Pathways

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BRENDA KEGG MetaCyc

glycine betaine biosynthesis (BRENDA)
:= BRENDA, := KEGG, := MetaCyc, := SABIO-RK
:= amino acid sequences := show the reaction diagram
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check
Missing Substrate
Missing Product
Commentary
Remark
glycine/sarcosine/dimethylglycine N-methyltransferase
3 S-adenosyl-L-methionine + glycine = 3 S-adenosyl-L-homocysteine + betaine
: glycine betaine biosynthesis
: BR50618show the reaction diagram
: R10062show the reaction diagram
: RXN-13406show the reaction diagram
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natural substrates
sarcosine/dimethylglycine N-methyltransferase
S-adenosyl-L-methionine + N,N-dimethylglycine = S-adenosyl-L-homocysteine + betaine + H+
: glycine betaine biosynthesis
: Glycine, serine and threonine metabolism,
Metabolic pathways
: glycine betaine biosynthesis IV (from glycine),
glycine betaine biosynthesis V (from glycine)
: BR48621show the reaction diagram
: R07244show the reaction diagram
: RXN-9680show the reaction diagram
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natural substrates
dimethylglycine N-methyltransferase
S-adenosyl-L-methionine + N,N-dimethylglycine = S-adenosyl-L-homocysteine + betaine + H+
: glycine betaine biosynthesis
: Glycine, serine and threonine metabolism,
Metabolic pathways
: glycine betaine biosynthesis IV (from glycine),
glycine betaine biosynthesis V (from glycine)
: BR48621show the reaction diagram
: R07244show the reaction diagram
: RXN-9680show the reaction diagram
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natural substrates
glycine/sarcosine/dimethylglycine N-methyltransferase
S-adenosyl-L-methionine + N,N-dimethylglycine = S-adenosyl-L-homocysteine + betaine + H+
: glycine betaine biosynthesis
: Glycine, serine and threonine metabolism,
Metabolic pathways
: glycine betaine biosynthesis IV (from glycine),
glycine betaine biosynthesis V (from glycine)
: BR48621show the reaction diagram
: R07244show the reaction diagram
: RXN-9680show the reaction diagram
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natural substrates
glycine/sarcosine N-methyltransferase
S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine
: glycine betaine biosynthesis
: glycine betaine biosynthesis IV (from glycine),
glycine betaine biosynthesis V (from glycine)
: BR48619show the reaction diagram
: R07243show the reaction diagram
: RXN-9679show the reaction diagram
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: Unlike EC 2.1.1.156 (glycine/sarcosine N-methyltransferase), EC 2.1.1.157 (sarcosine/dimethylglycine N-methyltransferase) and EC 2.1.1.161 (dimethylglycine N-methyltransferase), this enzyme, from the halophilic methanoarchaeon Methanohalophilus portucalensis, can methylate glycine and all of its intermediates to form the compatible solute betaine [17098399].
natural substrates
sarcosine/dimethylglycine N-methyltransferase
S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine
: glycine betaine biosynthesis
: glycine betaine biosynthesis IV (from glycine),
glycine betaine biosynthesis V (from glycine)
: BR48619show the reaction diagram
: R07243show the reaction diagram
: RXN-9679show the reaction diagram
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: Unlike EC 2.1.1.156 (glycine/sarcosine N-methyltransferase), EC 2.1.1.157 (sarcosine/dimethylglycine N-methyltransferase) and EC 2.1.1.161 (dimethylglycine N-methyltransferase), this enzyme, from the halophilic methanoarchaeon Methanohalophilus portucalensis, can methylate glycine and all of its intermediates to form the compatible solute betaine [17098399].
natural substrates
glycine/sarcosine/dimethylglycine N-methyltransferase
S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine
: glycine betaine biosynthesis
: glycine betaine biosynthesis IV (from glycine),
glycine betaine biosynthesis V (from glycine)
: BR48619show the reaction diagram
: R07243show the reaction diagram
: RXN-9679show the reaction diagram
-
-
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: Unlike EC 2.1.1.156 (glycine/sarcosine N-methyltransferase), EC 2.1.1.157 (sarcosine/dimethylglycine N-methyltransferase) and EC 2.1.1.161 (dimethylglycine N-methyltransferase), this enzyme, from the halophilic methanoarchaeon Methanohalophilus portucalensis, can methylate glycine and all of its intermediates to form the compatible solute betaine [17098399].
natural substrates
S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine
: glycine betaine biosynthesis
: glycine betaine biosynthesis IV (from glycine),
glycine betaine biosynthesis V (from glycine)
: BR48619show the reaction diagram
: R07243show the reaction diagram
: RXN-9679show the reaction diagram
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-
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: Unlike EC 2.1.1.156 (glycine/sarcosine N-methyltransferase), EC 2.1.1.157 (sarcosine/dimethylglycine N-methyltransferase) and EC 2.1.1.161 (dimethylglycine N-methyltransferase), this enzyme, from the halophilic methanoarchaeon Methanohalophilus portucalensis, can methylate glycine and all of its intermediates to form the compatible solute betaine [17098399].
natural substrates
glycine/sarcosine N-methyltransferase
S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine + sarcosine
: glycine betaine biosynthesis
: Glycine, serine and threonine metabolism,
Metabolic pathways
: glycine betaine biosynthesis V (from glycine),
glycine betaine biosynthesis IV (from glycine)
: BR43887show the reaction diagram
: R00367show the reaction diagram
: GLYCINE-N-METHYLTRANSFERASE-RXNshow the reaction diagram
: 834
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: further methylation of sarcosine to N,N-dimethylglycine (ec 2.1.1.156, see R07243)
natural substrates
glycine/sarcosine/dimethylglycine N-methyltransferase
S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine + sarcosine
: glycine betaine biosynthesis
: Glycine, serine and threonine metabolism,
Metabolic pathways
: glycine betaine biosynthesis V (from glycine),
glycine betaine biosynthesis IV (from glycine)
: BR43887show the reaction diagram
: R00367show the reaction diagram
: GLYCINE-N-METHYLTRANSFERASE-RXNshow the reaction diagram
: 834
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: further methylation of sarcosine to N,N-dimethylglycine (ec 2.1.1.156, see R07243)
natural substrates
glycine N-methyltransferase
S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine + sarcosine
: glycine betaine biosynthesis
: Glycine, serine and threonine metabolism,
Metabolic pathways
: glycine betaine biosynthesis V (from glycine),
glycine betaine biosynthesis IV (from glycine)
: BR43887show the reaction diagram
: R00367show the reaction diagram
: GLYCINE-N-METHYLTRANSFERASE-RXNshow the reaction diagram
: 834
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: further methylation of sarcosine to N,N-dimethylglycine (ec 2.1.1.156, see R07243)
natural substrates
phospholipase D
a phosphatidylcholine + H2O = choline + a phosphatidate
: glycine betaine biosynthesis
: Glycerophospholipid metabolism,
Metabolic pathways,
Biosynthesis of secondary metabolites
: phospholipases,
phosphatidate metabolism, as a signaling molecule,
choline biosynthesis III
: BR15961show the reaction diagram
: R01310show the reaction diagram
: PHOSCHOL-RXNshow the reaction diagram
: 1525
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natural substrates
sphingomyelin phosphodiesterase D
a phosphatidylcholine + H2O = choline + a phosphatidate
: glycine betaine biosynthesis
: Glycerophospholipid metabolism,
Metabolic pathways,
Biosynthesis of secondary metabolites
: phospholipases,
phosphatidate metabolism, as a signaling molecule,
choline biosynthesis III
: BR15961show the reaction diagram
: R01310show the reaction diagram
: PHOSCHOL-RXNshow the reaction diagram
: 1525
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natural substrates
aminobutyraldehyde dehydrogenase
betaine aldehyde + NAD+ + H2O = betaine + NADH + 2 H+
: glycine betaine biosynthesis
: Glycine, serine and threonine metabolism,
Metabolic pathways
: choline degradation IV,
glycine betaine biosynthesis III (plants),
choline degradation I,
glycine betaine biosynthesis II (Gram-positive bacteria),
glycine betaine biosynthesis I (Gram-negative bacteria)
: BR36784show the reaction diagram
: R02565show the reaction diagram
: BADH-RXNshow the reaction diagram
: 2478
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natural substrates
glycolaldehyde dehydrogenase
betaine aldehyde + NAD+ + H2O = betaine + NADH + 2 H+
: glycine betaine biosynthesis
: Glycine, serine and threonine metabolism,
Metabolic pathways
: choline degradation IV,
glycine betaine biosynthesis III (plants),
choline degradation I,
glycine betaine biosynthesis II (Gram-positive bacteria),
glycine betaine biosynthesis I (Gram-negative bacteria)
: BR36784show the reaction diagram
: R02565show the reaction diagram
: BADH-RXNshow the reaction diagram
: 2478
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natural substrates
succinate-semialdehyde dehydrogenase (NAD+)
betaine aldehyde + NAD+ + H2O = betaine + NADH + 2 H+
: glycine betaine biosynthesis
: Glycine, serine and threonine metabolism,
Metabolic pathways
: choline degradation IV,
glycine betaine biosynthesis III (plants),
choline degradation I,
glycine betaine biosynthesis II (Gram-positive bacteria),
glycine betaine biosynthesis I (Gram-negative bacteria)
: BR36784show the reaction diagram
: R02565show the reaction diagram
: BADH-RXNshow the reaction diagram
: 2478
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natural substrates
aldehyde dehydrogenase (NAD+)
betaine aldehyde + NAD+ + H2O = betaine + NADH + 2 H+
: glycine betaine biosynthesis
: Glycine, serine and threonine metabolism,
Metabolic pathways
: choline degradation IV,
glycine betaine biosynthesis III (plants),
choline degradation I,
glycine betaine biosynthesis II (Gram-positive bacteria),
glycine betaine biosynthesis I (Gram-negative bacteria)
: BR36784show the reaction diagram
: R02565show the reaction diagram
: BADH-RXNshow the reaction diagram
: 2478
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natural substrates
4-trimethylammoniobutyraldehyde dehydrogenase
betaine aldehyde + NAD+ + H2O = betaine + NADH + 2 H+
: glycine betaine biosynthesis
: Glycine, serine and threonine metabolism,
Metabolic pathways
: choline degradation IV,
glycine betaine biosynthesis III (plants),
choline degradation I,
glycine betaine biosynthesis II (Gram-positive bacteria),
glycine betaine biosynthesis I (Gram-negative bacteria)
: BR36784show the reaction diagram
: R02565show the reaction diagram
: BADH-RXNshow the reaction diagram
: 2478
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natural substrates
betaine-aldehyde dehydrogenase
betaine aldehyde + NAD+ + H2O = betaine + NADH + 2 H+
: glycine betaine biosynthesis
: Glycine, serine and threonine metabolism,
Metabolic pathways
: choline degradation IV,
glycine betaine biosynthesis III (plants),
choline degradation I,
glycine betaine biosynthesis II (Gram-positive bacteria),
glycine betaine biosynthesis I (Gram-negative bacteria)
: BR36784show the reaction diagram
: R02565show the reaction diagram
: BADH-RXNshow the reaction diagram
: 2478
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natural substrates
choline dehydrogenase
choline + acceptor = betaine aldehyde + reduced acceptor
: glycine betaine biosynthesis
: Glycine, serine and threonine metabolism,
Metabolic pathways
: choline degradation I,
glycine betaine biosynthesis I (Gram-negative bacteria)
: BR36747show the reaction diagram
: R01025show the reaction diagram
: CHD-RXNshow the reaction diagram
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natural substrates, generic