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BRENDA KEGG MetaCyc

phenylalanine metabolism (BRENDA)

:= BRENDA, := KEGG, := MetaCyc, := SABIO-RK
:= amino acid sequences := show the reaction diagram
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check
Missing Substrate
Missing Product
Commentary
Remark
3-(aryl)acrylate reductase
3-phenylpropanoate + electron-transfer flavoprotein = trans-cinnamate + reduced electron-transfer flavoprotein
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natural substrates, protein
phenyllactyl-CoA dehydratase
(R)-3-(phenyl)lactoyl-CoA = (E)-cinnamoyl-CoA + H2O
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natural substrates
phenylalanine aminomutase (L-beta-phenylalanine forming)
L-phenylalanine = L-beta-phenylalanine
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natural substrates
phenylalanine aminomutase (D-beta-phenylalanine forming)
L-phenylalanine = L-beta-phenylalanine
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natural substrates
3-methyl-2-oxobutanoate dehydrogenase (ferredoxin)
phenylpyruvate + CoA + oxidized ferredoxin = phenylacetyl-CoA + CO2 + reduced ferredoxin
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indolepyruvate ferredoxin oxidoreductase
phenylpyruvate + CoA + oxidized ferredoxin = phenylacetyl-CoA + CO2 + reduced ferredoxin
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phenylalanine-tRNA ligase
ATP + L-phenylalanine + tRNAPhe = AMP + diphosphate + L-phenylalanyl-tRNAPhe
BR51show the reaction diagram
409
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natural substrates
phenylalanine 4-monooxygenase
L-Phenylalanine + Tetrahydropteridine + Oxygen <=> L-Tyrosine + 4a-Hydroxy-5,6,7,8-tetrahydropteridine
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natural substrates
4a-hydroxytetrahydrobiopterin dehydratase
4a-hydroxy-tetrahydrobiopterin = 7,8-dihydrobiopterin + H2O
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natural substrates
branched-chain-2-oxoacid decarboxylase
phenylpyruvate = phenylacetaldehyde + CO2
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natural substrates
alcohol dehydrogenase
phenylethanol + NAD+ = phenylacetaldehyde + NADH
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natural substrates
indole-3-acetaldehyde reductase (NADH)
phenylethanol + NAD+ = phenylacetaldehyde + NADH
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natural substrates
alcohol dehydrogenase [NAD(P)+]
phenylethanol + NAD+ = phenylacetaldehyde + NADH
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natural substrates
aryl-alcohol dehydrogenase
phenylethanol + NAD+ = phenylacetaldehyde + NADH
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natural substrates
(S)-specific secondary alcohol dehydrogenase
phenylethanol + NAD+ = phenylacetaldehyde + NADH
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natural substrates
phenylalanine racemase (ATP-hydrolysing)
ATP + L-phenylalanine + H2O = AMP + diphosphate + D-phenylalanine
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: multi-step reaction (ligating L-phenylalanine and [enzyme]-thiol, epimerizing and thioester-hydrolysing)
natural substrates, multi-step reaction
3-(aryl)acryloyl-CoA:(R)-3-(aryl)lactate CoA-transferase
(E)-cinnamoyl-CoA + (R)-(phenyl)lactate = (E)-cinnamate + (R)-(phenyl)lactoyl-CoA
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natural substrates