Pathways

Filter results:
BRENDA KEGG MetaCyc

ascorbate metabolism (BRENDA)
:= BRENDA, := KEGG, := MetaCyc, := SABIO-RK
:= amino acid sequences := show the reaction diagram
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check
Missing Substrate
Missing Product
Commentary
Remark
sorbose dehydrogenase
L-sorbose + acceptor = 1-dehydro-L-sorbose + reduced acceptor
: ascorbate metabolism
: BR48862show the reaction diagram
: R09551show the reaction diagram
-
-
-
-
natural substrates, generic
L-sorbose 1-dehydrogenase
L-sorbose + acceptor = 1-dehydro-L-sorbose + reduced acceptor
: ascorbate metabolism
: BR48862show the reaction diagram
: R09551show the reaction diagram
-
-
-
-
natural substrates, generic
L-sorbosone = 2-dehydro-L-gulonolactone
: ascorbate metabolism
: L-ascorbate biosynthesis III (D-sorbitol pathway)
: BR52874show the reaction diagram
: RXN-8780show the reaction diagram
-
-
-
-
natural substrates
0.0.0.0
spontaneous reaction
L-sorbosone = 2-dehydro-L-gulonolactone
: ascorbate metabolism
: L-ascorbate biosynthesis III (D-sorbitol pathway)
: BR52874show the reaction diagram
: RXN-8780show the reaction diagram
-
-
-
-
natural substrates
D-sorbitol dehydrogenase (acceptor)
D-sorbitol + acceptor = L-sorbose + reduced acceptor
: ascorbate metabolism
: BR36751show the reaction diagram
: R01697show the reaction diagram
-
-
-
-
natural substrates, generic
3-dehydro-L-gulonate-6-phosphate decarboxylase
3-dehydro-L-gulonate 6-phosphate + H+ = L-xylulose 5-phosphate + CO2
: ascorbate metabolism
: Pentose and glucuronate interconversions,
Ascorbate and aldarate metabolism,
Metabolic pathways,
Microbial metabolism in diverse environments
: L-ascorbate degradation I (bacterial, anaerobic),
L-ascorbate degradation II (bacterial, aerobic)
: BR48551show the reaction diagram
: R07125show the reaction diagram
: RXN0-705show the reaction diagram
: 7628
-
-
-
-
natural substrates
protein-Npi-phosphohistidine-L-ascorbate phosphotransferase
[protein]-Npi-phospho-L-histidine + L-ascorbate[side 1] = [protein]-L-histidine + L-ascorbate 6-phosphate[side 2]
: ascorbate metabolism
: BR51601show the reaction diagram
-
-
-
-
natural substrates
GDP-mannose 3,5-epimerase
GDP-alpha-D-mannose = GDP-beta-L-galactose
: ascorbate metabolism
: Ascorbate and aldarate metabolism,
Amino sugar and nucleotide sugar metabolism,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Biosynthesis of cofactors,
Biosynthesis of nucleotide sugars
: extended VTC2 cycle,
GDP-L-galactose biosynthesis,
L-ascorbate biosynthesis I (plants, L-galactose pathway),
VTC2 cycle
: BR193show the reaction diagram, BS934show the reaction diagram
: R00889show the reaction diagram
: RXN-7772show the reaction diagram
: 9255
-
-
-
-
natural substrates
GDP-L-galactose/GDP-D-glucose: hexose 1-phosphate guanylyltransferase
GDP-beta-L-galactose + alpha-D-mannose 1-phosphate = beta-L-galactose 1-phosphate + GDP-alpha-D-mannose
: ascorbate metabolism
: Ascorbate and aldarate metabolism,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Biosynthesis of cofactors
: VTC2 cycle
: BR49007show the reaction diagram
: R07678show the reaction diagram
: RXN4FS-12show the reaction diagram
-
-
-
-
natural substrates
L-galactose 1-phosphate phosphatase
L-galactose 1-phosphate + H2O = L-galactose + phosphate
: ascorbate metabolism
: Ascorbate and aldarate metabolism,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Biosynthesis of cofactors
: L-ascorbate biosynthesis I (plants, L-galactose pathway)
: BR49908show the reaction diagram, BR50987show the reaction diagram
: R07674show the reaction diagram
: RXNQT-4142show the reaction diagram
: 13655
-
-
-
-
natural substrates
L-galactose 1-phosphate phosphatase
L-galactose 1-phosphate + H2O = L-galactose + phosphate
: ascorbate metabolism
: Ascorbate and aldarate metabolism,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Biosynthesis of cofactors
: L-ascorbate biosynthesis I (plants, L-galactose pathway)
: BR49908show the reaction diagram, BR50987show the reaction diagram
: R07674show the reaction diagram
: RXNQT-4142show the reaction diagram
: 13655
-
-
-
-
natural substrates
D-threo-aldose 1-dehydrogenase
L-galactose + NAD+ = L-galactono-1,4-lactone + NADH + H+
: ascorbate metabolism
: Ascorbate and aldarate metabolism,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Biosynthesis of cofactors
: L-ascorbate biosynthesis I (plants, L-galactose pathway)
: BR49634show the reaction diagram
: R07675show the reaction diagram
: RXN-1884show the reaction diagram
: 11177
-
-
-
-
natural substrates
L-galactose 1-dehydrogenase
L-galactose + NAD+ = L-galactono-1,4-lactone + NADH + H+
: ascorbate metabolism
: Ascorbate and aldarate metabolism,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Biosynthesis of cofactors
: L-ascorbate biosynthesis I (plants, L-galactose pathway)
: BR49634show the reaction diagram
: R07675show the reaction diagram
: RXN-1884show the reaction diagram
: 11177
-
-
-
-
natural substrates
L-galactonolactone dehydrogenase
L-galactono-1,4-lactone + 2 ferricytochrome c = L-ascorbate + 2 ferrocytochrome c + 2 H+
: ascorbate metabolism
: Ascorbate and aldarate metabolism,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Biosynthesis of cofactors
: BR36836show the reaction diagram
: R00640show the reaction diagram
: 1026, 12316
-
-
-
: the first step of two-step reaction (see R12144, R00640+R07679)
natural substrates
GDP-mannose 3,5-epimerase
GDP-alpha-D-mannose = GDP-beta-L-gulose
: ascorbate metabolism
: Ascorbate and aldarate metabolism,
Amino sugar and nucleotide sugar metabolism,
Metabolic pathways,
Biosynthesis of nucleotide sugars
: L-ascorbate biosynthesis II (plants, L-gulose pathway)
: BR53090show the reaction diagram
: R07672show the reaction diagram
: RXN-7771show the reaction diagram
-
-
-
-
natural substrates
L-galactonolactone dehydrogenase
L-gulono-1,4-lactone + ferricytochrome c = L-ascorbate + ferrocytochrome c
: ascorbate metabolism
: BS397601show the reaction diagram
: 12317
-
-
-
-
-
gluconolactonase
L-gulono-1,4-lactone + H2O = L-gulonate
: ascorbate metabolism
: Ascorbate and aldarate metabolism,
Metabolic pathways,
Biosynthesis of cofactors
: L-ascorbate biosynthesis IV (animals, D-glucuronate pathway),
L-ascorbate biosynthesis VI (plants, myo-inositol pathway)
: BS401264show the reaction diagram
: R02933show the reaction diagram
: RXN-8783show the reaction diagram
: 2792
-
-
-
-
natural substrates
1,4-lactonase
L-gulono-1,4-lactone + H2O = L-gulonate
: ascorbate metabolism
: Ascorbate and aldarate metabolism,
Metabolic pathways,
Biosynthesis of cofactors
: L-ascorbate biosynthesis IV (animals, D-glucuronate pathway),
L-ascorbate biosynthesis VI (plants, myo-inositol pathway)
: BS401264show the reaction diagram
: R02933show the reaction diagram
: RXN-8783show the reaction diagram
: 2792
-
-
-
-
natural substrates
glucuronate reductase
L-gulonate + NADP+ = D-glucuronate + NADPH + H+
: ascorbate metabolism
: Pentose and glucuronate interconversions,
Ascorbate and aldarate metabolism,
Metabolic pathways,
Biosynthesis of cofactors
: BR29243show the reaction diagram
: R01481show the reaction diagram
: 11210
-
-
-
-
natural substrates
alcohol dehydrogenase (NADP+)
L-gulonate + NADP+ = D-glucuronate + NADPH + H+
: ascorbate metabolism
: Pentose and glucuronate interconversions,
Ascorbate and aldarate metabolism,
Metabolic pathways,
Biosynthesis of cofactors
: BR29243show the reaction diagram
: R01481show the reaction diagram
: 11210
-
-
-
-
natural substrates
glucuronolactone reductase
L-gulonate + NADP+ = D-glucuronate + NADPH + H+
: ascorbate metabolism
: Pentose and glucuronate interconversions,
Ascorbate and aldarate metabolism,
Metabolic pathways,
Biosynthesis of cofactors
: BR29243show the reaction diagram
: R01481show the reaction diagram
: 11210
-
-
-
-
natural substrates
uronate dehydrogenase
L-gulonate + NADP+ = D-glucuronate + NADPH + H+
: ascorbate metabolism
: Pentose and glucuronate interconversions,
Ascorbate and aldarate metabolism,
Metabolic pathways,
Biosynthesis of cofactors
: BR29243show the reaction diagram
: R01481show the reaction diagram
: 11210
-
-
-
-
natural substrates
aldose reductase
L-gulonate + NADP+ = D-glucuronate + NADPH + H+
: ascorbate metabolism
: Pentose and glucuronate interconversions,
Ascorbate and aldarate metabolism,
Metabolic pathways,
Biosynthesis of cofactors
: BR29243show the reaction diagram
: R01481show the reaction diagram
: 11210
-
-
-
-
natural substrates
L-gulonolactone oxidase
L-gulono-1,4-lactone + O2 = L-ascorbate + H2O2
: ascorbate metabolism
: Biosynthesis of cofactors
: BS424857show the reaction diagram
: R10053show the reaction diagram
: RXN-13689show the reaction diagram
-
-
-
: two-step reaction (see R03184+R00647)
natural substrates
UDP-glucuronate 4-epimerase
UDP-glucuronate = UDP-D-galacturonate
: ascorbate metabolism
: Ascorbate and aldarate metabolism,
Amino sugar and nucleotide sugar metabolism,
O-Antigen nucleotide sugar biosynthesis,
Metabolic pathways,
Biosynthesis of cofactors,
Biosynthesis of nucleotide sugars
: L-ascorbate biosynthesis V (euglena, D-galacturonate pathway),
UDP-alpha-D-galacturonate biosynthesis I (from UDP-D-glucuronate)
: BR200show the reaction diagram
: R01385show the reaction diagram
: UDP-GLUCURONATE-4-EPIMERASE-RXNshow the reaction diagram
: 1585
-
-
-
-
natural substrates
D-galacturonate + NADPH + H+ = L-galactonate + NADP+
: degradation of sugar acids,
ascorbate metabolism
: Pentose and glucuronate interconversions,
Ascorbate and aldarate metabolism,
Metabolic pathways,
Biosynthesis of cofactors
: BS424745show the reaction diagram
: R07676show the reaction diagram
: 10012
-
-
-
-
natural substrates
glucuronate reductase
D-galacturonate + NADPH + H+ = L-galactonate + NADP+
: degradation of sugar acids,
ascorbate metabolism
: Pentose and glucuronate interconversions,
Ascorbate and aldarate metabolism,
Metabolic pathways,
Biosynthesis of cofactors
: BS424745show the reaction diagram
: R07676show the reaction diagram
: 10012
-
-
-
-
natural substrates
alcohol dehydrogenase (NADP+)
D-galacturonate + NADPH + H+ = L-galactonate + NADP+
: degradation of sugar acids,
ascorbate metabolism
: Pentose and glucuronate interconversions,
Ascorbate and aldarate metabolism,
Metabolic pathways,
Biosynthesis of cofactors
: BS424745show the reaction diagram
: R07676show the reaction diagram
: 10012
-
-
-
-
natural substrates
uronate dehydrogenase
D-galacturonate + NADPH + H+ = L-galactonate + NADP+
: degradation of sugar acids,
ascorbate metabolism
: Pentose and glucuronate interconversions,
Ascorbate and aldarate metabolism,
Metabolic pathways,
Biosynthesis of cofactors
: BS424745show the reaction diagram
: R07676show the reaction diagram
: 10012
-
-
-
-
natural substrates
aldose reductase
D-galacturonate + NADPH + H+ = L-galactonate + NADP+
: degradation of sugar acids,
ascorbate metabolism
: Pentose and glucuronate interconversions,
Ascorbate and aldarate metabolism,
Metabolic pathways,
Biosynthesis of cofactors
: BS424745show the reaction diagram
: R07676show the reaction diagram
: 10012
-
-
-
-
natural substrates
D-galacturonate reductase
D-galacturonate + NADPH + H+ = L-galactonate + NADP+
: degradation of sugar acids,
ascorbate metabolism
: Pentose and glucuronate interconversions,
Ascorbate and aldarate metabolism,
Metabolic pathways,
Biosynthesis of cofactors
: BS424745show the reaction diagram
: R07676show the reaction diagram
: 10012
-
-
-
-
natural substrates
0.0.0.0
spontaneous reaction
L-ascorbate = L-dehydroascorbate
: ascorbate metabolism
: BR52870show the reaction diagram
-
-
-
-
natural substrates
L-ascorbate peroxidase
2 L-ascorbate + H2O2 + 2 H+ = L-ascorbate + L-dehydroascorbate + 2 H2O
: ascorbate metabolism
: L-ascorbate degradation II (bacterial, aerobic),
L-ascorbate degradation III
: BR49641show the reaction diagram
: RXN-12440show the reaction diagram
-
-
-
-
natural substrates
H2O + L-dehydroascorbate = (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate
: ascorbate metabolism
: Ascorbate and aldarate metabolism,
Metabolic pathways
: L-ascorbate degradation V,
L-ascorbate degradation II (bacterial, aerobic)
: BR52869show the reaction diagram
: R04785show the reaction diagram
: RXN-21400show the reaction diagram
-
-
-
-
natural substrates
0.0.0.0
spontaneous reaction
H2O + L-dehydroascorbate = (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate
: ascorbate metabolism
: Ascorbate and aldarate metabolism,
Metabolic pathways
: L-ascorbate degradation V,
L-ascorbate degradation II (bacterial, aerobic)
: BR52869show the reaction diagram
: R04785show the reaction diagram
: RXN-21400show the reaction diagram
-
-
-
-
natural substrates
gluconolactonase
H2O + L-dehydroascorbate = (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate
: ascorbate metabolism
: Ascorbate and aldarate metabolism,
Metabolic pathways
: L-ascorbate degradation V,
L-ascorbate degradation II (bacterial, aerobic)
: BR52869show the reaction diagram
: R04785show the reaction diagram
: RXN-21400show the reaction diagram
-
-
-
-
natural substrates
3-dehydro-L-gulonate 2-dehydrogenase
3-dehydro-L-gulonate + NAD+ = (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NADH + H+
: ascorbate metabolism
: Pentose and glucuronate interconversions,
Ascorbate and aldarate metabolism,
Metabolic pathways
: L-ascorbate degradation II (bacterial, aerobic)
: BR29197_WOPThis reaction also exists with phosphate.show the reaction diagram
: R02637show the reaction diagram
: 3-DEHYDRO-L-GULONATE-2-DEHYDROGENASE-RXN_WOPThis reaction also exists with phosphate.show the reaction diagram, RXN0-703show the reaction diagram
-
-
-
: NADP+ (see R02639)
natural substrates