Pathways

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BRENDA KEGG MetaCyc

butanoate fermentation (BRENDA)
:= BRENDA, := KEGG, := MetaCyc, := SABIO-RK
:= amino acid sequences := show the reaction diagram
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check
Missing Substrate
Missing Product
Commentary
Remark
phosphate butyryltransferase
butanoyl-CoA + phosphate = CoA + butanoyl phosphate
: butanoate fermentation
: Butanoate metabolism,
Metabolic pathways
: pyruvate fermentation to butanoate
: BR44017 show the reaction diagram
: R01174 show the reaction diagram
: PHOSPHATE-BUTYRYLTRANSFERASE-RXN show the reaction diagram
: 1411
-
-
-
-
natural substrates
phosphate acetyltransferase
butanoyl-CoA + phosphate = CoA + butanoyl phosphate
: butanoate fermentation
: Butanoate metabolism,
Metabolic pathways
: pyruvate fermentation to butanoate
: BR44017 show the reaction diagram
: R01174 show the reaction diagram
: PHOSPHATE-BUTYRYLTRANSFERASE-RXN show the reaction diagram
: 1411
-
-
-
-
natural substrates
enoyl-CoA hydratase 2
(3R)-3-hydroxybutanoyl-CoA = crotonoyl-CoA + H2O
: tryptophan metabolism,
butanoate fermentation
: Glyoxylate and dicarboxylate metabolism,
Butanoate metabolism,
Microbial metabolism in diverse environments,
Carbon metabolism
: ethylmalonyl-CoA pathway,
acetyl-CoA fermentation to butanoate II
: BR433 show the reaction diagram, BS18665 show the reaction diagram
: R03027 show the reaction diagram, R05595 show the reaction diagram
: 3-HYDROXBUTYRYL-COA-DEHYDRATASE-RXN show the reaction diagram
: 2877, 5195
-
-
-
-
natural substrates
short-chain-enoyl-CoA hydratase
(3R)-3-hydroxybutanoyl-CoA = crotonoyl-CoA + H2O
: tryptophan metabolism,
butanoate fermentation
: Glyoxylate and dicarboxylate metabolism,
Butanoate metabolism,
Microbial metabolism in diverse environments,
Carbon metabolism
: ethylmalonyl-CoA pathway,
acetyl-CoA fermentation to butanoate II
: BR433 show the reaction diagram, BS18665 show the reaction diagram
: R03027 show the reaction diagram, R05595 show the reaction diagram
: 3-HYDROXBUTYRYL-COA-DEHYDRATASE-RXN show the reaction diagram
: 2877, 5195
-
-
-
-
natural substrates
enoyl-CoA hydratase
(3R)-3-hydroxybutanoyl-CoA = crotonoyl-CoA + H2O
: tryptophan metabolism,
butanoate fermentation
: Glyoxylate and dicarboxylate metabolism,
Butanoate metabolism,
Microbial metabolism in diverse environments,
Carbon metabolism
: ethylmalonyl-CoA pathway,
acetyl-CoA fermentation to butanoate II
: BR433 show the reaction diagram, BS18665 show the reaction diagram
: R03027 show the reaction diagram, R05595 show the reaction diagram
: 3-HYDROXBUTYRYL-COA-DEHYDRATASE-RXN show the reaction diagram
: 2877, 5195
-
-
-
-
natural substrates
3-hydroxybutyryl-CoA dehydratase
(3R)-3-hydroxybutanoyl-CoA = crotonoyl-CoA + H2O
: tryptophan metabolism,
butanoate fermentation
: Glyoxylate and dicarboxylate metabolism,
Butanoate metabolism,
Microbial metabolism in diverse environments,
Carbon metabolism
: ethylmalonyl-CoA pathway,
acetyl-CoA fermentation to butanoate II
: BR433 show the reaction diagram, BS18665 show the reaction diagram
: R03027 show the reaction diagram, R05595 show the reaction diagram
: 3-HYDROXBUTYRYL-COA-DEHYDRATASE-RXN show the reaction diagram
: 2877, 5195
-
-
-
-
natural substrates
3-hydroxyacyl-[acyl-carrier-protein] dehydratase
(3R)-3-hydroxybutanoyl-CoA = crotonoyl-CoA + H2O
: tryptophan metabolism,
butanoate fermentation
: Glyoxylate and dicarboxylate metabolism,
Butanoate metabolism,
Microbial metabolism in diverse environments,
Carbon metabolism
: ethylmalonyl-CoA pathway,
acetyl-CoA fermentation to butanoate II
: BR433 show the reaction diagram, BS18665 show the reaction diagram
: R03027 show the reaction diagram, R05595 show the reaction diagram
: 3-HYDROXBUTYRYL-COA-DEHYDRATASE-RXN show the reaction diagram
: 2877, 5195
-
-
-
-
natural substrates
acetate kinase
ATP + butanoate = ADP + butanoyl phosphate
: butanoate fermentation
: Butanoate metabolism,
Metabolic pathways
: pyruvate fermentation to butanoate
: BR47829 show the reaction diagram
: R01688 show the reaction diagram
: BUTYRATE-KINASE-RXN show the reaction diagram
: 1808
-
-
-
-
natural substrates
propionate kinase
ATP + butanoate = ADP + butanoyl phosphate
: butanoate fermentation
: Butanoate metabolism,
Metabolic pathways
: pyruvate fermentation to butanoate
: BR47829 show the reaction diagram
: R01688 show the reaction diagram
: BUTYRATE-KINASE-RXN show the reaction diagram
: 1808
-
-
-
-
natural substrates
butyrate kinase
ATP + butanoate = ADP + butanoyl phosphate
: butanoate fermentation
: Butanoate metabolism,
Metabolic pathways
: pyruvate fermentation to butanoate
: BR47829 show the reaction diagram
: R01688 show the reaction diagram
: BUTYRATE-KINASE-RXN show the reaction diagram
: 1808
-
-
-
-
natural substrates
3-oxoacyl-[acyl-carrier-protein] reductase
acetoacetyl-CoA + NADPH + H+ = (3R)-3-hydroxybutyryl-CoA + NADP+
: butanoate fermentation
: Glyoxylate and dicarboxylate metabolism,
Butanoate metabolism,
Microbial metabolism in diverse environments,
Carbon metabolism
: ethylmalonyl-CoA pathway,
(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered),
polyhydroxybutanoate biosynthesis,
acetyl-CoA fermentation to butanoate II
: BS188074 show the reaction diagram, BS383049 show the reaction diagram
: R01977 show the reaction diagram, R05576 show the reaction diagram
: RXN-5901 show the reaction diagram
: 5178
-
-
-
-
natural substrates
3-hydroxybutyryl-CoA dehydrogenase
acetoacetyl-CoA + NADPH + H+ = (3R)-3-hydroxybutyryl-CoA + NADP+
: butanoate fermentation
: Glyoxylate and dicarboxylate metabolism,
Butanoate metabolism,
Microbial metabolism in diverse environments,
Carbon metabolism
: ethylmalonyl-CoA pathway,
(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered),
polyhydroxybutanoate biosynthesis,
acetyl-CoA fermentation to butanoate II
: BS188074 show the reaction diagram, BS383049 show the reaction diagram
: R01977 show the reaction diagram, R05576 show the reaction diagram
: RXN-5901 show the reaction diagram
: 5178
-
-
-
-
natural substrates
acetoacetyl-CoA reductase
acetoacetyl-CoA + NADPH + H+ = (3R)-3-hydroxybutyryl-CoA + NADP+
: butanoate fermentation
: Glyoxylate and dicarboxylate metabolism,
Butanoate metabolism,
Microbial metabolism in diverse environments,
Carbon metabolism
: ethylmalonyl-CoA pathway,
(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered),
polyhydroxybutanoate biosynthesis,
acetyl-CoA fermentation to butanoate II
: BS188074 show the reaction diagram, BS383049 show the reaction diagram
: R01977 show the reaction diagram, R05576 show the reaction diagram
: RXN-5901 show the reaction diagram
: 5178
-
-
-
-
natural substrates
acetyl-CoA C-acetyltransferase
2 acetyl-CoA = CoA + acetoacetyl-CoA
: tryptophan metabolism,
mevalonate metabolism,
CO2 fixation in Crenarchaeota,
butanoate fermentation
: Fatty acid degradation,
Synthesis and degradation of ketone bodies,
Valine, leucine and isoleucine degradation,
Lysine degradation,
Benzoate degradation,
Tryptophan metabolism,
Pyruvate metabolism,
Glyoxylate and dicarboxylate metabolism,
Propanoate metabolism,
Butanoate metabolism,
Carbon fixation pathways in prokaryotes,
Terpenoid backbone biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
Carbon metabolism,
Fatty acid metabolism
: L-glutamate degradation V (via hydroxyglutarate),
3-hydroxypropanoate/4-hydroxybutanate cycle,
crotonate fermentation (to acetate and cyclohexane carboxylate),
methyl tert-butyl ether degradation,
2-methylpropene degradation,
mevalonate pathway III (archaea),
mevalonate pathway I,
ethylmalonyl-CoA pathway,
glutaryl-CoA degradation,
isoprene biosynthesis II (engineered),
(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered),
pyruvate fermentation to butanol II (engineered),
isopropanol biosynthesis (engineered),
pyruvate fermentation to hexanol (engineered),
polyhydroxybutanoate biosynthesis,
acetyl-CoA fermentation to butanoate II,
pyruvate fermentation to acetone,
pyruvate fermentation to butanoate,
pyruvate fermentation to butanol I,
ketolysis,
ketogenesis,
mevalonate pathway II (archaea),
L-lysine fermentation to acetate and butanoate,
acetoacetate degradation (to acetyl CoA)
: BR44092 show the reaction diagram
: R00238 show the reaction diagram
: ACETYL-COA-ACETYLTRANSFER-RXN show the reaction diagram
: 531
-
-
-
-
natural substrates
acetyl-CoA C-myristoyltransferase
2 acetyl-CoA = CoA + acetoacetyl-CoA
: tryptophan metabolism,
mevalonate metabolism,
CO2 fixation in Crenarchaeota,
butanoate fermentation
: Fatty acid degradation,
Synthesis and degradation of ketone bodies,
Valine, leucine and isoleucine degradation,
Lysine degradation,
Benzoate degradation,
Tryptophan metabolism,
Pyruvate metabolism,
Glyoxylate and dicarboxylate metabolism,
Propanoate metabolism,
Butanoate metabolism,
Carbon fixation pathways in prokaryotes,
Terpenoid backbone biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
Carbon metabolism,
Fatty acid metabolism
: L-glutamate degradation V (via hydroxyglutarate),
3-hydroxypropanoate/4-hydroxybutanate cycle,
crotonate fermentation (to acetate and cyclohexane carboxylate),
methyl tert-butyl ether degradation,
2-methylpropene degradation,
mevalonate pathway III (archaea),
mevalonate pathway I,
ethylmalonyl-CoA pathway,
glutaryl-CoA degradation,
isoprene biosynthesis II (engineered),
(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered),
pyruvate fermentation to butanol II (engineered),
isopropanol biosynthesis (engineered),
pyruvate fermentation to hexanol (engineered),
polyhydroxybutanoate biosynthesis,
acetyl-CoA fermentation to butanoate II,
pyruvate fermentation to acetone,
pyruvate fermentation to butanoate,
pyruvate fermentation to butanol I,
ketolysis,
ketogenesis,
mevalonate pathway II (archaea),
L-lysine fermentation to acetate and butanoate,
acetoacetate degradation (to acetyl CoA)
: BR44092 show the reaction diagram
: R00238 show the reaction diagram
: ACETYL-COA-ACETYLTRANSFER-RXN show the reaction diagram
: 531
-
-
-
-
natural substrates
acetyl-CoA C-acyltransferase
2 acetyl-CoA = CoA + acetoacetyl-CoA
: tryptophan metabolism,
mevalonate metabolism,
CO2 fixation in Crenarchaeota,
butanoate fermentation
: Fatty acid degradation,
Synthesis and degradation of ketone bodies,
Valine, leucine and isoleucine degradation,
Lysine degradation,
Benzoate degradation,
Tryptophan metabolism,
Pyruvate metabolism,
Glyoxylate and dicarboxylate metabolism,
Propanoate metabolism,
Butanoate metabolism,
Carbon fixation pathways in prokaryotes,
Terpenoid backbone biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
Carbon metabolism,
Fatty acid metabolism
: L-glutamate degradation V (via hydroxyglutarate),
3-hydroxypropanoate/4-hydroxybutanate cycle,
crotonate fermentation (to acetate and cyclohexane carboxylate),
methyl tert-butyl ether degradation,
2-methylpropene degradation,
mevalonate pathway III (archaea),
mevalonate pathway I,
ethylmalonyl-CoA pathway,
glutaryl-CoA degradation,
isoprene biosynthesis II (engineered),
(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered),
pyruvate fermentation to butanol II (engineered),
isopropanol biosynthesis (engineered),
pyruvate fermentation to hexanol (engineered),
polyhydroxybutanoate biosynthesis,
acetyl-CoA fermentation to butanoate II,
pyruvate fermentation to acetone,
pyruvate fermentation to butanoate,
pyruvate fermentation to butanol I,
ketolysis,
ketogenesis,
mevalonate pathway II (archaea),
L-lysine fermentation to acetate and butanoate,
acetoacetate degradation (to acetyl CoA)
: BR44092 show the reaction diagram
: R00238 show the reaction diagram
: ACETYL-COA-ACETYLTRANSFER-RXN show the reaction diagram
: 531
-
-
-
-
natural substrates
[acyl-carrier-protein] S-acetyltransferase
2 acetyl-CoA = CoA + acetoacetyl-CoA
: tryptophan metabolism,
mevalonate metabolism,
CO2 fixation in Crenarchaeota,
butanoate fermentation
: Fatty acid degradation,
Synthesis and degradation of ketone bodies,
Valine, leucine and isoleucine degradation,
Lysine degradation,
Benzoate degradation,
Tryptophan metabolism,
Pyruvate metabolism,
Glyoxylate and dicarboxylate metabolism,
Propanoate metabolism,
Butanoate metabolism,
Carbon fixation pathways in prokaryotes,
Terpenoid backbone biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
Carbon metabolism,
Fatty acid metabolism
: L-glutamate degradation V (via hydroxyglutarate),
3-hydroxypropanoate/4-hydroxybutanate cycle,
crotonate fermentation (to acetate and cyclohexane carboxylate),
methyl tert-butyl ether degradation,
2-methylpropene degradation,
mevalonate pathway III (archaea),
mevalonate pathway I,
ethylmalonyl-CoA pathway,
glutaryl-CoA degradation,
isoprene biosynthesis II (engineered),
(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered),
pyruvate fermentation to butanol II (engineered),
isopropanol biosynthesis (engineered),
pyruvate fermentation to hexanol (engineered),
polyhydroxybutanoate biosynthesis,
acetyl-CoA fermentation to butanoate II,
pyruvate fermentation to acetone,
pyruvate fermentation to butanoate,
pyruvate fermentation to butanol I,
ketolysis,
ketogenesis,
mevalonate pathway II (archaea),
L-lysine fermentation to acetate and butanoate,
acetoacetate degradation (to acetyl CoA)
: BR44092 show the reaction diagram
: R00238 show the reaction diagram
: ACETYL-COA-ACETYLTRANSFER-RXN show the reaction diagram
: 531
-
-
-
-
natural substrates
hydroxymethylglutaryl-CoA reductase (NADPH)
2 acetyl-CoA = CoA + acetoacetyl-CoA
: tryptophan metabolism,
mevalonate metabolism,
CO2 fixation in Crenarchaeota,
butanoate fermentation
: Fatty acid degradation,
Synthesis and degradation of ketone bodies,
Valine, leucine and isoleucine degradation,
Lysine degradation,
Benzoate degradation,
Tryptophan metabolism,
Pyruvate metabolism,
Glyoxylate and dicarboxylate metabolism,
Propanoate metabolism,
Butanoate metabolism,
Carbon fixation pathways in prokaryotes,
Terpenoid backbone biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
Carbon metabolism,
Fatty acid metabolism
: L-glutamate degradation V (via hydroxyglutarate),
3-hydroxypropanoate/4-hydroxybutanate cycle,
crotonate fermentation (to acetate and cyclohexane carboxylate),
methyl tert-butyl ether degradation,
2-methylpropene degradation,
mevalonate pathway III (archaea),
mevalonate pathway I,
ethylmalonyl-CoA pathway,
glutaryl-CoA degradation,
isoprene biosynthesis II (engineered),
(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered),
pyruvate fermentation to butanol II (engineered),
isopropanol biosynthesis (engineered),
pyruvate fermentation to hexanol (engineered),
polyhydroxybutanoate biosynthesis,
acetyl-CoA fermentation to butanoate II,
pyruvate fermentation to acetone,
pyruvate fermentation to butanoate,
pyruvate fermentation to butanol I,
ketolysis,
ketogenesis,
mevalonate pathway II (archaea),
L-lysine fermentation to acetate and butanoate,
acetoacetate degradation (to acetyl CoA)
: BR44092 show the reaction diagram
: R00238 show the reaction diagram
: ACETYL-COA-ACETYLTRANSFER-RXN show the reaction diagram
: 531
-
-
-
-
natural substrates
propionate CoA-transferase
butyryl-CoA + acetate = acetyl-CoA + butanoate
: glutamate and glutamine metabolism,
butanoate fermentation
: Butanoate metabolism,
Metabolic pathways
: L-glutamate degradation V (via hydroxyglutarate),
4-aminobutanoate degradation V,
succinate fermentation to butanoate,
acetyl-CoA fermentation to butanoate II,
gallate degradation III (anaerobic)
: BS358809 show the reaction diagram
: R01179 show the reaction diagram
: R11-RXN show the reaction diagram
-
-
-
-
natural substrates
5-hydroxypentanoate CoA-transferase
butyryl-CoA + acetate = acetyl-CoA + butanoate
: glutamate and glutamine metabolism,
butanoate fermentation
: Butanoate metabolism,
Metabolic pathways
: L-glutamate degradation V (via hydroxyglutarate),
4-aminobutanoate degradation V,
succinate fermentation to butanoate,
acetyl-CoA fermentation to butanoate II,
gallate degradation III (anaerobic)
: BS358809 show the reaction diagram
: R01179 show the reaction diagram
: R11-RXN show the reaction diagram
-
-
-
-
natural substrates
acetate CoA-transferase
butyryl-CoA + acetate = acetyl-CoA + butanoate
: glutamate and glutamine metabolism,
butanoate fermentation
: Butanoate metabolism,
Metabolic pathways
: L-glutamate degradation V (via hydroxyglutarate),
4-aminobutanoate degradation V,
succinate fermentation to butanoate,
acetyl-CoA fermentation to butanoate II,
gallate degradation III (anaerobic)
: BS358809 show the reaction diagram
: R01179 show the reaction diagram
: R11-RXN show the reaction diagram
-
-
-
-
natural substrates
butyrate-acetoacetate CoA-transferase
butyryl-CoA + acetate = acetyl-CoA + butanoate
: glutamate and glutamine metabolism,
butanoate fermentation
: Butanoate metabolism,
Metabolic pathways
: L-glutamate degradation V (via hydroxyglutarate),
4-aminobutanoate degradation V,
succinate fermentation to butanoate,
acetyl-CoA fermentation to butanoate II,
gallate degradation III (anaerobic)
: BS358809 show the reaction diagram
: R01179 show the reaction diagram
: R11-RXN show the reaction diagram
-
-
-
-
natural substrates