Pathways

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BRENDA KEGG MetaCyc

acetyl CoA biosynthesis (BRENDA)

:= BRENDA, := KEGG, := MetaCyc, := SABIO-RK
:= amino acid sequences := show the reaction diagram
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check
Missing Substrate
Missing Product
Commentary
Remark
malonate CoA-transferase
acetyl-CoA + malonate = acetate + malonyl-CoA
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natural substrates
malonyl-S-ACP:biotin-protein carboxyltransferase
acetyl-CoA + malonate = acetate + malonyl-CoA
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natural substrates
malonate-semialdehyde dehydrogenase
3-oxopropanoate + NADP+ + H2O = malonate + NADPH + H+
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: NAD+ (see R01604)
natural substrates
succinate-semialdehyde dehydrogenase [NAD(P)+]
3-oxopropanoate + NADP+ + H2O = malonate + NADPH + H+
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: NAD+ (see R01604)
natural substrates
succinate-semialdehyde dehydrogenase (NADP+)
3-oxopropanoate + NADP+ + H2O = malonate + NADPH + H+
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: NAD+ (see R01604)
natural substrates
dihydrolipoyllysine-residue acetyltransferase
acetyl-CoA + enzyme N6-(dihydrolipoyl)lysine = CoA + enzyme N6-(S-acetyldihydrolipoyl)lysine
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: pyruvate dehydrogenase complex:dihydrolipoyllysine-residue acetyltransferase a part of multi-step reaction (see R00209, R01699+R02569+R07618) following after R01699
natural substrates, protein
pyruvate dehydrogenase system
pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2
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natural substrates, protein
pyruvate dehydrogenase (acetyl-transferring)
pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2
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natural substrates, protein
dihydrolipoyl dehydrogenase
protein N6-(dihydrolipoyl)lysine + NAD+ = protein N6-(lipoyl)lysine + NADH + H+
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: a part step of glycine cleavage system (see R01221, R03425+R04125+R03815); Oxo-acid dehydrogenase complexes, dihydrolipoyl dehydrogenase; general reaction (see R03815 and R07618)
natural substrates, multi-step reaction
acetyl-CoA hydrolase
acetyl-CoA + H2O = CoA + acetate
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natural substrates
(S)-methylmalonyl-CoA hydrolase
acetyl-CoA + H2O = CoA + acetate
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natural substrates
ADP-dependent short-chain-acyl-CoA hydrolase
acetyl-CoA + H2O = CoA + acetate
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natural substrates
palmitoyl-CoA hydrolase
acetyl-CoA + H2O = CoA + acetate
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natural substrates
acyl-CoA hydrolase
acetyl-CoA + H2O = CoA + acetate
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natural substrates
4-hydroxybenzoyl-CoA thioesterase
acetyl-CoA + H2O = CoA + acetate
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natural substrates
phenylacetyl-CoA hydrolase
acetyl-CoA + H2O = CoA + acetate
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natural substrates
fluoroacetyl-CoA thioesterase
acetyl-CoA + H2O = CoA + acetate
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natural substrates
acetyl-CoA C-acyltransferase
acetyl-CoA + H2O = CoA + acetate
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natural substrates
carboxymethylproline synthase
acetyl-CoA + H2O = CoA + acetate
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natural substrates
homoserine O-acetyltransferase
acetyl-CoA + H2O = CoA + acetate
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natural substrates
hydroxymethylglutaryl-CoA synthase
acetyl-CoA + H2O = CoA + acetate
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natural substrates
2-isopropylmalate synthase
acetyl-CoA + H2O = CoA + acetate
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natural substrates