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BRENDA KEGG MetaCyc

mevalonate metabolism (BRENDA)

:= BRENDA, := KEGG, := MetaCyc, := SABIO-RK
:= amino acid sequences := show the reaction diagram
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check
Missing Substrate
Missing Product
Commentary
Remark
mevalonate-3-phosphate 5-kinase
ATP + (R)-3-phosphomevalonate = ADP + (R)-3,5-bisphosphomevalonate
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natural substrates
mevalonate 3-kinase
ATP + (R)-mevalonate = ADP + (R)-3-phosphomevalonate
BR51126 show the reaction diagram
R10779 show the reaction diagram
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natural substrates
hydroxymethylglutaryl-CoA reductase (NADPH)
(R)-mevalonate + CoA + 2 NAD+ = 3-hydroxy-3-methylglutaryl-CoA + 2 NADH + 2 H+
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natural substrates
hydroxymethylglutaryl-CoA reductase
(R)-mevalonate + CoA + 2 NAD+ = 3-hydroxy-3-methylglutaryl-CoA + 2 NADH + 2 H+
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natural substrates
hydroxymethylglutaryl-CoA reductase [NAD(P)H]
(R)-mevalonate + CoA + 2 NAD+ = 3-hydroxy-3-methylglutaryl-CoA + 2 NADH + 2 H+
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natural substrates
acetyl-CoA C-acetyltransferase
2 acetyl-CoA = CoA + acetoacetyl-CoA
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natural substrates
acetyl-CoA C-myristoyltransferase
2 acetyl-CoA = CoA + acetoacetyl-CoA
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natural substrates
acetyl-CoA C-acyltransferase
2 acetyl-CoA = CoA + acetoacetyl-CoA
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natural substrates
[acyl-carrier-protein] S-acetyltransferase
2 acetyl-CoA = CoA + acetoacetyl-CoA
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natural substrates
hydroxymethylglutaryl-CoA reductase (NADPH)
2 acetyl-CoA = CoA + acetoacetyl-CoA
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natural substrates
isopentenyl phosphate kinase
ATP + isopentenyl phosphate = ADP + isopentenyl diphosphate
BR50003 show the reaction diagram
R10093 show the reaction diagram
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natural substrates
diphosphomevalonate decarboxylase
ATP + (R)-5-diphosphomevalonate = ADP + phosphate + isopentenyl diphosphate + CO2
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: possibly intermediate ((R)-5-diphospho-3-phosphomevalonate)
natural substrates
bisphosphomevalonate decarboxylase
(R)-3,5-bisphosphomevalonate = isopentenyl phosphate + CO2 + phosphate
BR52424 show the reaction diagram
R10781 show the reaction diagram
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: This hypothetical reaction is catalyzed by an as yet unidentified mevalonate-3,5-bisphosphate decarboxylase |CITS: [24914732][24755225]|.
natural substrates
adenylate dimethylallyltransferase (ADP/ATP-dependent)
dimethylallyl diphosphate + ADP = diphosphate + N6-(dimethylallyl)adenosine 5'-diphosphate
BR50802 show the reaction diagram
R08052 show the reaction diagram
7651
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natural substrates
adenylate dimethylallyltransferase
dimethylallyl diphosphate + ADP = diphosphate + N6-(dimethylallyl)adenosine 5'-diphosphate
BR50802 show the reaction diagram
R08052 show the reaction diagram
7651
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natural substrates