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BRENDA KEGG MetaCyc

urea cycle (BRENDA)

:= BRENDA, := KEGG, := MetaCyc, := SABIO-RK
:= amino acid sequences := show the reaction diagram
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check
Missing Substrate
Missing Product
Commentary
Remark
L-ornithine N5-monooxygenase (NADPH)
L-ornithine + NADPH + H+ + O2 = N5-hydroxy-L-ornithine + NADP+ + H2O
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natural substrates
L-ornithine N5-monooxygenase [NAD(P)H]
L-ornithine + NADPH + H+ + O2 = N5-hydroxy-L-ornithine + NADP+ + H2O
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natural substrates
2-amino-4-oxopentanoate thiolase
acetyl-CoA + D-alanine = CoA + (2R)-2-amino-4-oxopentanoate
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natural substrates
2,4-diaminopentanoate dehydrogenase
(2R,4S)-2,4-diaminopentanoate + H2O + NADP+ = (2R)-2-amino-4-oxopentanoate + NH3 + NADPH + H+
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: R04200 (NAD)
natural substrates
D-ornithine 4,5-aminomutase
D-ornithine = (2R,4S)-2,4-diaminopentanoate
BR29 show the reaction diagram
R02461 show the reaction diagram
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natural substrates
urea carboxylase
ATP + urea + HCO3- + H+ = ADP + phosphate + urea-1-carboxylate
BR143 show the reaction diagram
R00774 show the reaction diagram
1126
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natural substrates
allophanate hydrolase
urea-1-carboxylate + H2O = 2 CO2 + 2 NH3
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: The yeast enzyme (but not that from green algae) also catalyses the reaction of EC 6.3.4.6 urea carboxylase, thus bringing about the hydrolysis of urea to CO2 and NH3 in the presence of ATP and bicarbonate. R00774 (6.3.4.6)
natural substrates
carbamate kinase
ATP + NH3 + hydrogencarbonate = ADP + carbamoyl phosphate + H2O
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: two-step reaction (see R01395+R12185)
natural substrates