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BRENDA KEGG MetaCyc

peptidoglycan biosynthesis (BRENDA)

:= BRENDA, := KEGG, := MetaCyc, := SABIO-RK
:= amino acid sequences := show the reaction diagram
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check
Missing Substrate
Missing Product
Commentary
Remark
lipid II:glycine glycyltransferase
N-acetylmuramoyl-L-alanyl-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine-diphospho-ditrans,octacis-undecaprenyl-N-acetyl-D-glucosamine + glycyl-tRNAGly = N-acetylmuramoyl-L-alanyl-D-isoglutaminyl-L-lysyl-(N6-glycyl)-D-alanyl-D-alanine-diphospho-ditrans,octacis-undecaprenyl-N-acetyl-D-glucosamine + tRNAGly
BR49239 show the reaction diagram
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natural substrates, nucleotide
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase
UDP-N-acetyl-alpha-D-glucosamine + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = UDP + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol
BR44201 show the reaction diagram
R05662 show the reaction diagram, R06173 show the reaction diagram
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natural substrates
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase
ATP + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate + L-lysine = ADP + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysine
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natural substrates
D-stereospecific aminopeptidase
D-Ala-D-Ala + H2O = 2 D-Ala
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natural substrates
non-stereospecific dipeptidase
D-Ala-D-Ala + H2O = 2 D-Ala
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natural substrates
membrane dipeptidase
D-Ala-D-Ala + H2O = 2 D-Ala
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natural substrates
D-Ala-D-Ala dipeptidase
D-Ala-D-Ala + H2O = 2 D-Ala
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natural substrates
serine-type D-Ala-D-Ala carboxypeptidase
D-Ala-D-Ala + H2O = 2 D-Ala
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natural substrates
UDP-N-acetylmuramoyl-L-alanine-D-glutamate ligase
ATP + UDP-N-acetyl-alpha-D-muramoyl-L-alanine + D-glutamate = ADP + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate
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natural substrates
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-2,6-diaminopimelate ligase
ATP + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate + meso-2,6-diaminoheptanedioate = ADP + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate
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natural substrates
phospho-N-acetylmuramoyl-pentapeptide-transferase
UDP-N-acetylmuramoyl-pentapeptide + undecaprenyl phosphate = UMP + N-acetylmuramoyl-pentapeptide-diphosphoundecaprenol
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natural substrates
undecaprenyl-diphosphate phosphatase
ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate
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natural substrates
UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
ATP + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysine + D-alanyl-D-alanine = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine
BR102 show the reaction diagram
R04573 show the reaction diagram
4244
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natural substrates
D-Alanine-D-alanine ligase
ATP + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysine + D-alanyl-D-alanine = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine
BR102 show the reaction diagram
R04573 show the reaction diagram
4244
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natural substrates
phospho-N-acetylmuramoyl-pentapeptide-transferase
UDP-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala) + undecaprenyl phosphate = UMP + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol
BR48088 show the reaction diagram
R05629 show the reaction diagram
5227
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natural substrates