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BRENDA KEGG MetaCyc

(5R)-carbapenem carboxylate biosynthesis (BRENDA)

:= BRENDA, := KEGG, := MetaCyc, := SABIO-RK
:= amino acid sequences := show the reaction diagram
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check
Missing Substrate
Missing Product
Commentary
Remark
proline dehydrogenase
L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol
BR36918 show the reaction diagram
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natural substrates, generic
proline dehydrogenase (acceptor)
L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol
BR36918 show the reaction diagram
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natural substrates, generic
carboxymethylproline synthase
malonyl-CoA + (S)-1-pyrroline-5-carboxylate + H2O = CoA + (2S,5S)-5-carboxymethylproline + CO2
BR50641 show the reaction diagram
R10485 show the reaction diagram
7117
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natural substrates
carbapenam-3-carboxylate synthase
ATP + (2S,5S)-5-carboxymethylproline = AMP + diphosphate + (3S,5S)-carbapenam 3-carboxylate
BR50731 show the reaction diagram
R10556 show the reaction diagram
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natural substrates
(3S,5S)-carbapenam-3-carboxylate + 2-oxoglutarate + O2 = (5R)-carbapen-2-em-3-carboxylate + succinate + CO2 + H2O
BR50588 show the reaction diagram
R10415 show the reaction diagram
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natural substrates
(5R)-carbapenem-3-carboxylate synthase
(3S,5S)-carbapenam-3-carboxylate + 2-oxoglutarate + O2 = (5R)-carbapen-2-em-3-carboxylate + succinate + CO2 + H2O
BR50588 show the reaction diagram
R10415 show the reaction diagram
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natural substrates