Print
propionate CoA-transferase
Pathways
butanoate fermentation (BRENDA)
:= BRENDA, 
:= KEGG, 
:= MetaCyc, 
:= SABIO-RK
:= amino acid sequences 
:= show the reaction diagram
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check
Missing Substrate
Missing Product
Commentary
Remark
butyryl-CoA + acetate = acetyl-CoA + butanoate
; "show the reaction diagram")
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natural substrates
5-hydroxypentanoate CoA-transferase
butyryl-CoA + acetate = acetyl-CoA + butanoate
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natural substrates
acetate CoA-transferase
butyryl-CoA + acetate = acetyl-CoA + butanoate
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natural substrates
butyrate-acetoacetate CoA-transferase
butyryl-CoA + acetate = acetyl-CoA + butanoate
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natural substrates
3-oxoacyl-[acyl-carrier-protein] reductase
acetoacetyl-CoA + NADPH + H+ = (3R)-3-hydroxybutyryl-CoA + NADP+
; "show the reaction diagram")
; "show the reaction diagram")
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natural substrates
3-hydroxybutyryl-CoA dehydrogenase
acetoacetyl-CoA + NADPH + H+ = (3R)-3-hydroxybutyryl-CoA + NADP+
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natural substrates
acetoacetyl-CoA reductase
acetoacetyl-CoA + NADPH + H+ = (3R)-3-hydroxybutyryl-CoA + NADP+
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natural substrates
acetyl-CoA C-myristoyltransferase
2 acetyl-CoA = CoA + acetoacetyl-CoA
: Fatty acid degradation,Synthesis and degradation of ketone bodies,
Valine, leucine and isoleucine degradation,
Lysine degradation,
Benzoate degradation,
Tryptophan metabolism,
Pyruvate metabolism,
Glyoxylate and dicarboxylate metabolism,
Propanoate metabolism,
Butanoate metabolism,
Carbon fixation pathways in prokaryotes,
Terpenoid backbone biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
Fatty acid metabolism
: L-glutamate degradation V (via hydroxyglutarate),acetyl-CoA fermentation to butanoate II,
L-lysine fermentation to acetate and butanoate,
pyruvate fermentation to butanoate,
pyruvate fermentation to butanol I,
mevalonate pathway IV (archaea),
oleate beta-oxidation,
pyruvate fermentation to hexanol (engineered),
2-deoxy-D-ribose degradation II,
3-hydroxypropanoate/4-hydroxybutanate cycle,
crotonate fermentation (to acetate and cyclohexane carboxylate),
methyl tert-butyl ether degradation,
2-methylpropene degradation,
mevalonate pathway III (Thermoplasma),
mevalonate pathway I (eukaryotes and bacteria),
ethylmalonyl-CoA pathway,
glutaryl-CoA degradation,
isoprene biosynthesis II (engineered),
(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered),
pyruvate fermentation to butanol II (engineered),
isopropanol biosynthesis (engineered),
polyhydroxybutanoate biosynthesis,
pyruvate fermentation to acetone,
ketolysis,
ketogenesis,
mevalonate pathway II (haloarchaea),
acetoacetate degradation (to acetyl CoA)
; "show the reaction diagram")
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natural substrates
acetyl-CoA C-acyltransferase
2 acetyl-CoA = CoA + acetoacetyl-CoA
: Fatty acid degradation,Synthesis and degradation of ketone bodies,
Valine, leucine and isoleucine degradation,
Lysine degradation,
Benzoate degradation,
Tryptophan metabolism,
Pyruvate metabolism,
Glyoxylate and dicarboxylate metabolism,
Propanoate metabolism,
Butanoate metabolism,
Carbon fixation pathways in prokaryotes,
Terpenoid backbone biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
Fatty acid metabolism
: L-glutamate degradation V (via hydroxyglutarate),acetyl-CoA fermentation to butanoate II,
L-lysine fermentation to acetate and butanoate,
pyruvate fermentation to butanoate,
pyruvate fermentation to butanol I,
mevalonate pathway IV (archaea),
oleate beta-oxidation,
pyruvate fermentation to hexanol (engineered),
2-deoxy-D-ribose degradation II,
3-hydroxypropanoate/4-hydroxybutanate cycle,
crotonate fermentation (to acetate and cyclohexane carboxylate),
methyl tert-butyl ether degradation,
2-methylpropene degradation,
mevalonate pathway III (Thermoplasma),
mevalonate pathway I (eukaryotes and bacteria),
ethylmalonyl-CoA pathway,
glutaryl-CoA degradation,
isoprene biosynthesis II (engineered),
(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered),
pyruvate fermentation to butanol II (engineered),
isopropanol biosynthesis (engineered),
polyhydroxybutanoate biosynthesis,
pyruvate fermentation to acetone,
ketolysis,
ketogenesis,
mevalonate pathway II (haloarchaea),
acetoacetate degradation (to acetyl CoA)
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natural substrates
[acyl-carrier-protein] S-acetyltransferase
2 acetyl-CoA = CoA + acetoacetyl-CoA
: Fatty acid degradation,Synthesis and degradation of ketone bodies,
Valine, leucine and isoleucine degradation,
Lysine degradation,
Benzoate degradation,
Tryptophan metabolism,
Pyruvate metabolism,
Glyoxylate and dicarboxylate metabolism,
Propanoate metabolism,
Butanoate metabolism,
Carbon fixation pathways in prokaryotes,
Terpenoid backbone biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
Fatty acid metabolism
: L-glutamate degradation V (via hydroxyglutarate),acetyl-CoA fermentation to butanoate II,
L-lysine fermentation to acetate and butanoate,
pyruvate fermentation to butanoate,
pyruvate fermentation to butanol I,
mevalonate pathway IV (archaea),
oleate beta-oxidation,
pyruvate fermentation to hexanol (engineered),
2-deoxy-D-ribose degradation II,
3-hydroxypropanoate/4-hydroxybutanate cycle,
crotonate fermentation (to acetate and cyclohexane carboxylate),
methyl tert-butyl ether degradation,
2-methylpropene degradation,
mevalonate pathway III (Thermoplasma),
mevalonate pathway I (eukaryotes and bacteria),
ethylmalonyl-CoA pathway,
glutaryl-CoA degradation,
isoprene biosynthesis II (engineered),
(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered),
pyruvate fermentation to butanol II (engineered),
isopropanol biosynthesis (engineered),
polyhydroxybutanoate biosynthesis,
pyruvate fermentation to acetone,
ketolysis,
ketogenesis,
mevalonate pathway II (haloarchaea),
acetoacetate degradation (to acetyl CoA)
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natural substrates
acetyl-CoA C-acetyltransferase
2 acetyl-CoA = CoA + acetoacetyl-CoA
: Fatty acid degradation,Synthesis and degradation of ketone bodies,
Valine, leucine and isoleucine degradation,
Lysine degradation,
Benzoate degradation,
Tryptophan metabolism,
Pyruvate metabolism,
Glyoxylate and dicarboxylate metabolism,
Propanoate metabolism,
Butanoate metabolism,
Carbon fixation pathways in prokaryotes,
Terpenoid backbone biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
Fatty acid metabolism
: L-glutamate degradation V (via hydroxyglutarate),acetyl-CoA fermentation to butanoate II,
L-lysine fermentation to acetate and butanoate,
pyruvate fermentation to butanoate,
pyruvate fermentation to butanol I,
mevalonate pathway IV (archaea),
oleate beta-oxidation,
pyruvate fermentation to hexanol (engineered),
2-deoxy-D-ribose degradation II,
3-hydroxypropanoate/4-hydroxybutanate cycle,
crotonate fermentation (to acetate and cyclohexane carboxylate),
methyl tert-butyl ether degradation,
2-methylpropene degradation,
mevalonate pathway III (Thermoplasma),
mevalonate pathway I (eukaryotes and bacteria),
ethylmalonyl-CoA pathway,
glutaryl-CoA degradation,
isoprene biosynthesis II (engineered),
(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered),
pyruvate fermentation to butanol II (engineered),
isopropanol biosynthesis (engineered),
polyhydroxybutanoate biosynthesis,
pyruvate fermentation to acetone,
ketolysis,
ketogenesis,
mevalonate pathway II (haloarchaea),
acetoacetate degradation (to acetyl CoA)
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natural substrates
hydroxymethylglutaryl-CoA reductase (NADPH)
2 acetyl-CoA = CoA + acetoacetyl-CoA
: Fatty acid degradation,Synthesis and degradation of ketone bodies,
Valine, leucine and isoleucine degradation,
Lysine degradation,
Benzoate degradation,
Tryptophan metabolism,
Pyruvate metabolism,
Glyoxylate and dicarboxylate metabolism,
Propanoate metabolism,
Butanoate metabolism,
Carbon fixation pathways in prokaryotes,
Terpenoid backbone biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
Fatty acid metabolism
: L-glutamate degradation V (via hydroxyglutarate),acetyl-CoA fermentation to butanoate II,
L-lysine fermentation to acetate and butanoate,
pyruvate fermentation to butanoate,
pyruvate fermentation to butanol I,
mevalonate pathway IV (archaea),
oleate beta-oxidation,
pyruvate fermentation to hexanol (engineered),
2-deoxy-D-ribose degradation II,
3-hydroxypropanoate/4-hydroxybutanate cycle,
crotonate fermentation (to acetate and cyclohexane carboxylate),
methyl tert-butyl ether degradation,
2-methylpropene degradation,
mevalonate pathway III (Thermoplasma),
mevalonate pathway I (eukaryotes and bacteria),
ethylmalonyl-CoA pathway,
glutaryl-CoA degradation,
isoprene biosynthesis II (engineered),
(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered),
pyruvate fermentation to butanol II (engineered),
isopropanol biosynthesis (engineered),
polyhydroxybutanoate biosynthesis,
pyruvate fermentation to acetone,
ketolysis,
ketogenesis,
mevalonate pathway II (haloarchaea),
acetoacetate degradation (to acetyl CoA)
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natural substrates
acetate kinase
ATP + butanoate = ADP + butanoyl phosphate
; "show the reaction diagram")
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natural substrates
branched-chain-fatty-acid kinase
ATP + butanoate = ADP + butanoyl phosphate
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natural substrates
propionate kinase
ATP + butanoate = ADP + butanoyl phosphate
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natural substrates
butyrate kinase
ATP + butanoate = ADP + butanoyl phosphate
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natural substrates
enoyl-CoA hydratase
(3R)-3-hydroxybutanoyl-CoA = crotonoyl-CoA + H2O
; "show the reaction diagram")
; "show the reaction diagram")
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natural substrates
3-hydroxybutyryl-CoA dehydratase
(3R)-3-hydroxybutanoyl-CoA = crotonoyl-CoA + H2O
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natural substrates
3-hydroxyacyl-[acyl-carrier-protein] dehydratase
(3R)-3-hydroxybutanoyl-CoA = crotonoyl-CoA + H2O
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natural substrates
enoyl-CoA hydratase 2
(3R)-3-hydroxybutanoyl-CoA = crotonoyl-CoA + H2O
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natural substrates
short-chain-enoyl-CoA hydratase
(3R)-3-hydroxybutanoyl-CoA = crotonoyl-CoA + H2O
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natural substrates
phosphate butyryltransferase
butanoyl-CoA + phosphate = CoA + butanoyl phosphate
; "show the reaction diagram")
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natural substrates
phosphate propanoyltransferase
butanoyl-CoA + phosphate = CoA + butanoyl phosphate
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natural substrates
phosphate acetyltransferase
butanoyl-CoA + phosphate = CoA + butanoyl phosphate
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natural substrates