-3-carboxymuconate semialdehyde degradation to glutaryl-CoA,
2-nitrobenzoate degradation I
BR36778 show the reaction diagram R03889 show the reaction diagram 1.2.1.32-RXN show the reaction diagram  
SPONTANEOUS   4-(2-Aminophenyl)-2,4-dioxobutanoate <=> 4-Hydroxy-2-quinolinecarboxylic acid + H2O tryptophan metabolism Metabolic pathways L-tryptophan degradation XI (mammalian, via kynurenine)   R03445 show the reaction diagram RXN-10720 show the reaction diagram  
show all sequences4.1.1.70 glutaconyl-CoA decarboxylase 4-carboxybut-2-enoyl-CoA = but-2-enoyl-CoA + CO2 tryptophan metabolism,
glutamate and glutamine metabolism
Benzoate degradation,
Butanoate metabolism,
Microbial metabolism in diverse environments
crotonate fermentation (to acetate and cyclohexane carboxylate),
L-glutamate degradation V (via hydroxyglutarate),
glutaryl-CoA degradation
BR48314 show the reaction diagram R03028 show the reaction diagram GLUTACONYL-COA-DECARBOXYLASE-RXN show the reaction diagram 2878
show all sequences1.3.8.6 glutaryl-CoA dehydrogenase (ETF) 4-carboxybut-2-enoyl-CoA = but-2-enoyl-CoA + CO2 tryptophan metabolism,
glutamate and glutamine metabolism
Benzoate degradation,
Butanoate metabolism,
Microbial metabolism in diverse environments
crotonate fermentation (to acetate and cyclohexane carboxylate),
L-glutamate degradation V (via hydroxyglutarate),
glutaryl-CoA degradation
BR48314 show the reaction diagram R03028 show the reaction diagram GLUTACONYL-COA-DECARBOXYLASE-RXN show the reaction diagram 2878
1.1.1.-   (indol-3-yl)ethanol + NAD+ = (indol-3-yl)acetaldehyde + NADH + H+ tryptophan metabolism Tryptophan metabolism L-tryptophan degradation VIII (to tryptophol),
L-tryptophan degradation V (side chain pathway)
BR29244 show the reaction diagram R02679 show the reaction diagram 1.1.1.190-RXN show the reaction diagram,
RXN-5603_WOP show the reaction diagram
2574
show all sequences1.1.1.1 alcohol dehydrogenase (indol-3-yl)ethanol + NAD+ = (indol-3-yl)acetaldehyde + NADH + H+ tryptophan metabolism Tryptophan metabolism L-tryptophan degradation VIII (to tryptophol),
L-tryptophan degradation V (side chain pathway)
BR29244 show the reaction diagram R02679 show the reaction diagram 1.1.1.190-RXN show the reaction diagram,
RXN-5603_WOP show the reaction diagram
2574
show all sequences1.1.1.190 indole-3-acetaldehyde reductase (NADH) (indol-3-yl)ethanol + NAD+ = (indol-3-yl)acetaldehyde + NADH + H+ tryptophan metabolism Tryptophan metabolism L-tryptophan degradation VIII (to tryptophol),
L-tryptophan degradation V (side chain pathway)
BR29244 show the reaction diagram R02679 show the reaction diagram 1.1.1.190-RXN show the reaction diagram,
RXN-5603_WOP show the reaction diagram
2574
show all sequences3.5.1.9 arylformamidase N-formyl-L-kynurenine + H2O = formate + L-kynurenine tryptophan metabolism Tryptophan metabolism,
Glyoxylate and dicarboxylate metabolism,
Metabolic pathways
3-hydroxy-4-methyl-anthranilate biosynthesis II,
3-hydroxy-4-methyl-anthranilate biosynthesis I,
L-tryptophan degradation XI (mammalian, via kynurenine),
L-tryptophan degradation I (via anthranilate),
L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde
BR22715 show the reaction diagram R01959 show the reaction diagram ARYLFORMAMIDASE-RXN show the reaction diagram 2006
1.1.1.-   indole-3-ketol + NAD+ = indole-3-glyoxal + NADH + H+ tryptophan metabolism   L-tryptophan degradation V (side chain pathway)     RXN-5444 show the reaction diagram  
    glutaryl-CoA + oxidized electron-transfer flavoprotein + H+ = (E)-glutaconyl-CoA + reduced electron-transfer flavoprotein tryptophan metabolism   crotonate fermentation (to acetate and cyclohexane carboxylate),
glutaryl-CoA degradation
    GLUTARYL-COA-DEHYDROG-RXN show the reaction diagram