Print
dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose transaminase
Pathways
dTDPLrhamnose biosynthesis (BRENDA)
:= BRENDA, 
:= KEGG, 
:= MetaCyc, 
:= SABIO-RK
:= amino acid sequences 
:= show the reaction diagram
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check
Missing Substrate
Missing Product
Commentary
Remark
dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose + 2-oxoglutarate = dTDP-3-dehydro-4,6-deoxy-alpha-D-glucose + L-glutamate
; "show the reaction diagram")
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natural substrates
dTDP-4-amino-4,6-dideoxy-D-glucose ammonia-lyase
dTDP-4-amino-4,6-dideoxy-alpha-D-glucopyranose + S-adenosyl-L-methionine + reduced acceptor = dTDP-3-dehydro-4,6-dideoxy-alpha-D-glucopyranose + NH3 + L-methionine + 5'-deoxyadenosine + acceptor
; "show the reaction diagram")
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: radical SAM: The enzyme is involved in biosynthesis of TDP-D-desosamine. It contains an [4Fe-4S] cluster [19746907]. This enzyme is a member of the 'AdoMet radical' (radical SAM) family. The reaction starts by using an electron from the reduced form of the enzyme's [4Fe-4S] cluster to split S-adenosyl-L-methionine into methionine and the radical 5-deoxyadenosin-5'-yl.natural substrates, generic
dTDP-4-amino-4,6-dideoxy-D-glucose transaminase
dTDP-4-amino-4,6-dideoxy-alpha-D-glucose + 2-oxoglutarate = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + L-glutamate
; "show the reaction diagram")
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natural substrates
dTDP-4-amino-4,6-dideoxy-alpha-D-glucopyranose transaminase
dTDP-4-amino-4,6-dideoxy-alpha-D-glucose + 2-oxoglutarate = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + L-glutamate
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natural substrates
dTDP-fucopyranose mutase
dTDP-alpha-D-fucopyranose = dTDP-alpha-D-fucofuranose
; "show the reaction diagram")
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natural substrates
dTDP-4-dehydro-6-deoxyglucose reductase
dTDP-alpha-D-fucopyranose + NADP+ = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + NADPH + H+
; "show the reaction diagram")
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natural substrates
dTDP-4-dehydro-6-deoxyglucose reductase [NAD(P)H]
dTDP-alpha-D-fucopyranose + NADP+ = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + NADPH + H+
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natural substrates
dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase
dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose + NADP+ = dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose + NADPH + H+
; "show the reaction diagram")
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natural substrates
dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose 2,3-dehydratase
dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose = dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose + H2O
; "show the reaction diagram")
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natural substrates
dTDP-4-dehydro-6-deoxy-alpha-D-gulose 4-ketoreductase
dTDP-6-deoxy-alpha-D-allose + NADP+ = dTDP-4-dehydro-6-deoxy-alpha-D-gulose + NADPH + H+
; "show the reaction diagram")
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natural substrates
dTDP-4-dehydro-6-deoxy-D-glucose 3-epimerase
dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-gulose
; "show the reaction diagram")
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natural substrates
dTDP-glucose 4,6-dehydratase
dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O
: Streptomycin biosynthesis,Polyketide sugar unit biosynthesis,
Acarbose and validamycin biosynthesis,
O-Antigen nucleotide sugar biosynthesis,
Biosynthesis of vancomycin group antibiotics,
Metabolic pathways,
Biosynthesis of secondary metabolites
: dTDP-beta-L-digitoxose biosynthesis,dTDP-4-O-demethyl-beta-L-noviose biosynthesis,
dTDP-alpha-D-olivose, dTDP-alpha-D-oliose and dTDP-alpha-D-mycarose biosynthesis,
dTDP-L-daunosamine biosynthesis,
dTDP-6-deoxy-alpha-D-allose biosynthesis,
dTDP-D-desosamine biosynthesis,
dTDP-alpha-D-mycaminose biosynthesis,
dTDP-beta-L-mycarose biosynthesis,
dTDP-beta-L-olivose biosynthesis,
dTDP-alpha-D-ravidosamine and dTDP-4-acetyl-alpha-D-ravidosamine biosynthesis,
dTDP-alpha-D-forosamine biosynthesis,
dTDP-beta-L-megosamine biosynthesis,
dTDP-beta-L-4-epi-vancosamine biosynthesis,
dTDP-N-acetylthomosamine biosynthesis,
dTDP-beta-L-rhamnose biosynthesis,
dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose biosynthesis,
dTDP-N-acetylviosamine biosynthesis,
dTDP-beta-D-fucofuranose biosynthesis,
dTDP-3-acetamido-alpha-D-fucose biosynthesis
; "show the reaction diagram")
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natural substrates
UDP-glucose 4,6-dehydratase
dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O
: Streptomycin biosynthesis,Polyketide sugar unit biosynthesis,
Acarbose and validamycin biosynthesis,
O-Antigen nucleotide sugar biosynthesis,
Biosynthesis of vancomycin group antibiotics,
Metabolic pathways,
Biosynthesis of secondary metabolites
: dTDP-beta-L-digitoxose biosynthesis,dTDP-4-O-demethyl-beta-L-noviose biosynthesis,
dTDP-alpha-D-olivose, dTDP-alpha-D-oliose and dTDP-alpha-D-mycarose biosynthesis,
dTDP-L-daunosamine biosynthesis,
dTDP-6-deoxy-alpha-D-allose biosynthesis,
dTDP-D-desosamine biosynthesis,
dTDP-alpha-D-mycaminose biosynthesis,
dTDP-beta-L-mycarose biosynthesis,
dTDP-beta-L-olivose biosynthesis,
dTDP-alpha-D-ravidosamine and dTDP-4-acetyl-alpha-D-ravidosamine biosynthesis,
dTDP-alpha-D-forosamine biosynthesis,
dTDP-beta-L-megosamine biosynthesis,
dTDP-beta-L-4-epi-vancosamine biosynthesis,
dTDP-N-acetylthomosamine biosynthesis,
dTDP-beta-L-rhamnose biosynthesis,
dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose biosynthesis,
dTDP-N-acetylviosamine biosynthesis,
dTDP-beta-D-fucofuranose biosynthesis,
dTDP-3-acetamido-alpha-D-fucose biosynthesis
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natural substrates
glucose-1-phosphate thymidylyltransferase
dTTP + alpha-D-glucose 1-phosphate = diphosphate + dTDP-alpha-D-glucose
: Streptomycin biosynthesis,Polyketide sugar unit biosynthesis,
Acarbose and validamycin biosynthesis,
O-Antigen nucleotide sugar biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites
: dTDP-beta-L-digitoxose biosynthesis,dTDP-4-O-demethyl-beta-L-noviose biosynthesis,
dTDP-alpha-D-olivose, dTDP-alpha-D-oliose and dTDP-alpha-D-mycarose biosynthesis,
dTDP-L-daunosamine biosynthesis,
dTDP-6-deoxy-alpha-D-allose biosynthesis,
dTDP-D-desosamine biosynthesis,
dTDP-alpha-D-mycaminose biosynthesis,
dTDP-beta-L-mycarose biosynthesis,
dTDP-beta-L-olivose biosynthesis,
dTDP-alpha-D-ravidosamine and dTDP-4-acetyl-alpha-D-ravidosamine biosynthesis,
dTDP-alpha-D-forosamine biosynthesis,
dTDP-beta-L-megosamine biosynthesis,
dTDP-beta-L-4-epi-vancosamine biosynthesis,
dTDP-N-acetylthomosamine biosynthesis,
dTDP-beta-L-rhamnose biosynthesis,
dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose biosynthesis,
dTDP-N-acetylviosamine biosynthesis,
dTDP-beta-D-fucofuranose biosynthesis,
dTDP-3-acetamido-alpha-D-fucose biosynthesis
; "show the reaction diagram")
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natural substrates
UTP-monosaccharide-1-phosphate uridylyltransferase
dTTP + alpha-D-glucose 1-phosphate = diphosphate + dTDP-alpha-D-glucose
: Streptomycin biosynthesis,Polyketide sugar unit biosynthesis,
Acarbose and validamycin biosynthesis,
O-Antigen nucleotide sugar biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites
: dTDP-beta-L-digitoxose biosynthesis,dTDP-4-O-demethyl-beta-L-noviose biosynthesis,
dTDP-alpha-D-olivose, dTDP-alpha-D-oliose and dTDP-alpha-D-mycarose biosynthesis,
dTDP-L-daunosamine biosynthesis,
dTDP-6-deoxy-alpha-D-allose biosynthesis,
dTDP-D-desosamine biosynthesis,
dTDP-alpha-D-mycaminose biosynthesis,
dTDP-beta-L-mycarose biosynthesis,
dTDP-beta-L-olivose biosynthesis,
dTDP-alpha-D-ravidosamine and dTDP-4-acetyl-alpha-D-ravidosamine biosynthesis,
dTDP-alpha-D-forosamine biosynthesis,
dTDP-beta-L-megosamine biosynthesis,
dTDP-beta-L-4-epi-vancosamine biosynthesis,
dTDP-N-acetylthomosamine biosynthesis,
dTDP-beta-L-rhamnose biosynthesis,
dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose biosynthesis,
dTDP-N-acetylviosamine biosynthesis,
dTDP-beta-D-fucofuranose biosynthesis,
dTDP-3-acetamido-alpha-D-fucose biosynthesis
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natural substrates
UTP-glucose-1-phosphate uridylyltransferase
dTTP + alpha-D-glucose 1-phosphate = diphosphate + dTDP-alpha-D-glucose
: Streptomycin biosynthesis,Polyketide sugar unit biosynthesis,
Acarbose and validamycin biosynthesis,
O-Antigen nucleotide sugar biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites
: dTDP-beta-L-digitoxose biosynthesis,dTDP-4-O-demethyl-beta-L-noviose biosynthesis,
dTDP-alpha-D-olivose, dTDP-alpha-D-oliose and dTDP-alpha-D-mycarose biosynthesis,
dTDP-L-daunosamine biosynthesis,
dTDP-6-deoxy-alpha-D-allose biosynthesis,
dTDP-D-desosamine biosynthesis,
dTDP-alpha-D-mycaminose biosynthesis,
dTDP-beta-L-mycarose biosynthesis,
dTDP-beta-L-olivose biosynthesis,
dTDP-alpha-D-ravidosamine and dTDP-4-acetyl-alpha-D-ravidosamine biosynthesis,
dTDP-alpha-D-forosamine biosynthesis,
dTDP-beta-L-megosamine biosynthesis,
dTDP-beta-L-4-epi-vancosamine biosynthesis,
dTDP-N-acetylthomosamine biosynthesis,
dTDP-beta-L-rhamnose biosynthesis,
dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose biosynthesis,
dTDP-N-acetylviosamine biosynthesis,
dTDP-beta-D-fucofuranose biosynthesis,
dTDP-3-acetamido-alpha-D-fucose biosynthesis
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natural substrates
dTDP-4-dehydrorhamnose 3,5-epimerase
dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-4-dehydro-beta-L-rhamnose
; "show the reaction diagram")
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natural substrates
dTDP-4-dehydrorhamnose reductase
dTDP-beta-L-rhamnose + NADP+ = dTDP-4-dehydro-beta-L-rhamnose + NADPH + H+
; "show the reaction diagram")
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natural substrates