Print
pyruvate, phosphate dikinase
Pathways
C4 and CAM-carbon fixation (BRENDA)
:= BRENDA, 
:= KEGG, 
:= MetaCyc, 
:= SABIO-RK
:= amino acid sequences 
:= show the reaction diagram
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check
Missing Substrate
Missing Product
Commentary
Remark
ATP + pyruvate + phosphate = AMP + phosphoenolpyruvate + diphosphate
; "show the reaction diagram")
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: multi-step reactionnatural substrates, multi-step reaction
phosphoenolpyruvate carboxylase
phosphoenolpyruvate + CO2 = phosphate + oxaloacetate
; "show the reaction diagram")
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natural substrates
malate dehydrogenase (oxaloacetate-decarboxylating)
(S)-malate + NADP+ = pyruvate + CO2 + NADPH + H+
; "show the reaction diagram")
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natural substrates
malate dehydrogenase (decarboxylating)
(S)-malate + NADP+ = pyruvate + CO2 + NADPH + H+
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natural substrates
malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)
(S)-malate + NADP+ = pyruvate + CO2 + NADPH + H+
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natural substrates
3-isopropylmalate dehydrogenase
(S)-malate + NADP+ = pyruvate + CO2 + NADPH + H+
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natural substrates
L-lactate dehydrogenase
(S)-malate + NAD+ = oxaloacetate + NADH + H+
: Citrate cycle (TCA cycle),Pyruvate metabolism,
Glyoxylate and dicarboxylate metabolism,
Methane metabolism,
Carbon fixation in photosynthetic organisms,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
Carbon metabolism
: C4 photosynthetic carbon assimilation cycle, NAD-ME type,TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase),
formaldehyde assimilation I (serine pathway),
methylaspartate cycle,
gluconeogenesis I,
superpathway of glyoxylate cycle and fatty acid degradation,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
TCA cycle III (animals),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
TCA cycle IV (2-oxoglutarate decarboxylase),
reductive TCA cycle II,
incomplete reductive TCA cycle,
reductive TCA cycle I,
gluconeogenesis III,
glyoxylate cycle,
mixed acid fermentation,
pyruvate fermentation to propanoate I,
L-aspartate degradation II
; "show the reaction diagram")
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natural substrates
D-lactate dehydrogenase
(S)-malate + NAD+ = oxaloacetate + NADH + H+
: Citrate cycle (TCA cycle),Pyruvate metabolism,
Glyoxylate and dicarboxylate metabolism,
Methane metabolism,
Carbon fixation in photosynthetic organisms,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
Carbon metabolism
: C4 photosynthetic carbon assimilation cycle, NAD-ME type,TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase),
formaldehyde assimilation I (serine pathway),
methylaspartate cycle,
gluconeogenesis I,
superpathway of glyoxylate cycle and fatty acid degradation,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
TCA cycle III (animals),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
TCA cycle IV (2-oxoglutarate decarboxylase),
reductive TCA cycle II,
incomplete reductive TCA cycle,
reductive TCA cycle I,
gluconeogenesis III,
glyoxylate cycle,
mixed acid fermentation,
pyruvate fermentation to propanoate I,
L-aspartate degradation II
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natural substrates
malate dehydrogenase [NAD(P)+]
(S)-malate + NAD+ = oxaloacetate + NADH + H+
: Citrate cycle (TCA cycle),Pyruvate metabolism,
Glyoxylate and dicarboxylate metabolism,
Methane metabolism,
Carbon fixation in photosynthetic organisms,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
Carbon metabolism
: C4 photosynthetic carbon assimilation cycle, NAD-ME type,TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase),
formaldehyde assimilation I (serine pathway),
methylaspartate cycle,
gluconeogenesis I,
superpathway of glyoxylate cycle and fatty acid degradation,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
TCA cycle III (animals),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
TCA cycle IV (2-oxoglutarate decarboxylase),
reductive TCA cycle II,
incomplete reductive TCA cycle,
reductive TCA cycle I,
gluconeogenesis III,
glyoxylate cycle,
mixed acid fermentation,
pyruvate fermentation to propanoate I,
L-aspartate degradation II
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natural substrates
L-2-hydroxycarboxylate dehydrogenase (NAD+)
(S)-malate + NAD+ = oxaloacetate + NADH + H+
: Citrate cycle (TCA cycle),Pyruvate metabolism,
Glyoxylate and dicarboxylate metabolism,
Methane metabolism,
Carbon fixation in photosynthetic organisms,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
Carbon metabolism
: C4 photosynthetic carbon assimilation cycle, NAD-ME type,TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase),
formaldehyde assimilation I (serine pathway),
methylaspartate cycle,
gluconeogenesis I,
superpathway of glyoxylate cycle and fatty acid degradation,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
TCA cycle III (animals),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
TCA cycle IV (2-oxoglutarate decarboxylase),
reductive TCA cycle II,
incomplete reductive TCA cycle,
reductive TCA cycle I,
gluconeogenesis III,
glyoxylate cycle,
mixed acid fermentation,
pyruvate fermentation to propanoate I,
L-aspartate degradation II
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natural substrates
malate dehydrogenase
(S)-malate + NAD+ = oxaloacetate + NADH + H+
: Citrate cycle (TCA cycle),Pyruvate metabolism,
Glyoxylate and dicarboxylate metabolism,
Methane metabolism,
Carbon fixation in photosynthetic organisms,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
Carbon metabolism
: C4 photosynthetic carbon assimilation cycle, NAD-ME type,TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase),
formaldehyde assimilation I (serine pathway),
methylaspartate cycle,
gluconeogenesis I,
superpathway of glyoxylate cycle and fatty acid degradation,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
TCA cycle III (animals),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
TCA cycle IV (2-oxoglutarate decarboxylase),
reductive TCA cycle II,
incomplete reductive TCA cycle,
reductive TCA cycle I,
gluconeogenesis III,
glyoxylate cycle,
mixed acid fermentation,
pyruvate fermentation to propanoate I,
L-aspartate degradation II
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natural substrates
L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]
(S)-malate + NAD+ = oxaloacetate + NADH + H+
: Citrate cycle (TCA cycle),Pyruvate metabolism,
Glyoxylate and dicarboxylate metabolism,
Methane metabolism,
Carbon fixation in photosynthetic organisms,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
Carbon metabolism
: C4 photosynthetic carbon assimilation cycle, NAD-ME type,TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase),
formaldehyde assimilation I (serine pathway),
methylaspartate cycle,
gluconeogenesis I,
superpathway of glyoxylate cycle and fatty acid degradation,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
TCA cycle III (animals),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
TCA cycle IV (2-oxoglutarate decarboxylase),
reductive TCA cycle II,
incomplete reductive TCA cycle,
reductive TCA cycle I,
gluconeogenesis III,
glyoxylate cycle,
mixed acid fermentation,
pyruvate fermentation to propanoate I,
L-aspartate degradation II
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natural substrates
malate dehydrogenase (oxaloacetate-decarboxylating)
(S)-malate + NAD+ = oxaloacetate + NADH + H+
: Citrate cycle (TCA cycle),Pyruvate metabolism,
Glyoxylate and dicarboxylate metabolism,
Methane metabolism,
Carbon fixation in photosynthetic organisms,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
Carbon metabolism
: C4 photosynthetic carbon assimilation cycle, NAD-ME type,TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase),
formaldehyde assimilation I (serine pathway),
methylaspartate cycle,
gluconeogenesis I,
superpathway of glyoxylate cycle and fatty acid degradation,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
TCA cycle III (animals),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
TCA cycle IV (2-oxoglutarate decarboxylase),
reductive TCA cycle II,
incomplete reductive TCA cycle,
reductive TCA cycle I,
gluconeogenesis III,
glyoxylate cycle,
mixed acid fermentation,
pyruvate fermentation to propanoate I,
L-aspartate degradation II
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natural substrates
hydroxypyruvate reductase
(S)-malate + NAD+ = oxaloacetate + NADH + H+
: Citrate cycle (TCA cycle),Pyruvate metabolism,
Glyoxylate and dicarboxylate metabolism,
Methane metabolism,
Carbon fixation in photosynthetic organisms,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
Carbon metabolism
: C4 photosynthetic carbon assimilation cycle, NAD-ME type,TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase),
formaldehyde assimilation I (serine pathway),
methylaspartate cycle,
gluconeogenesis I,
superpathway of glyoxylate cycle and fatty acid degradation,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
TCA cycle III (animals),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
TCA cycle IV (2-oxoglutarate decarboxylase),
reductive TCA cycle II,
incomplete reductive TCA cycle,
reductive TCA cycle I,
gluconeogenesis III,
glyoxylate cycle,
mixed acid fermentation,
pyruvate fermentation to propanoate I,
L-aspartate degradation II
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natural substrates
malate dehydrogenase (NADP+)
(S)-malate + NAD+ = oxaloacetate + NADH + H+
: Citrate cycle (TCA cycle),Pyruvate metabolism,
Glyoxylate and dicarboxylate metabolism,
Methane metabolism,
Carbon fixation in photosynthetic organisms,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
Carbon metabolism
: C4 photosynthetic carbon assimilation cycle, NAD-ME type,TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase),
formaldehyde assimilation I (serine pathway),
methylaspartate cycle,
gluconeogenesis I,
superpathway of glyoxylate cycle and fatty acid degradation,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
TCA cycle III (animals),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
TCA cycle IV (2-oxoglutarate decarboxylase),
reductive TCA cycle II,
incomplete reductive TCA cycle,
reductive TCA cycle I,
gluconeogenesis III,
glyoxylate cycle,
mixed acid fermentation,
pyruvate fermentation to propanoate I,
L-aspartate degradation II
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natural substrates
3-isopropylmalate dehydrogenase
(S)-malate + NAD+ = oxaloacetate + NADH + H+
: Citrate cycle (TCA cycle),Pyruvate metabolism,
Glyoxylate and dicarboxylate metabolism,
Methane metabolism,
Carbon fixation in photosynthetic organisms,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
Carbon metabolism
: C4 photosynthetic carbon assimilation cycle, NAD-ME type,TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase),
formaldehyde assimilation I (serine pathway),
methylaspartate cycle,
gluconeogenesis I,
superpathway of glyoxylate cycle and fatty acid degradation,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
TCA cycle III (animals),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
TCA cycle IV (2-oxoglutarate decarboxylase),
reductive TCA cycle II,
incomplete reductive TCA cycle,
reductive TCA cycle I,
gluconeogenesis III,
glyoxylate cycle,
mixed acid fermentation,
pyruvate fermentation to propanoate I,
L-aspartate degradation II
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natural substrates
phosphoglycerate dehydrogenase
(S)-malate + NAD+ = oxaloacetate + NADH + H+
: Citrate cycle (TCA cycle),Pyruvate metabolism,
Glyoxylate and dicarboxylate metabolism,
Methane metabolism,
Carbon fixation in photosynthetic organisms,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
Carbon metabolism
: C4 photosynthetic carbon assimilation cycle, NAD-ME type,TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase),
formaldehyde assimilation I (serine pathway),
methylaspartate cycle,
gluconeogenesis I,
superpathway of glyoxylate cycle and fatty acid degradation,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
TCA cycle III (animals),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
TCA cycle IV (2-oxoglutarate decarboxylase),
reductive TCA cycle II,
incomplete reductive TCA cycle,
reductive TCA cycle I,
gluconeogenesis III,
glyoxylate cycle,
mixed acid fermentation,
pyruvate fermentation to propanoate I,
L-aspartate degradation II
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natural substrates
diiodophenylpyruvate reductase
(S)-malate + NAD+ = oxaloacetate + NADH + H+
: Citrate cycle (TCA cycle),Pyruvate metabolism,
Glyoxylate and dicarboxylate metabolism,
Methane metabolism,
Carbon fixation in photosynthetic organisms,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
Carbon metabolism
: C4 photosynthetic carbon assimilation cycle, NAD-ME type,TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase),
formaldehyde assimilation I (serine pathway),
methylaspartate cycle,
gluconeogenesis I,
superpathway of glyoxylate cycle and fatty acid degradation,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
TCA cycle III (animals),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
TCA cycle IV (2-oxoglutarate decarboxylase),
reductive TCA cycle II,
incomplete reductive TCA cycle,
reductive TCA cycle I,
gluconeogenesis III,
glyoxylate cycle,
mixed acid fermentation,
pyruvate fermentation to propanoate I,
L-aspartate degradation II
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natural substrates
malate dehydrogenase [NAD(P)+]
(S)-malate + NADP+ = oxaloacetate + NADPH + H+
; "show the reaction diagram")
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natural substrates
malate dehydrogenase
(S)-malate + NADP+ = oxaloacetate + NADPH + H+
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natural substrates
L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]
(S)-malate + NADP+ = oxaloacetate + NADPH + H+
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natural substrates
glyoxylate reductase (NADP+)
(S)-malate + NADP+ = oxaloacetate + NADPH + H+
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natural substrates
hydroxypyruvate reductase
(S)-malate + NADP+ = oxaloacetate + NADPH + H+
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natural substrates
malate dehydrogenase (NADP+)
(S)-malate + NADP+ = oxaloacetate + NADPH + H+
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natural substrates
phosphoenolpyruvate carboxylase
ATP + oxaloacetate = ADP + phosphoenolpyruvate + CO2
; "show the reaction diagram")
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natural substrates
phosphoenolpyruvate carboxykinase (ATP)
ATP + oxaloacetate = ADP + phosphoenolpyruvate + CO2
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natural substrates
aspartate transaminase
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: C4 photosynthetic carbon assimilation cycle, PEPCK type,C4 photosynthetic carbon assimilation cycle, NAD-ME type,
L-aspartate degradation I,
L-asparagine degradation III (mammalian),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
L-aspartate biosynthesis,
L-glutamate degradation II,
L-aspartate degradation II
; "show the reaction diagram")
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natural substrates
4-aminobutyrate-2-oxoglutarate transaminase
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: C4 photosynthetic carbon assimilation cycle, PEPCK type,C4 photosynthetic carbon assimilation cycle, NAD-ME type,
L-aspartate degradation I,
L-asparagine degradation III (mammalian),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
L-aspartate biosynthesis,
L-glutamate degradation II,
L-aspartate degradation II
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natural substrates
alanine transaminase
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: C4 photosynthetic carbon assimilation cycle, PEPCK type,C4 photosynthetic carbon assimilation cycle, NAD-ME type,
L-aspartate degradation I,
L-asparagine degradation III (mammalian),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
L-aspartate biosynthesis,
L-glutamate degradation II,
L-aspartate degradation II
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natural substrates
2-aminoadipate transaminase
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: C4 photosynthetic carbon assimilation cycle, PEPCK type,C4 photosynthetic carbon assimilation cycle, NAD-ME type,
L-aspartate degradation I,
L-asparagine degradation III (mammalian),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
L-aspartate biosynthesis,
L-glutamate degradation II,
L-aspartate degradation II
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natural substrates
branched-chain-amino-acid transaminase
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: C4 photosynthetic carbon assimilation cycle, PEPCK type,C4 photosynthetic carbon assimilation cycle, NAD-ME type,
L-aspartate degradation I,
L-asparagine degradation III (mammalian),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
L-aspartate biosynthesis,
L-glutamate degradation II,
L-aspartate degradation II
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natural substrates
tyrosine transaminase
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: C4 photosynthetic carbon assimilation cycle, PEPCK type,C4 photosynthetic carbon assimilation cycle, NAD-ME type,
L-aspartate degradation I,
L-asparagine degradation III (mammalian),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
L-aspartate biosynthesis,
L-glutamate degradation II,
L-aspartate degradation II
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natural substrates
aromatic-amino-acid transaminase
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: C4 photosynthetic carbon assimilation cycle, PEPCK type,C4 photosynthetic carbon assimilation cycle, NAD-ME type,
L-aspartate degradation I,
L-asparagine degradation III (mammalian),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
L-aspartate biosynthesis,
L-glutamate degradation II,
L-aspartate degradation II
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natural substrates
cysteine-conjugate transaminase
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: C4 photosynthetic carbon assimilation cycle, PEPCK type,C4 photosynthetic carbon assimilation cycle, NAD-ME type,
L-aspartate degradation I,
L-asparagine degradation III (mammalian),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
L-aspartate biosynthesis,
L-glutamate degradation II,
L-aspartate degradation II
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natural substrates
aspartate-prephenate aminotransferase
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: C4 photosynthetic carbon assimilation cycle, PEPCK type,C4 photosynthetic carbon assimilation cycle, NAD-ME type,
L-aspartate degradation I,
L-asparagine degradation III (mammalian),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
L-aspartate biosynthesis,
L-glutamate degradation II,
L-aspartate degradation II
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natural substrates
glutamate-prephenate aminotransferase
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: C4 photosynthetic carbon assimilation cycle, PEPCK type,C4 photosynthetic carbon assimilation cycle, NAD-ME type,
L-aspartate degradation I,
L-asparagine degradation III (mammalian),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
L-aspartate biosynthesis,
L-glutamate degradation II,
L-aspartate degradation II
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natural substrates
malate dehydrogenase (oxaloacetate-decarboxylating)
(S)-malate + NAD+ = pyruvate + CO2 + NADH + H+
; "show the reaction diagram")
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-
natural substrates
malate dehydrogenase (decarboxylating)
(S)-malate + NAD+ = pyruvate + CO2 + NADH + H+
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natural substrates
malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)
(S)-malate + NAD+ = pyruvate + CO2 + NADH + H+
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natural substrates
3-isopropylmalate dehydrogenase
(S)-malate + NAD+ = pyruvate + CO2 + NADH + H+
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-
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natural substrates
meso-tartrate dehydrogenase
(S)-malate + NAD+ = pyruvate + CO2 + NADH + H+
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natural substrates
pyruvate kinase
ATP + pyruvate = ADP + phosphoenolpyruvate
: Glycolysis / Gluconeogenesis,Purine metabolism,
Pyruvate metabolism,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
Carbon metabolism,
Biosynthesis of amino acids
: glycolysis V (Pyrococcus),Entner-Doudoroff pathway I,
Entner-Doudoroff pathway III (semi-phosphorylative),
glycolysis III (from glucose),
gluconeogenesis II (Methanobacterium thermoautotrophicum),
glycerol degradation to butanol,
glycolysis I (from glucose 6-phosphate),
Bifidobacterium shunt,
heterolactic fermentation,
glycolysis II (from fructose 6-phosphate),
anaerobic energy metabolism (invertebrates, cytosol),
superpathway of glucose and xylose degradation,
Entner-Doudoroff pathway II (non-phosphorylative),
photosynthetic 3-hydroxybutanoate biosynthesis (engineered),
1-butanol autotrophic biosynthesis (engineered),
Rubisco shunt,
mixed acid fermentation,
glycolysis IV (plant cytosol)
; "show the reaction diagram")
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natural substrates
aspartate transaminase
L-alanine + 2-oxoglutarate = pyruvate + L-glutamate
; "show the reaction diagram")
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natural substrates
alanine-oxo-acid transaminase
L-alanine + 2-oxoglutarate = pyruvate + L-glutamate
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natural substrates
alanine transaminase
L-alanine + 2-oxoglutarate = pyruvate + L-glutamate
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natural substrates
2-aminoethylphosphonate-pyruvate transaminase
L-alanine + 2-oxoglutarate = pyruvate + L-glutamate
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natural substrates
2-aminoadipate transaminase
L-alanine + 2-oxoglutarate = pyruvate + L-glutamate
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natural substrates
glycine transaminase
L-alanine + 2-oxoglutarate = pyruvate + L-glutamate
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natural substrates
branched-chain-amino-acid transaminase
L-alanine + 2-oxoglutarate = pyruvate + L-glutamate
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natural substrates
tyrosine transaminase
L-alanine + 2-oxoglutarate = pyruvate + L-glutamate
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natural substrates
glutamate-prephenate aminotransferase
L-alanine + 2-oxoglutarate = pyruvate + L-glutamate
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natural substrates