formate dehydrogenase (NADP+)
Pathways
reductive acetyl coenzyme A pathway (BRENDA)
:= BRENDA, := KEGG, := MetaCyc, := SABIO-RK
:= amino acid sequences := show the reaction diagram
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check
Missing Substrate
Missing Product
Commentary
Remark
formate + NADP+ = CO2 + NADPH + H+
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natural substrates
formate dehydrogenase
formate + NADP+ = CO2 + NADPH + H+
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natural substrates
anaerobic carbon-monoxide dehydrogenase
CO + H2O + 2 oxidized ferredoxin = CO2 + 2 reduced ferredoxin + 2 H+
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natural substrates, generic, protein
formate-tetrahydrofolate ligase
ATP + formate + tetrahydrofolate = ADP + phosphate + 10-formyltetrahydrofolate
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natural substrates
methenyltetrahydrofolate cyclohydrolase
5,10-methenyltetrahydrofolate + H2O = 10-formyltetrahydrofolate
: One carbon pool by folate,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism,
Biosynthesis of cofactors
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism,
Biosynthesis of cofactors
: reductive glycine pathway of autotrophic CO2 fixation,
folate transformations I,
reductive acetyl coenzyme A pathway I (homoacetogenic bacteria),
purine nucleobases degradation I (anaerobic),
formaldehyde oxidation VII (THF pathway),
formate assimilation into 5,10-methylenetetrahydrofolate,
folate transformations III (E. coli),
folate transformations II (plants),
tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate,
purine nucleobases degradation II (anaerobic),
L-histidine degradation III
folate transformations I,
reductive acetyl coenzyme A pathway I (homoacetogenic bacteria),
purine nucleobases degradation I (anaerobic),
formaldehyde oxidation VII (THF pathway),
formate assimilation into 5,10-methylenetetrahydrofolate,
folate transformations III (E. coli),
folate transformations II (plants),
tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate,
purine nucleobases degradation II (anaerobic),
L-histidine degradation III
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natural substrates
anaerobic carbon-monoxide dehydrogenase
CO + H2O + electron acceptor = CO2 + reduced electron acceptor
: BS370135
generic compounds
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natural substrates, generic
formate dehydrogenase
formate + NAD+ = CO2 + NADH + H+
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natural substrates
formate dehydrogenase (hydrogenase)
formate + an [oxidized hydrogenase] = CO2 + a [reduced hydrogenase]
: BR49158
generic compounds
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natural substrates, generic
methylenetetrahydrofolate dehydrogenase (NAD+)
5,10-methylenetetrahydrofolate + NADP+ = 5,10-methenyltetrahydrofolate + NADPH + H+
: One carbon pool by folate,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism,
Biosynthesis of cofactors
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism,
Biosynthesis of cofactors
: reductive glycine pathway of autotrophic CO2 fixation,
folate transformations I,
reductive acetyl coenzyme A pathway I (homoacetogenic bacteria),
formaldehyde oxidation VII (THF pathway),
formate assimilation into 5,10-methylenetetrahydrofolate,
folate transformations III (E. coli),
folate transformations II (plants),
purine nucleobases degradation II (anaerobic)
folate transformations I,
reductive acetyl coenzyme A pathway I (homoacetogenic bacteria),
formaldehyde oxidation VII (THF pathway),
formate assimilation into 5,10-methylenetetrahydrofolate,
folate transformations III (E. coli),
folate transformations II (plants),
purine nucleobases degradation II (anaerobic)
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natural substrates
methylenetetrahydrofolate dehydrogenase (NADP+)
5,10-methylenetetrahydrofolate + NADP+ = 5,10-methenyltetrahydrofolate + NADPH + H+
: One carbon pool by folate,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism,
Biosynthesis of cofactors
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism,
Biosynthesis of cofactors
: reductive glycine pathway of autotrophic CO2 fixation,
folate transformations I,
reductive acetyl coenzyme A pathway I (homoacetogenic bacteria),
formaldehyde oxidation VII (THF pathway),
formate assimilation into 5,10-methylenetetrahydrofolate,
folate transformations III (E. coli),
folate transformations II (plants),
purine nucleobases degradation II (anaerobic)
folate transformations I,
reductive acetyl coenzyme A pathway I (homoacetogenic bacteria),
formaldehyde oxidation VII (THF pathway),
formate assimilation into 5,10-methylenetetrahydrofolate,
folate transformations III (E. coli),
folate transformations II (plants),
purine nucleobases degradation II (anaerobic)
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natural substrates
methylenetetrahydrofolate reductase [NAD(P)H]
5-methyltetrahydrofolate + oxidized ferredoxin = 5,10-methylenetetrahydrofolate + reduced ferredoxin + 2 H+
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natural substrates, generic, protein
methylenetetrahydrofolate reductase (ferredoxin)
5-methyltetrahydrofolate + oxidized ferredoxin = 5,10-methylenetetrahydrofolate + reduced ferredoxin + 2 H+
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natural substrates, generic, protein
5-methyltetrahydrofolate:corrinoid/iron-sulfur protein Co-methyltransferase
a [methyl-Co(III) corrinoid Fe-S protein] + tetrahydrofolate = a [Co(I) corrinoid Fe-S protein] + 5-methyltetrahydrofolate
: BR50170
generic compounds
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natural substrates, generic, protein
CO-methylating acetyl-CoA synthase
acetyl-CoA + a [Co(I) corrinoid Fe-S protein] = CO + CoA + a [methyl-Co(III) corrinoid Fe-S protein]
n.a.
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natural substrates, protein