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BRENDA KEGG MetaCyc

lipoate biosynthesis (BRENDA)

:= BRENDA, := KEGG, := MetaCyc, := SABIO-RK
:= amino acid sequences := show the reaction diagram
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check
Missing Substrate
Missing Product
Commentary
Remark
long-chain-fatty-acid-[acyl-carrier-protein] ligase
ATP + octanoic acid + [acyl-carrier protein] = AMP + diphosphate + octanoyl-[acyl-carrier protein]
BS215 show the reaction diagram
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protein
lipoyl(octanoyl) transferase
octanoyl-[acyl-carrier protein] + protein = protein 6-N-(octanoyl)lysine + acyl carrier protein
BR48667 show the reaction diagram
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natural substrates, protein
lipoyl synthase
protein N6-(octanoyl)lysine + sulfur + S-adenosyl-L-methionine = protein N6-(lipoyl)lysine + 2 L-methionine + 2 5'-deoxyadenosyl radicals
generic compounds
H22C15S2O5N6
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generic, protein
ATP + (R)-lipoate = lipoyl-AMP + diphosphate
BR48678 show the reaction diagram
R07770 show the reaction diagram
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natural substrates
lipoate-protein ligase
ATP + (R)-lipoate = lipoyl-AMP + diphosphate
BR48678 show the reaction diagram
R07770 show the reaction diagram
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natural substrates