Pathways

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BRENDA KEGG MetaCyc

isoleucine metabolism (BRENDA)

:= BRENDA, := KEGG, := MetaCyc, := SABIO-RK
:= amino acid sequences := show the reaction diagram
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check
Missing Substrate
Missing Product
Commentary
Remark
oxaloacetate decarboxylase
3-methyloxaloacetate = 2-oxobutanoate + CO2
R00995 show the reaction diagram
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natural substrates
3-methyloxaloacetate = 2-oxobutanoate + CO2
R00995 show the reaction diagram
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natural substrates
2-isopropylmalate synthase
acetyl-CoA + pyruvate + H2O = CoA + (2R)-2-hydroxy-2-methylbutanedioate
BR48833 show the reaction diagram
R07399 show the reaction diagram
9043
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natural substrates
(R)-citramalate synthase
acetyl-CoA + pyruvate + H2O = CoA + (2R)-2-hydroxy-2-methylbutanedioate
BR48833 show the reaction diagram
R07399 show the reaction diagram
9043
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natural substrates
acetolactate synthase
pyruvate + 2-oxobutyrate = 2-aceto-2-hydroxybutyrate + CO2
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natural substrates
ketol-acid reductoisomerase (NADP+)
2-aceto-2-hydroxybutyrate + NADPH = 2,3-dihydroxy-3-methylvalerate + NADP+
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natural substrates
dihydroxy-acid dehydratase
2,3-dihydroxy-3-methylpentanoate = 3-methyl-2-oxopentanoate + H2O
BS18755 show the reaction diagram
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pyruvate synthase
2-oxobutyrate + CoA + oxidized ferredoxin = propanoyl-CoA + CO2 + reduced ferredoxin
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natural substrates, generic, protein
2-oxoacid oxidoreductase (ferredoxin)
2-oxobutyrate + CoA + oxidized ferredoxin = propanoyl-CoA + CO2 + reduced ferredoxin
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natural substrates, generic, protein
3-methyl-2-oxobutanoate dehydrogenase (ferredoxin)
2-oxobutyrate + CoA + oxidized ferredoxin = propanoyl-CoA + CO2 + reduced ferredoxin
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natural substrates, generic, protein
acetate-CoA ligase
ATP + propanoate + CoA = AMP + diphosphate + propanoyl-CoA
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: two-step reaction (see R01354+R00926)
natural substrates
propionate-CoA ligase
ATP + propanoate + CoA = AMP + diphosphate + propanoyl-CoA
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: two-step reaction (see R01354+R00926)
natural substrates
medium-chain acyl-CoA ligase
ATP + propanoate + CoA = AMP + diphosphate + propanoyl-CoA
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: two-step reaction (see R01354+R00926)
natural substrates
phenylacetate-CoA ligase
ATP + propanoate + CoA = AMP + diphosphate + propanoyl-CoA
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: two-step reaction (see R01354+R00926)
natural substrates
3-hydroxypropionyl-CoA synthase
ATP + propanoate + CoA = AMP + diphosphate + propanoyl-CoA
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: two-step reaction (see R01354+R00926)
natural substrates
3-(methylthio)propionyl-CoA ligase
ATP + propanoate + CoA = AMP + diphosphate + propanoyl-CoA
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: two-step reaction (see R01354+R00926)
natural substrates
isoleucine-tRNA ligase
ATP + L-isoleucine + tRNAIle = AMP + diphosphate + L-isoleucyl-tRNAIle
BR56 show the reaction diagram
R03656 show the reaction diagram
413
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natural substrates
valine-tRNA ligase
ATP + L-isoleucine + tRNAIle = AMP + diphosphate + L-isoleucyl-tRNAIle
BR56 show the reaction diagram
R03656 show the reaction diagram
413
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natural substrates