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5-methyltetrahydrofolate:corrinoid/iron-sulfur protein Co-methyltransferase
Pathways
reductive acetyl coenzyme A pathway (BRENDA)
:= BRENDA, 
:= KEGG, 
:= MetaCyc, 
:= SABIO-RK
:= amino acid sequences 
:= show the reaction diagram
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check
Missing Substrate
Missing Product
Commentary
Remark
a [methyl-Co(III) corrinoid Fe-S protein] + tetrahydrofolate = a [Co(I) corrinoid Fe-S protein] + 5-methyltetrahydrofolate
generic compounds
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natural substrates, generic, protein
CO-methylating acetyl-CoA synthase
acetyl-CoA + a [Co(I) corrinoid Fe-S protein] = CO + CoA + a [methyl-Co(III) corrinoid Fe-S protein]
n.a.
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natural substrates, protein
methylenetetrahydrofolate reductase [NAD(P)H]
5-methyltetrahydrofolate + oxidized ferredoxin = 5,10-methylenetetrahydrofolate + reduced ferredoxin + 2 H+
; "show the reaction diagram")
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natural substrates, generic, protein
methylenetetrahydrofolate reductase (ferredoxin)
5-methyltetrahydrofolate + oxidized ferredoxin = 5,10-methylenetetrahydrofolate + reduced ferredoxin + 2 H+
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natural substrates, generic, protein
methylenetetrahydrofolate dehydrogenase (NAD+)
5,10-methylenetetrahydrofolate + NADP+ = 5,10-methenyltetrahydrofolate + NADPH + H+
: One carbon pool by folate,Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism
: reductive acetyl coenzyme A pathway I (homoacetogenic bacteria),folate transformations I,
formaldehyde oxidation VII (THF pathway),
formate assimilation into 5,10-methylenetetrahydrofolate,
folate transformations III (E. coli),
folate transformations II (plants),
purine nucleobases degradation II (anaerobic)
; "show the reaction diagram")
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natural substrates
methylenetetrahydrofolate dehydrogenase (NADP+)
5,10-methylenetetrahydrofolate + NADP+ = 5,10-methenyltetrahydrofolate + NADPH + H+
: One carbon pool by folate,Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism
: reductive acetyl coenzyme A pathway I (homoacetogenic bacteria),folate transformations I,
formaldehyde oxidation VII (THF pathway),
formate assimilation into 5,10-methylenetetrahydrofolate,
folate transformations III (E. coli),
folate transformations II (plants),
purine nucleobases degradation II (anaerobic)
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natural substrates
formate dehydrogenase (acceptor)
formate + acceptor = CO2 + reduced acceptor
; "show the reaction diagram")
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natural substrates, generic
formate dehydrogenase (NADP+)
formate + NAD+ = CO2 + NADH + H+
; "show the reaction diagram")
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natural substrates
formate dehydrogenase
formate + NAD+ = CO2 + NADH + H+
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natural substrates
methenyltetrahydrofolate cyclohydrolase
5,10-methenyltetrahydrofolate + H2O = 10-formyltetrahydrofolate
: One carbon pool by folate,Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism
: reductive acetyl coenzyme A pathway I (homoacetogenic bacteria),purine nucleobases degradation I (anaerobic),
folate transformations I,
formaldehyde oxidation VII (THF pathway),
formate assimilation into 5,10-methylenetetrahydrofolate,
folate transformations III (E. coli),
folate transformations II (plants),
tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate,
purine nucleobases degradation II (anaerobic),
L-histidine degradation III
; "show the reaction diagram")
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natural substrates
formate-tetrahydrofolate ligase
ATP + formate + tetrahydrofolate = ADP + phosphate + 10-formyltetrahydrofolate
; "show the reaction diagram")
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natural substrates
anaerobic carbon-monoxide dehydrogenase
CO + H2O + 2 oxidized ferredoxin = CO2 + 2 reduced ferredoxin + 2 H+
; "show the reaction diagram")
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natural substrates, generic, protein
formate dehydrogenase (NADP+)
formate + NADP+ = CO2 + NADPH + H+
; "show the reaction diagram")
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natural substrates
formate dehydrogenase
formate + NADP+ = CO2 + NADPH + H+
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natural substrates