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Pathways

metabolism of disaccharids (BRENDA)

:= BRENDA,

:= KEGG,

:= MetaCyc,

:= SABIO-RK

:= amino acid sequences

:= show the reaction diagram

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EC Number

Reaction

Pathways

Reaction IDs

Stoichiometry Check

Missing Substrate

Missing Product

Commentary

Remark

2.7.1.1

hexokinase

ATP + D-fructose = ADP + D-fructose 6-phosphate

: metabolism of disaccharids

: Starch and sucrose metabolism,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Fructose and mannose metabolism,
Amino sugar and nucleotide sugar metabolism

: sucrose degradation I (sucrose phosphotransferase),
sucrose degradation VII (sucrose 3-dehydrogenase),
sucrose degradation III (sucrose invertase),
heterolactic fermentation,
sucrose degradation II (sucrose synthase),
sucrose degradation IV (sucrose phosphorylase),
mannitol cycle,
D-sorbitol degradation I

: BR47777

: R00760

, R00867

, R03920

: FRUCTOKINASE-RXN

: 1116, 8091

natural substrates

2.7.1.15

ribokinase

ATP + D-fructose = ADP + D-fructose 6-phosphate

: metabolism of disaccharids

: Starch and sucrose metabolism,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Fructose and mannose metabolism,
Amino sugar and nucleotide sugar metabolism

: BR47777

: R00760

, R00867

, R03920

: FRUCTOKINASE-RXN

: 1116, 8091

natural substrates

2.7.1.2

glucokinase

ATP + D-fructose = ADP + D-fructose 6-phosphate

: metabolism of disaccharids

: Starch and sucrose metabolism,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Fructose and mannose metabolism,
Amino sugar and nucleotide sugar metabolism

: BR47777

: R00760

, R00867

, R03920

: FRUCTOKINASE-RXN

: 1116, 8091

natural substrates

2.7.1.4

fructokinase

ATP + D-fructose = ADP + D-fructose 6-phosphate

: metabolism of disaccharids

: Starch and sucrose metabolism,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Fructose and mannose metabolism,
Amino sugar and nucleotide sugar metabolism

: BR47777

: R00760

, R00867

, R03920

: FRUCTOKINASE-RXN

: 1116, 8091

natural substrates

3.2.1.122

maltose-6'-phosphate glucosidase

alpha,alpha-trehalose 6-phosphate + H2O = D-glucose + D-glucose 6-phosphate

: metabolism of disaccharids

: Starch and sucrose metabolism,
Metabolic pathways

: trehalose degradation I (low osmolarity)

: BR16035

: R00837

, R06113

: TRE6PHYDRO-RXN

: 1178, 9171

natural substrates

3.2.1.93

alpha,alpha-phosphotrehalase

alpha,alpha-trehalose 6-phosphate + H2O = D-glucose + D-glucose 6-phosphate

: metabolism of disaccharids

: Starch and sucrose metabolism,
Metabolic pathways

: trehalose degradation I (low osmolarity)

: BR16035

: R00837

, R06113

: TRE6PHYDRO-RXN

: 1178, 9171

natural substrates

2.4.1.329

sucrose 6F-phosphate phosphorylase

sucrose + phosphate = D-fructose + alpha-D-glucose 1-phosphate

: metabolism of disaccharids

: Starch and sucrose metabolism,
Metabolic pathways

: sucrose degradation IV (sucrose phosphorylase)

: BR47498

, BS375309

, BS407397

: R00803

, R06034

: SUCROSE-PHOSPHORYLASE-RXN

: 1148

natural substrates

2.4.1.7

sucrose phosphorylase

sucrose + phosphate = D-fructose + alpha-D-glucose 1-phosphate

: metabolism of disaccharids

: Starch and sucrose metabolism,
Metabolic pathways

: sucrose degradation IV (sucrose phosphorylase)

: BR47498

, BS375309

, BS407397

: R00803

, R06034

: SUCROSE-PHOSPHORYLASE-RXN

: 1148

natural substrates

5.3.1.26

galactose-6-phosphate isomerase

D-Galactose 6-phosphate = D-tagatose 6-phosphate

: metabolism of disaccharids

: Galactose metabolism,
Metabolic pathways

: lactose and galactose degradation I

: BR233

: R03240

: LACTOSE-6-PHOSPHATE-ISOMERASE-RXN

: 559

natural substrates

2.7.1.11

6-phosphofructokinase

ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate

: metabolism of disaccharids,
degradation of sugar alcohols

: Galactose metabolism,
Metabolic pathways

: galactitol degradation,
lactose and galactose degradation I,
N-acetyl-D-galactosamine degradation,
D-galactosamine and N-acetyl-D-galactosamine degradation

: BR47754

: R03236

: TAGAKIN-RXN

: 3059

natural substrates

2.7.1.144

tagatose-6-phosphate kinase

ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate

: metabolism of disaccharids,
degradation of sugar alcohols

: Galactose metabolism,
Metabolic pathways

: galactitol degradation,
lactose and galactose degradation I,
N-acetyl-D-galactosamine degradation,
D-galactosamine and N-acetyl-D-galactosamine degradation

: BR47754

: R03236

: TAGAKIN-RXN

: 3059

natural substrates

2.7.1.56

1-phosphofructokinase

ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate

: metabolism of disaccharids,
degradation of sugar alcohols

: Galactose metabolism,
Metabolic pathways

: galactitol degradation,
lactose and galactose degradation I,
N-acetyl-D-galactosamine degradation,
D-galactosamine and N-acetyl-D-galactosamine degradation

: BR47754

: R03236

: TAGAKIN-RXN

: 3059

natural substrates

4.1.2.13

fructose-bisphosphate aldolase

D-tagatose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate

: metabolism of disaccharids,
degradation of sugar alcohols

: Galactose metabolism,
Metabolic pathways

: galactitol degradation,
lactose and galactose degradation I,
N-acetyl-D-galactosamine degradation,
D-galactosamine and N-acetyl-D-galactosamine degradation

: BR372

: R01069

: TAGAALDOL-RXN

: 1339

natural substrates

4.1.2.40

tagatose-bisphosphate aldolase

D-tagatose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate

: metabolism of disaccharids,
degradation of sugar alcohols

: Galactose metabolism,
Metabolic pathways

: galactitol degradation,
lactose and galactose degradation I,
N-acetyl-D-galactosamine degradation,
D-galactosamine and N-acetyl-D-galactosamine degradation

: BR372

: R01069

: TAGAALDOL-RXN

: 1339

natural substrates

3.1.3.1

alkaline phosphatase

alpha,alpha-trehalose 6-phosphate + H2O = alpha,alpha-trehalose + phosphate

: metabolism of disaccharids

: Starch and sucrose metabolism,
Metabolic pathways,
Biosynthesis of secondary metabolites

: trehalose biosynthesis III,
glycogen biosynthesis III (from alpha-maltose 1-phosphate),
trehalose biosynthesis I,
trehalose biosynthesis II

: BR15936

: R02778

, R06228

: TREHALOSEPHOSPHA-RXN

: 2655

natural substrates

3.1.3.101

validoxylamine A 7'-phosphate phosphatase

alpha,alpha-trehalose 6-phosphate + H2O = alpha,alpha-trehalose + phosphate

: metabolism of disaccharids

: Starch and sucrose metabolism,
Metabolic pathways,
Biosynthesis of secondary metabolites

: trehalose biosynthesis III,
glycogen biosynthesis III (from alpha-maltose 1-phosphate),
trehalose biosynthesis I,
trehalose biosynthesis II

: BR15936

: R02778

, R06228

: TREHALOSEPHOSPHA-RXN

: 2655

natural substrates

3.1.3.12

trehalose-phosphatase

alpha,alpha-trehalose 6-phosphate + H2O = alpha,alpha-trehalose + phosphate

: metabolism of disaccharids

: Starch and sucrose metabolism,
Metabolic pathways,
Biosynthesis of secondary metabolites

: trehalose biosynthesis III,
glycogen biosynthesis III (from alpha-maltose 1-phosphate),
trehalose biosynthesis I,
trehalose biosynthesis II

: BR15936

: R02778

, R06228

: TREHALOSEPHOSPHA-RXN

: 2655

natural substrates

2.4.1.15

alpha,alpha-trehalose-phosphate synthase (UDP-forming)

UDP-alpha-D-glucose + D-glucose 6-phosphate = UDP + alpha,alpha-trehalose 6-phosphate

: metabolism of disaccharids

: trehalose biosynthesis I

: BR44159

: R00836

, R06043

: TREHALOSE6PSYN-RXN

: 1177

natural substrates

3.2.1.122

maltose-6'-phosphate glucosidase

sucrose 6-phosphate + H2O = D-glucose 6-phosphate + D-fructose

: metabolism of disaccharids

: Starch and sucrose metabolism

: BS361170

: R03921

: 10703

natural substrates

3.2.1.26

beta-fructofuranosidase

sucrose 6-phosphate + H2O = D-glucose 6-phosphate + D-fructose

: metabolism of disaccharids

: Starch and sucrose metabolism

: BS361170

: R03921

: 10703

natural substrates

3.2.1.B3

sucrose 6-phosphate hydrolase

sucrose 6-phosphate + H2O = D-glucose 6-phosphate + D-fructose

: metabolism of disaccharids

: Starch and sucrose metabolism

: BS361170

: R03921

: 10703

natural substrates

3.2.1.10

oligo-1,6-glucosidase

alpha,alpha-trehalose + H2O = beta-D-glucose + alpha-D-glucose

: metabolism of disaccharids

: Starch and sucrose metabolism,
Metabolic pathways,
Biosynthesis of secondary metabolites

: trehalose degradation VI (periplasmic),
trehalose degradation II (cytosolic)

: BR15991

, BS259712

, BS370856

, BS372300

: R00010

, R06103

: TREHALA-RXN

: 11797, 6476

natural substrates

3.2.1.20

alpha-glucosidase

alpha,alpha-trehalose + H2O = beta-D-glucose + alpha-D-glucose

: metabolism of disaccharids

: Starch and sucrose metabolism,
Metabolic pathways,
Biosynthesis of secondary metabolites

: trehalose degradation VI (periplasmic),
trehalose degradation II (cytosolic)

: BR15991

, BS259712

, BS370856

, BS372300

: R00010

, R06103

: TREHALA-RXN

: 11797, 6476

natural substrates

3.2.1.28

alpha,alpha-trehalase

alpha,alpha-trehalose + H2O = beta-D-glucose + alpha-D-glucose

: metabolism of disaccharids

: Starch and sucrose metabolism,
Metabolic pathways,
Biosynthesis of secondary metabolites

: trehalose degradation VI (periplasmic),
trehalose degradation II (cytosolic)

: BR15991

, BS259712

, BS370856

, BS372300

: R00010

, R06103

: TREHALA-RXN

: 11797, 6476

natural substrates

3.2.1.3

glucan 1,4-alpha-glucosidase

alpha,alpha-trehalose + H2O = beta-D-glucose + alpha-D-glucose

: metabolism of disaccharids

: Starch and sucrose metabolism,
Metabolic pathways,
Biosynthesis of secondary metabolites

: trehalose degradation VI (periplasmic),
trehalose degradation II (cytosolic)

: BR15991

, BS259712

, BS370856

, BS372300

: R00010

, R06103

: TREHALA-RXN

: 11797, 6476

natural substrates

3.2.1.108

lactase

lactose + H2O = D-galactose + D-glucose

: metabolism of disaccharids

: Galactose metabolism,
Metabolic pathways

: lactose degradation III

: BR29501

: R01100

, R01678

, R06098

, R06114

: BETAGALACTOSID-RXN

: 46, 9724

natural substrates

3.2.1.21

beta-glucosidase

lactose + H2O = D-galactose + D-glucose

: metabolism of disaccharids

: Galactose metabolism,
Metabolic pathways

: lactose degradation III

: BR29501

: R01100

, R01678

, R06098

, R06114

: BETAGALACTOSID-RXN

: 46, 9724

natural substrates

3.2.1.22

alpha-galactosidase

lactose + H2O = D-galactose + D-glucose

: metabolism of disaccharids

: Galactose metabolism,
Metabolic pathways

: lactose degradation III

: BR29501

: R01100

, R01678

, R06098

, R06114

: BETAGALACTOSID-RXN

: 46, 9724

natural substrates

3.2.1.23

beta-galactosidase

lactose + H2O = D-galactose + D-glucose

: metabolism of disaccharids

: Galactose metabolism,
Metabolic pathways

: lactose degradation III

: BR29501

: R01100

, R01678

, R06098

, R06114

: BETAGALACTOSID-RXN

: 46, 9724

natural substrates

3.2.1.38

beta-D-fucosidase

lactose + H2O = D-galactose + D-glucose

: metabolism of disaccharids

: Galactose metabolism,
Metabolic pathways

: lactose degradation III

: BR29501

: R01100

, R01678

, R06098

, R06114

: BETAGALACTOSID-RXN

: 46, 9724

natural substrates

3.2.1.62

glycosylceramidase

lactose + H2O = D-galactose + D-glucose

: metabolism of disaccharids

: Galactose metabolism,
Metabolic pathways

: lactose degradation III

: BR29501

: R01100

, R01678

, R06098

, R06114

: BETAGALACTOSID-RXN

: 46, 9724

natural substrates

3.2.1.85

6-phospho-beta-galactosidase

lactose + H2O = D-galactose + D-glucose

: metabolism of disaccharids

: Galactose metabolism,
Metabolic pathways

: lactose degradation III

: BR29501

: R01100

, R01678

, R06098

, R06114

: BETAGALACTOSID-RXN

: 46, 9724

natural substrates

3.2.1.B26

Sulfolobus solfataricus beta-glycosidase

lactose + H2O = D-galactose + D-glucose

: metabolism of disaccharids

: Galactose metabolism,
Metabolic pathways

: lactose degradation III

: BR29501

: R01100

, R01678

, R06098

, R06114

: BETAGALACTOSID-RXN

: 46, 9724

natural substrates

3.2.1.B28

Pyrococcus furiosus beta-glycosidase

lactose + H2O = D-galactose + D-glucose

: metabolism of disaccharids

: Galactose metabolism,
Metabolic pathways

: lactose degradation III

: BR29501

: R01100

, R01678

, R06098

, R06114

: BETAGALACTOSID-RXN

: 46, 9724

natural substrates

3.2.1.B33

Sulfolobus shibatae beta-glycosidase

lactose + H2O = D-galactose + D-glucose

: metabolism of disaccharids

: Galactose metabolism,
Metabolic pathways

: lactose degradation III

: BR29501

: R01100

, R01678

, R06098

, R06114

: BETAGALACTOSID-RXN

: 46, 9724

natural substrates

3.2.1.B34

Sulfolobus acidocaldarius beta-glycosidase

lactose + H2O = D-galactose + D-glucose

: metabolism of disaccharids

: Galactose metabolism,
Metabolic pathways

: lactose degradation III

: BR29501

: R01100

, R01678

, R06098

, R06114

: BETAGALACTOSID-RXN

: 46, 9724

natural substrates

3.7.1.4

phloretin hydrolase

lactose + H2O = D-galactose + D-glucose

: metabolism of disaccharids

: Galactose metabolism,
Metabolic pathways

: lactose degradation III

: BR29501

: R01100

, R01678

, R06098

, R06114

: BETAGALACTOSID-RXN

: 46, 9724

natural substrates

5.4.99.16

maltose alpha-D-glucosyltransferase

maltose = alpha,alpha-trehalose

: metabolism of disaccharids

: Starch and sucrose metabolism,
Metabolic pathways

: glycogen biosynthesis III (from alpha-maltose 1-phosphate),
trehalose biosynthesis IV

: BR248

: R01557

, R06218

: 5.4.99.16-RXN

natural substrates