Pathways

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BRENDA KEGG MetaCyc

ceramide biosynthesis (BRENDA)
:= BRENDA, := KEGG, := MetaCyc, := SABIO-RK
:= amino acid sequences := show the reaction diagram
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check
Missing Substrate
Missing Product
Commentary
Remark
4-coumarate-CoA ligase
ATP + a long-chain fatty acid + CoA = AMP + diphosphate + a long-chain fatty acyl-CoA
: ceramide biosynthesis
: Fatty acid biosynthesis,
Fatty acid degradation,
Metabolic pathways,
Fatty acid metabolism
: stearate biosynthesis II (bacteria and plants),
alkane biosynthesis II,
phosphatidylcholine acyl editing,
wax esters biosynthesis II,
long chain fatty acid ester synthesis (engineered),
long-chain fatty acid activation,
stearate biosynthesis I (animals),
sphingosine and sphingosine-1-phosphate metabolism,
ceramide and sphingolipid recycling and degradation (yeast),
palmitate biosynthesis (type II fatty acid synthase)
: BR82show the reaction diagram, BS287show the reaction diagram
: R00390show the reaction diagram, R01280show the reaction diagram
: RXN-16380show the reaction diagram, RXN-7904show the reaction diagram, RXN-9623show the reaction diagram
: 10953, 1496
-
-
-
: general reaction
natural substrates
long-chain-fatty-acid-CoA ligase
ATP + a long-chain fatty acid + CoA = AMP + diphosphate + a long-chain fatty acyl-CoA
: ceramide biosynthesis
: Fatty acid biosynthesis,
Fatty acid degradation,
Metabolic pathways,
Fatty acid metabolism
: stearate biosynthesis II (bacteria and plants),
alkane biosynthesis II,
phosphatidylcholine acyl editing,
wax esters biosynthesis II,
long chain fatty acid ester synthesis (engineered),
long-chain fatty acid activation,
stearate biosynthesis I (animals),
sphingosine and sphingosine-1-phosphate metabolism,
ceramide and sphingolipid recycling and degradation (yeast),
palmitate biosynthesis (type II fatty acid synthase)
: BR82show the reaction diagram, BS287show the reaction diagram
: R00390show the reaction diagram, R01280show the reaction diagram
: RXN-16380show the reaction diagram, RXN-7904show the reaction diagram, RXN-9623show the reaction diagram
: 10953, 1496
-
-
-
: general reaction
natural substrates
phenylacetate-CoA ligase
ATP + a long-chain fatty acid + CoA = AMP + diphosphate + a long-chain fatty acyl-CoA
: ceramide biosynthesis
: Fatty acid biosynthesis,
Fatty acid degradation,
Metabolic pathways,
Fatty acid metabolism
: stearate biosynthesis II (bacteria and plants),
alkane biosynthesis II,
phosphatidylcholine acyl editing,
wax esters biosynthesis II,
long chain fatty acid ester synthesis (engineered),
long-chain fatty acid activation,
stearate biosynthesis I (animals),
sphingosine and sphingosine-1-phosphate metabolism,
ceramide and sphingolipid recycling and degradation (yeast),
palmitate biosynthesis (type II fatty acid synthase)
: BR82show the reaction diagram, BS287show the reaction diagram
: R00390show the reaction diagram, R01280show the reaction diagram
: RXN-16380show the reaction diagram, RXN-7904show the reaction diagram, RXN-9623show the reaction diagram
: 10953, 1496
-
-
-
: general reaction
natural substrates
OPC-8:CoA ligase
ATP + a long-chain fatty acid + CoA = AMP + diphosphate + a long-chain fatty acyl-CoA
: ceramide biosynthesis
: Fatty acid biosynthesis,
Fatty acid degradation,
Metabolic pathways,
Fatty acid metabolism
: stearate biosynthesis II (bacteria and plants),
alkane biosynthesis II,
phosphatidylcholine acyl editing,
wax esters biosynthesis II,
long chain fatty acid ester synthesis (engineered),
long-chain fatty acid activation,
stearate biosynthesis I (animals),
sphingosine and sphingosine-1-phosphate metabolism,
ceramide and sphingolipid recycling and degradation (yeast),
palmitate biosynthesis (type II fatty acid synthase)
: BR82show the reaction diagram, BS287show the reaction diagram
: R00390show the reaction diagram, R01280show the reaction diagram
: RXN-16380show the reaction diagram, RXN-7904show the reaction diagram, RXN-9623show the reaction diagram
: 10953, 1496
-
-
-
: general reaction
natural substrates
firefly luciferase
ATP + a long-chain fatty acid + CoA = AMP + diphosphate + a long-chain fatty acyl-CoA
: ceramide biosynthesis
: Fatty acid biosynthesis,
Fatty acid degradation,
Metabolic pathways,
Fatty acid metabolism
: stearate biosynthesis II (bacteria and plants),
alkane biosynthesis II,
phosphatidylcholine acyl editing,
wax esters biosynthesis II,
long chain fatty acid ester synthesis (engineered),
long-chain fatty acid activation,
stearate biosynthesis I (animals),
sphingosine and sphingosine-1-phosphate metabolism,
ceramide and sphingolipid recycling and degradation (yeast),
palmitate biosynthesis (type II fatty acid synthase)
: BR82show the reaction diagram, BS287show the reaction diagram
: R00390show the reaction diagram, R01280show the reaction diagram
: RXN-16380show the reaction diagram, RXN-7904show the reaction diagram, RXN-9623show the reaction diagram
: 10953, 1496
-
-
-
: general reaction
natural substrates
3-dehydrosphinganine reductase
sphinganine + NADP+ = 3-dehydrosphinganine + NADPH + H+
: ceramide biosynthesis
: Sphingolipid metabolism,
Metabolic pathways
: sphingolipid biosynthesis (yeast),
ceramide de novo biosynthesis,
sphingolipid biosynthesis (plants)
: BR29168show the reaction diagram
: R02978show the reaction diagram
: 3-DEHYDROSPHINGANINE-REDUCTASE-RXNshow the reaction diagram, RXN-20505show the reaction diagram
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natural substrates
serine C-palmitoyltransferase
palmitoyl-CoA + L-serine = CoA + 3-dehydro-D-sphinganine + CO2
: ceramide biosynthesis
: Sphingolipid metabolism,
Metabolic pathways
: sphingolipid biosynthesis (yeast),
ceramide de novo biosynthesis,
sphingolipid biosynthesis (plants)
: BR44052show the reaction diagram
: R01281show the reaction diagram
: SERINE-C-PALMITOYLTRANSFERASE-RXNshow the reaction diagram
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-
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-
natural substrates
sphingosine N-acyltransferase
palmitoyl-CoA + sphinganine = CoA + N-palmitoylsphinganine
: ceramide biosynthesis
: BS320739show the reaction diagram
: RXN-20367show the reaction diagram
-
-
-
-
natural substrates
sphingoid base N-palmitoyltransferase
palmitoyl-CoA + sphinganine = CoA + N-palmitoylsphinganine
: ceramide biosynthesis
: BS320739show the reaction diagram
: RXN-20367show the reaction diagram
-
-
-
-
natural substrates
very-long-chain ceramide synthase
palmitoyl-CoA + sphinganine = CoA + N-palmitoylsphinganine
: ceramide biosynthesis
: BS320739show the reaction diagram
: RXN-20367show the reaction diagram
-
-
-
-
natural substrates
ultra-long-chain ceramide synthase
palmitoyl-CoA + sphinganine = CoA + N-palmitoylsphinganine
: ceramide biosynthesis
: BS320739show the reaction diagram
: RXN-20367show the reaction diagram
-
-
-
-
natural substrates
sphingoid base N-stearoyltransferase
palmitoyl-CoA + sphinganine = CoA + N-palmitoylsphinganine
: ceramide biosynthesis
: BS320739show the reaction diagram
: RXN-20367show the reaction diagram
-
-
-
-
natural substrates